Pablo F. Céspedes
@pfcespedes.bsky.social
Group Leader at the University of Oxford. My goal is to identify human-specific mechanisms regulating lymphocyte function. Developing advanced ex vivo models to study the beautiful and unique intersection of metabolism, PTMs and immune cell signalling.
A fascinating advance in extracellular biology — Claire’s new pre-print unveils Thrombospondin Encapsulated Dense Particles (ThrEDs), a new class of non-vesicular extracellular particles with potent wound-healing & anti-fibrotic activity.
📄 www.biorxiv.org/content/10.1...
#ExtracellularParticles
📄 www.biorxiv.org/content/10.1...
#ExtracellularParticles
Thrombospondin Encapsulated Dense Particles accelerate wound healing and downregulate fibrotic phenotypes
Extracellular particles (EP) released by cells are heterogenous, with extracellular vesicles (EV) believed to be the major component. To investigate different EV subpopulations, we conducted a panel s...
www.biorxiv.org
October 13, 2025 at 4:28 PM
A fascinating advance in extracellular biology — Claire’s new pre-print unveils Thrombospondin Encapsulated Dense Particles (ThrEDs), a new class of non-vesicular extracellular particles with potent wound-healing & anti-fibrotic activity.
📄 www.biorxiv.org/content/10.1...
#ExtracellularParticles
📄 www.biorxiv.org/content/10.1...
#ExtracellularParticles
Reposted by Pablo F. Céspedes
ASM, ASBMB, ASCB & FASEB are deeply disappointed in the Supreme Court ruling allowing cancellation of $800M in NIH grants, threatening labs, jobs, and early-career scientists. Stable funding is vital for U.S. science.
Read more: www.ascb.org/society-news...
Read more: www.ascb.org/society-news...
Statement on Supreme Court Ruling in American Public Health Association v. NIH - ASCB
The American Society for Microbiology (ASM), the American Society for Biochemistry and Molecular Biology (ASBMB), the American Society for Cell Biology (ASCB) and the Federation of American Societies ...
www.ascb.org
August 22, 2025 at 7:44 PM
ASM, ASBMB, ASCB & FASEB are deeply disappointed in the Supreme Court ruling allowing cancellation of $800M in NIH grants, threatening labs, jobs, and early-career scientists. Stable funding is vital for U.S. science.
Read more: www.ascb.org/society-news...
Read more: www.ascb.org/society-news...
Reposted by Pablo F. Céspedes
🧪 The personal testimony of a scientist at Harvard Med School now incarcerated by ICE in Louisiana:
“I haven’t been in my lab or worked with my microscope since February, when I was detained by ICE as I was returning to Boston from a vacation in France”
Gift link:
www.nytimes.com/2025/05/13/o...
“I haven’t been in my lab or worked with my microscope since February, when I was detained by ICE as I was returning to Boston from a vacation in France”
Gift link:
www.nytimes.com/2025/05/13/o...
Opinion | The Science I Would Be Doing if I Weren’t in ICE Detention
www.nytimes.com
May 13, 2025 at 11:10 AM
🧪 The personal testimony of a scientist at Harvard Med School now incarcerated by ICE in Louisiana:
“I haven’t been in my lab or worked with my microscope since February, when I was detained by ICE as I was returning to Boston from a vacation in France”
Gift link:
www.nytimes.com/2025/05/13/o...
“I haven’t been in my lab or worked with my microscope since February, when I was detained by ICE as I was returning to Boston from a vacation in France”
Gift link:
www.nytimes.com/2025/05/13/o...
Reposted by Pablo F. Céspedes
Researchers at Rice University have developed a new machine learning model that makes optical spectroscopy data easier and quicker to interpret >>> www.biotechniques.com/computationa... 🧪
Now you see me: machine learning model makes spectra clearer
Researchers have developed a machine learning model that helps interpret optical spectroscopy data.
www.biotechniques.com
May 8, 2025 at 11:35 AM
Researchers at Rice University have developed a new machine learning model that makes optical spectroscopy data easier and quicker to interpret >>> www.biotechniques.com/computationa... 🧪
Reposted by Pablo F. Céspedes
24 h of crowd power ➡️ live table of every placebo-controlled vaccine RCT
- 27 trials logged so far (>2 M participants)
- Control-type tag = saline vs active comparator
Contribute / explore 👇
bit.ly/3EuYzqI
cc @statnews.com @kffhealthnews.org
- 27 trials logged so far (>2 M participants)
- Control-type tag = saline vs active comparator
Contribute / explore 👇
bit.ly/3EuYzqI
cc @statnews.com @kffhealthnews.org
April 23, 2025 at 10:33 PM
24 h of crowd power ➡️ live table of every placebo-controlled vaccine RCT
- 27 trials logged so far (>2 M participants)
- Control-type tag = saline vs active comparator
Contribute / explore 👇
bit.ly/3EuYzqI
cc @statnews.com @kffhealthnews.org
- 27 trials logged so far (>2 M participants)
- Control-type tag = saline vs active comparator
Contribute / explore 👇
bit.ly/3EuYzqI
cc @statnews.com @kffhealthnews.org
Reposted by Pablo F. Céspedes
105 controlled vaccine trials.
110 yrs. 1.8 M participants.
All in one live, crowd-sourced sheet.
Built by contributors worldwide to counter the myth that vaccines weren’t tested with controls.
Quiet work still breaks through the noise.
www.bradspellberg.com/vaccine-rcts
@bradspellberg.bsky.social
110 yrs. 1.8 M participants.
All in one live, crowd-sourced sheet.
Built by contributors worldwide to counter the myth that vaccines weren’t tested with controls.
Quiet work still breaks through the noise.
www.bradspellberg.com/vaccine-rcts
@bradspellberg.bsky.social
May 6, 2025 at 3:02 PM
105 controlled vaccine trials.
110 yrs. 1.8 M participants.
All in one live, crowd-sourced sheet.
Built by contributors worldwide to counter the myth that vaccines weren’t tested with controls.
Quiet work still breaks through the noise.
www.bradspellberg.com/vaccine-rcts
@bradspellberg.bsky.social
110 yrs. 1.8 M participants.
All in one live, crowd-sourced sheet.
Built by contributors worldwide to counter the myth that vaccines weren’t tested with controls.
Quiet work still breaks through the noise.
www.bradspellberg.com/vaccine-rcts
@bradspellberg.bsky.social
Reposted by Pablo F. Céspedes
The plots of disaster movies that portray the end of civilization often begin with high-level Government Officials ignoring the warnings of Scientists.
One of several lesson learned from the 2.5 hour @Netflix Documentary — Don’t Look Up (2021).
One of several lesson learned from the 2.5 hour @Netflix Documentary — Don’t Look Up (2021).
May 4, 2025 at 1:15 PM
The plots of disaster movies that portray the end of civilization often begin with high-level Government Officials ignoring the warnings of Scientists.
One of several lesson learned from the 2.5 hour @Netflix Documentary — Don’t Look Up (2021).
One of several lesson learned from the 2.5 hour @Netflix Documentary — Don’t Look Up (2021).
Reposted by Pablo F. Céspedes
Trumpty-Dumpty is defunding PBS. What he calls "bias" some of us call "facts Trumpty-Dumpty doesn't like."
May 2, 2025 at 1:56 PM
Trumpty-Dumpty is defunding PBS. What he calls "bias" some of us call "facts Trumpty-Dumpty doesn't like."
Reposted by Pablo F. Céspedes
Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".
May 2, 2025 at 2:27 AM
Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".