BioTechniques
@biotechniques.bsky.social
BioTechniques, part of Taylor and Francis, is an open access journal and website, providing the latest news and research in life science methods | Est. 1983
Fine-tuning a gene centrally involved in regulating the immune system offers potential clues for future autoimmunity and cancer treatments >>> www.biotechniques.com/crispr/regul... 🧪
Regulating the gene essential to immune system balance
Researchers have mapped the regulatory elements that control the FOXP3 gene, which is implicated in maintaining balance in the immune system.
www.biotechniques.com
November 17, 2025 at 4:16 PM
Fine-tuning a gene centrally involved in regulating the immune system offers potential clues for future autoimmunity and cancer treatments >>> www.biotechniques.com/crispr/regul... 🧪
For the first time, researchers have captured the chameleon’s coiled optic nerve using contrast enhanced computed tomography >>> www.biotechniques.com/imaging/the-... 🧪
The coiled history of the chameleon optic nerve
Researchers have shown that the chameleon has a coiled optic nerve, which they believe allows the lizard to increase their field of vision.
www.biotechniques.com
November 14, 2025 at 11:28 AM
For the first time, researchers have captured the chameleon’s coiled optic nerve using contrast enhanced computed tomography >>> www.biotechniques.com/imaging/the-... 🧪
Researchers have discovered a vulnerability in the bacteria that cause Lyme disease >>> www.biotechniques.com/molecular-bi... 🧪
Manganese: a double-edged sword in Lyme disease
Researchers uncovered that disrupting manganese in the bacteria that cause Lyme disease could be key to weakening the pathogen.
www.biotechniques.com
November 13, 2025 at 3:18 PM
Researchers have discovered a vulnerability in the bacteria that cause Lyme disease >>> www.biotechniques.com/molecular-bi... 🧪
In the STEM Tea podcast, @phdgprotein86.bsky.social sits down with Lindsey Keith-Vincent, Associate Dean at Louisiana Tech University, to explore her unique model for supporting faculty, mentoring students and fostering a culture of authenticity >>> www.biotechniques.com/podcasts/ste... 🧪
STEM Tea | Humans first, professionals second
In this episode, AJ Hinton is joined by Lindsey Keith-Vincent, a first-generation college graduate who is passionate about STEM education.
www.biotechniques.com
November 13, 2025 at 12:07 PM
In the STEM Tea podcast, @phdgprotein86.bsky.social sits down with Lindsey Keith-Vincent, Associate Dean at Louisiana Tech University, to explore her unique model for supporting faculty, mentoring students and fostering a culture of authenticity >>> www.biotechniques.com/podcasts/ste... 🧪
The latest biotech industry insights >>> www.biotechniques.com/molecular-bi... 🧪
The biotech bi-weekly: protein quantification, AMR mutation characterization and automating single-cell transcriptomics
In this edition of the biotech bi-weekly, read about recent product launches that are quantifying His-tagged proteins and characterizing AMR mutations.
www.biotechniques.com
November 12, 2025 at 10:00 AM
The latest biotech industry insights >>> www.biotechniques.com/molecular-bi... 🧪
At @elrig.org’s Drug Discovery 2025, we spoke to Heather Pinkett – President of The Protein Society – to learn more about ABC transporters and what targeting them could mean for combatting antimicrobial resistance >>> www.biotechniques.com/microbiology... 🧪
Targeting ABC to tackle AMR: taking advantage of bacterial membrane proteins
Heather Pinkett tells us about her research investigating ABC transporters in pathogenic bacteria and what this could mean for tackling AMR.
www.biotechniques.com
November 11, 2025 at 3:01 PM
At @elrig.org’s Drug Discovery 2025, we spoke to Heather Pinkett – President of The Protein Society – to learn more about ABC transporters and what targeting them could mean for combatting antimicrobial resistance >>> www.biotechniques.com/microbiology... 🧪
Researchers have discovered that the enzyme NUDT5 helps to switch off purine production – the chemical pathway that generates the building blocks of DNA – but does so without using its enzymatic activity >>> www.biotechniques.com/molecular-bi... 🧪
Enzyme scaffold restricts key pathway in DNA synthesis
Researchers have discovered that the enzyme NUDT5 utilizes its structure to exercise metabolic control over a key pathway in DNA synthesis.
www.biotechniques.com
November 11, 2025 at 12:02 PM
Researchers have discovered that the enzyme NUDT5 helps to switch off purine production – the chemical pathway that generates the building blocks of DNA – but does so without using its enzymatic activity >>> www.biotechniques.com/molecular-bi... 🧪
Researchers from Texas Tech University have developed a method that could allow scientists to bypass one of the most time-consuming and technically challenging steps in plant biotechnology – tissue culture >>> www.biotechniques.com/plant-climat... 🧪
A synthetic regeneration cascade for genetically editing crops
Researchers have developed a synthetic regeneration system for genetically editing crops, avoiding the challenging step of tissue culturing.
www.biotechniques.com
November 10, 2025 at 3:56 PM
Researchers from Texas Tech University have developed a method that could allow scientists to bypass one of the most time-consuming and technically challenging steps in plant biotechnology – tissue culture >>> www.biotechniques.com/plant-climat... 🧪
Two separate studies have identified age-related molecular changes in the rat brain and adjusted them to improve memory >>> www.biotechniques.com/neuroscience... 🧪
CRISPR for improving memory in aging brains
Researchers have used CRISPR gene editing to adjust age-related molecular mechanisms to target memory loss.
www.biotechniques.com
November 6, 2025 at 4:04 PM
Two separate studies have identified age-related molecular changes in the rat brain and adjusted them to improve memory >>> www.biotechniques.com/neuroscience... 🧪
How paradigm-shifting could an AI-first drug discovery company be?
At @elrig.org’s Drug Discovery 2025, we spoke to Miles Congreve, Chief Scientific Officer at @isomorphiclabs.bsky.social, to find out >>> www.biotechniques.com/drug-discove... 🧪
At @elrig.org’s Drug Discovery 2025, we spoke to Miles Congreve, Chief Scientific Officer at @isomorphiclabs.bsky.social, to find out >>> www.biotechniques.com/drug-discove... 🧪
How will AI-first drug design transform human health?
Find out how developments in AlphaFold 3, alongside new predictive models, are changing approaches to drug discovery and design.
www.biotechniques.com
November 6, 2025 at 2:22 PM
How paradigm-shifting could an AI-first drug discovery company be?
At @elrig.org’s Drug Discovery 2025, we spoke to Miles Congreve, Chief Scientific Officer at @isomorphiclabs.bsky.social, to find out >>> www.biotechniques.com/drug-discove... 🧪
At @elrig.org’s Drug Discovery 2025, we spoke to Miles Congreve, Chief Scientific Officer at @isomorphiclabs.bsky.social, to find out >>> www.biotechniques.com/drug-discove... 🧪
By stimulating cancer cells to produce a molecule that activates a signaling pathway in nearby immune cells, researchers have found a way to force tumors to trigger their own destruction >>> www.biotechniques.com/cancer-resea... 🧪
A cancer cell’s mRNA guide to self-sabotage
Researchers have harnessed the cGAS-STING pathway using mRNA to slow tumor growth in mouse models of cancer.
www.biotechniques.com
November 5, 2025 at 12:06 PM
By stimulating cancer cells to produce a molecule that activates a signaling pathway in nearby immune cells, researchers have found a way to force tumors to trigger their own destruction >>> www.biotechniques.com/cancer-resea... 🧪
A new study provides unprecedented insights into the cellular architecture of over 200 species of plankton using ultrastructure expansion microscopy >>> www.biotechniques.com/imaging/expa... 🧪
Expanding our insights into the planktonic universe
Researchers have utilized ultrastructure expansion microscopy to reveal more about the cytoskeletal characteristics of the planktonic universe.
www.biotechniques.com
November 4, 2025 at 4:07 PM
A new study provides unprecedented insights into the cellular architecture of over 200 species of plankton using ultrastructure expansion microscopy >>> www.biotechniques.com/imaging/expa... 🧪
Cryo-electron tomography has captured how synaptic vesicles transmit information across synapses > > > www.biotechniques.com/neuroscience... 🧪
Neurons ‘kiss-shrink-run’ to relay information
Cryo-ET reveals the 'kiss-shrink-run' fusion model to explain how neurons transmit signals across synapses.
www.biotechniques.com
November 3, 2025 at 3:58 PM
Cryo-electron tomography has captured how synaptic vesicles transmit information across synapses > > > www.biotechniques.com/neuroscience... 🧪
🧟 Researchers have developed a way to tag senescent ‘zombie’ cells that allows for both identification and characterization of these cells, which are often implicated in disease >>> www.biotechniques.com/cell-and-tis... 🧪
Hunting zombie cells: novel technique for tagging senescent cells
Researchers have developed a new technique for tagging senescent cells with DNA aptamers to identify and characterize these cells.
www.biotechniques.com
October 31, 2025 at 11:01 AM
🧟 Researchers have developed a way to tag senescent ‘zombie’ cells that allows for both identification and characterization of these cells, which are often implicated in disease >>> www.biotechniques.com/cell-and-tis... 🧪
An AI tool identifies cells that can shed light on the earliest origins of cancer through a game of molecular ‘laser tag’ >>> www.biotechniques.com/computationa... 🧪
Molecular laser tag: identifying chromosomal abnormalities with AI
Researchers have developed an AI-assisted technology that can identify and tag chromosomal abnormalities in cells.
www.biotechniques.com
October 29, 2025 at 4:07 PM
An AI tool identifies cells that can shed light on the earliest origins of cancer through a game of molecular ‘laser tag’ >>> www.biotechniques.com/computationa... 🧪
An electromagnetic device can gently sort cells by levitating them to different heights >>> www.biotechniques.com/cell-and-tis... 🧪
Just like magic: the technique behind cellular levitation
Researchers have developed a novel electromagnetic cell sorting technique for separating different cell types.
www.biotechniques.com
October 29, 2025 at 2:49 PM
An electromagnetic device can gently sort cells by levitating them to different heights >>> www.biotechniques.com/cell-and-tis... 🧪
🔬 Meet the researcher behind the image that won the BioTechniques Image Competition 2025 📸
In this interview, we learn more about Bruno Cisterna, his winning image, his favorite microscopy techniques and his advice for burgeoning microscopists >>> www.biotechniques.com/imaging/meet... 🧪
In this interview, we learn more about Bruno Cisterna, his winning image, his favorite microscopy techniques and his advice for burgeoning microscopists >>> www.biotechniques.com/imaging/meet... 🧪
Meet the researcher behind the 2025 winning image
Read the interview with this year's Image Competition winner to learn more about how he captured this scientific image.
www.biotechniques.com
October 28, 2025 at 3:28 PM
🔬 Meet the researcher behind the image that won the BioTechniques Image Competition 2025 📸
In this interview, we learn more about Bruno Cisterna, his winning image, his favorite microscopy techniques and his advice for burgeoning microscopists >>> www.biotechniques.com/imaging/meet... 🧪
In this interview, we learn more about Bruno Cisterna, his winning image, his favorite microscopy techniques and his advice for burgeoning microscopists >>> www.biotechniques.com/imaging/meet... 🧪
A brain circuit involving leptin allows mice to carry out vital behaviors, such as eating and sleeping, during anxious episodes >>> www.biotechniques.com/neuroscience... 🧪
Leptin neural circuit restores balance after anxiety upsets it
Research has shown that a brain circuit involving leptin helps mice execute vital behaviors even when anxious.
www.biotechniques.com
October 27, 2025 at 5:13 PM
A brain circuit involving leptin allows mice to carry out vital behaviors, such as eating and sleeping, during anxious episodes >>> www.biotechniques.com/neuroscience... 🧪
This article explains the importance of cellular annotation in spatial analysis, highlighting the techniques and tricks the authors use in their own approach to cellular annotation >>> www.biotechniques.com/cell-and-tis... 🧪
October 24, 2025 at 10:48 AM
This article explains the importance of cellular annotation in spatial analysis, highlighting the techniques and tricks the authors use in their own approach to cellular annotation >>> www.biotechniques.com/cell-and-tis... 🧪
A new large language model predicts the properties of lasso peptides, natural products of bacteria that have therapeutic potential >>> www.biotechniques.com/computationa...
Lassoing new therapeutics with computational biology
A new large language model predicts the properties of lasso peptides, natural products of bacteria that have therapeutic potential.
www.biotechniques.com
October 24, 2025 at 10:44 AM
A new large language model predicts the properties of lasso peptides, natural products of bacteria that have therapeutic potential >>> www.biotechniques.com/computationa...
How are we improving the way the field of drug discovery creates machine learning algorithms to predict a protein’s interactions with a small molecule? >>> www.biotechniques.com/computationa... 🧪
A targeted approach to using AI in drug discovery
A researcher has proposed a more targeted approach to AI drug discovery, which includes a rigorous evaluation protocol.
www.biotechniques.com
October 23, 2025 at 8:49 AM
How are we improving the way the field of drug discovery creates machine learning algorithms to predict a protein’s interactions with a small molecule? >>> www.biotechniques.com/computationa... 🧪
In this STEM Tea podcast episode, @phdgprotein86.bsky.social and his guests discuss the importance of STEM education in K-12 schools and how these programs can support and expand students’ career prospects, sense of belonging and scientific exploration >>> www.biotechniques.com/podcasts/ste... 🧪
www.biotechniques.com
October 21, 2025 at 5:17 PM
In this STEM Tea podcast episode, @phdgprotein86.bsky.social and his guests discuss the importance of STEM education in K-12 schools and how these programs can support and expand students’ career prospects, sense of belonging and scientific exploration >>> www.biotechniques.com/podcasts/ste... 🧪
Researchers have combined DNA and inorganic materials to build a microscopic robot that can act dynamically in response to its environment >>> www.biotechniques.com/drug-discove... 🧪
Flower power: the development of dynamic microscopic robots
Researchers have combined DNA and inorganic materials to build a DNA-based robot that can act dynamically in response to its environment.
www.biotechniques.com
October 21, 2025 at 12:49 PM
Researchers have combined DNA and inorganic materials to build a microscopic robot that can act dynamically in response to its environment >>> www.biotechniques.com/drug-discove... 🧪
Researchers have found two enzymes that encourage prostate cancer growth and treatment resistance > > > www.biotechniques.com/cancer-resea... 🧪
Targeting prostate cancer’s Achilles’ heel
Scientists have identified two enzymes that help prostate cancer cells grow, survive and resist treatment, paving the way for new treatments.
www.biotechniques.com
October 20, 2025 at 1:34 PM
Researchers have found two enzymes that encourage prostate cancer growth and treatment resistance > > > www.biotechniques.com/cancer-resea... 🧪
🦠💊 Are mixtures of commonly used medications that end up in our waterways and natural environments increasing the development of antibiotic-resistant bacteria? >>> www.biotechniques.com/microbiology... 🧪
Non-antibiotic medications in the environment could exacerbate AMR
Researchers have revealed how non-antibiotic medications in natural environments could be contributing to antimicrobial resistance.
www.biotechniques.com
October 16, 2025 at 9:48 AM
🦠💊 Are mixtures of commonly used medications that end up in our waterways and natural environments increasing the development of antibiotic-resistant bacteria? >>> www.biotechniques.com/microbiology... 🧪