Univ. of Pennsylvania Department of Cancer Biology
@penncbio.bsky.social
Official Twitter of the Department of Cancer Biology at The University of Pennsylvania Perelman School of Medicine (@pennmedicine.bsky.social). Tweets are our own.
Reposted by Univ. of Pennsylvania Department of Cancer Biology
Systematic evaluation of GAPs and GEFs identifies a targetable dependency for hematopoietic malignancies ft. Yuqiao Liu & Junwei Shi (@penncbio.bsky.social) @aacrjournals.bsky.social aacrjournals.org/cancerdiscov...
September 25, 2025 at 4:42 PM
Systematic evaluation of GAPs and GEFs identifies a targetable dependency for hematopoietic malignancies ft. Yuqiao Liu & Junwei Shi (@penncbio.bsky.social) @aacrjournals.bsky.social aacrjournals.org/cancerdiscov...
Reposted by Univ. of Pennsylvania Department of Cancer Biology
📣 New preprint 📣
We present a detailed map of nascent and mature ribosomal RNAs in mouse hematopoiesis and AML (including absolute rRNA molecule numbers), and outline principles of rDNA regulation.
Work by Eleanor Sams (@eleanor44.bsky.social) & Victoria Feist (@victoriafeist.bsky.social). (1/x)
We present a detailed map of nascent and mature ribosomal RNAs in mouse hematopoiesis and AML (including absolute rRNA molecule numbers), and outline principles of rDNA regulation.
Work by Eleanor Sams (@eleanor44.bsky.social) & Victoria Feist (@victoriafeist.bsky.social). (1/x)
Dynamics of Ribosomal RNA Transcription and Abundance in Normal and Leukemic Hematopoiesis
Transcription of ribosomal RNAs (rRNAs) from rDNA repeats is the first step of ribosome biogenesis, accounting for a major portion of all cellular transcription. Often regarded as a housekeeping proce...
www.biorxiv.org
August 2, 2025 at 5:50 PM
📣 New preprint 📣
We present a detailed map of nascent and mature ribosomal RNAs in mouse hematopoiesis and AML (including absolute rRNA molecule numbers), and outline principles of rDNA regulation.
Work by Eleanor Sams (@eleanor44.bsky.social) & Victoria Feist (@victoriafeist.bsky.social). (1/x)
We present a detailed map of nascent and mature ribosomal RNAs in mouse hematopoiesis and AML (including absolute rRNA molecule numbers), and outline principles of rDNA regulation.
Work by Eleanor Sams (@eleanor44.bsky.social) & Victoria Feist (@victoriafeist.bsky.social). (1/x)
Reposted by Univ. of Pennsylvania Department of Cancer Biology
Amy Gladstein in the Feldser lab defends her thesis tomorrow!
August 27, 2025 at 5:03 PM
Amy Gladstein in the Feldser lab defends her thesis tomorrow!
Reposted by Univ. of Pennsylvania Department of Cancer Biology
Congratulations to @LilingWanLab (@penncbio.bsky.social/ @penncancer.bsky.social), recipient of a 2025 @PershingSqFdn Sohn Cancer Prize! tinyurl.com/zse5mbj4
July 15, 2025 at 6:31 PM
Congratulations to @LilingWanLab (@penncbio.bsky.social/ @penncancer.bsky.social), recipient of a 2025 @PershingSqFdn Sohn Cancer Prize! tinyurl.com/zse5mbj4
Reposted by Univ. of Pennsylvania Department of Cancer Biology
ft. Siera Tomishima, Dale Kim, @YohanizOrtega, Paula Oliver (@pennpathlabmed.bsky.social), Robert Bowman (@penncbio.bsky.social), Nadia Porter, Ipsita Guha, @dar_darasif, Jennifer Roof, Hossein Fazelinia, Lynn Spruce & Christopher Thom (@chopresearch.bsky.social) www.jci.org/articles/vie...
July 15, 2025 at 6:34 PM
ft. Siera Tomishima, Dale Kim, @YohanizOrtega, Paula Oliver (@pennpathlabmed.bsky.social), Robert Bowman (@penncbio.bsky.social), Nadia Porter, Ipsita Guha, @dar_darasif, Jennifer Roof, Hossein Fazelinia, Lynn Spruce & Christopher Thom (@chopresearch.bsky.social) www.jci.org/articles/vie...
Reposted by Univ. of Pennsylvania Department of Cancer Biology
#TuesdayMotivation | Meet Donita Brady (@bradylabupenn.bsky.social) at @pennmedicine.bsky.social (@penncbio.bsky.social & @rtaatpennmed.bsky.social): ow.ly/2hbi50WIzuM.
Her lab investigates how copper modulates signal transduction in healthy and cancerous cells.
#CancerResearch #tumorigenesis
Her lab investigates how copper modulates signal transduction in healthy and cancerous cells.
#CancerResearch #tumorigenesis
Meet Donita Brady
Donita Brady is an associate professor of cancer biology and an associate editor of the Journal of Biological Chemistry, who studies metalloallostery in cancer.
ow.ly
August 20, 2025 at 3:09 AM
#TuesdayMotivation | Meet Donita Brady (@bradylabupenn.bsky.social) at @pennmedicine.bsky.social (@penncbio.bsky.social & @rtaatpennmed.bsky.social): ow.ly/2hbi50WIzuM.
Her lab investigates how copper modulates signal transduction in healthy and cancerous cells.
#CancerResearch #tumorigenesis
Her lab investigates how copper modulates signal transduction in healthy and cancerous cells.
#CancerResearch #tumorigenesis
Reposted by Univ. of Pennsylvania Department of Cancer Biology
Congratulations to @bradylabupenn.bsky.social (@penncbio.bsky.social/ @rtaatpennmed.bsky.social), recipient of the 2026 @asbmb.bsky.social Ruth Kirschstein Award for Maximizing Access in Science! tinyurl.com/6w7n3uzx
September 16, 2025 at 9:01 PM
Congratulations to @bradylabupenn.bsky.social (@penncbio.bsky.social/ @rtaatpennmed.bsky.social), recipient of the 2026 @asbmb.bsky.social Ruth Kirschstein Award for Maximizing Access in Science! tinyurl.com/6w7n3uzx
Reposted by Univ. of Pennsylvania Department of Cancer Biology
A 1st-of-its-kind clinical trial identified risk of breast cancer recurrence & successfully treated dormant tumor cells using existing drugs ft. @angiedemichele.bsky.social (@penncancer.bsky.social) & Lewis Chodosh (@penncbio.bsky.social) tinyurl.com/mryru5ew
September 17, 2025 at 3:20 PM
A 1st-of-its-kind clinical trial identified risk of breast cancer recurrence & successfully treated dormant tumor cells using existing drugs ft. @angiedemichele.bsky.social (@penncancer.bsky.social) & Lewis Chodosh (@penncbio.bsky.social) tinyurl.com/mryru5ew
Reposted by Univ. of Pennsylvania Department of Cancer Biology
Congratulations to @rdrapkin8-penn.bsky.social (@PennOBGYN), recipient of a 2025 @PershingSqFdn Ovarian Cancer Challenge Grant! @Penn_OCRC @penncancer.bsky.social @BasserBRCA tinyurl.com/yjvvyr4k
June 18, 2025 at 1:44 PM
Congratulations to @rdrapkin8-penn.bsky.social (@PennOBGYN), recipient of a 2025 @PershingSqFdn Ovarian Cancer Challenge Grant! @Penn_OCRC @penncancer.bsky.social @BasserBRCA tinyurl.com/yjvvyr4k
Reposted by Univ. of Pennsylvania Department of Cancer Biology
New preprint for Amy Gladstein (@amygladstein) in the @Feldserlab on: The H3 K36M oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer pubmed.ncbi.nlm.nih.gov/40501771/
The H3 K36M oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer - PubMed
Mutations in histone 3 at or near lysine 36 (H3K36) have dominantly acting oncogenic effects in multiple tumor types by limiting H3K36-directed methyltransferases. Paradoxically, we find that…
pubmed.ncbi.nlm.nih.gov
June 18, 2025 at 4:06 PM
New preprint for Amy Gladstein (@amygladstein) in the @Feldserlab on: The H3 K36M oncohistone inhibits NSD2 to activate a SETD2-dependent antiviral-like immune response in KRAS-driven lung cancer pubmed.ncbi.nlm.nih.gov/40501771/
Reposted by Univ. of Pennsylvania Department of Cancer Biology
Join @BB_UPenn, @penncbio.bsky.social, @PennCDB, @CAMBUpenn, @UPennEEJust, @duboiscircle, @RTAatPennMed on Wednesday, 6/18 at 1pm for the 3rd annual #Juneteenth seminar ft'ing keynote speaker Dr. Squire Booker. Learn more➡️ tinyurl.com/kpnetx9f
June 16, 2025 at 5:23 PM
Join @BB_UPenn, @penncbio.bsky.social, @PennCDB, @CAMBUpenn, @UPennEEJust, @duboiscircle, @RTAatPennMed on Wednesday, 6/18 at 1pm for the 3rd annual #Juneteenth seminar ft'ing keynote speaker Dr. Squire Booker. Learn more➡️ tinyurl.com/kpnetx9f
Reposted by Univ. of Pennsylvania Department of Cancer Biology
#ICYMI: Nominations for the @pennmedicine.bsky.social Awards of Excellence, which recognize our faculty's exceptional achievements in mentoring, professionalism, research & clinical work, are open through Friday, 6/20! Learn more➡️ bit.ly/3yAaduR #PSOMAOE
June 9, 2025 at 4:53 PM
#ICYMI: Nominations for the @pennmedicine.bsky.social Awards of Excellence, which recognize our faculty's exceptional achievements in mentoring, professionalism, research & clinical work, are open through Friday, 6/20! Learn more➡️ bit.ly/3yAaduR #PSOMAOE
Learn more about 2-PREVENT Breast Cancer Translational Center for Excellence led by @angiedemichele.bsky.social & @penncbio.bsky.social chair Lewis Chodosh to identify and treat dormant breast cancer to forestall recurrence.
Keeping cancer conquered ft. @angiedemichele.bsky.social, @AmaravadiRavi, Kevin Fox (@penncancer.bsky.social), Lewis Chodosh (@Penn_CBIO), Jerry Rosenbloom (@Wharton), Andrea Orsher & Robert Orsher (@Pennalumni) tinyurl.com/zxcb3eaj
June 10, 2025 at 1:08 PM
Learn more about 2-PREVENT Breast Cancer Translational Center for Excellence led by @angiedemichele.bsky.social & @penncbio.bsky.social chair Lewis Chodosh to identify and treat dormant breast cancer to forestall recurrence.
Reposted by Univ. of Pennsylvania Department of Cancer Biology
ft. Elizabeth McDonald, @DavidMankoff2, Robert Mach (@PennRadiology), Tien-Chi Pan, @dhruvk_pant & Lewis Chodosh (@penncbio.bsky.social/ @penncancer.bsky.social) aacrjournals.org/cancerrescom...
March 21, 2025 at 4:17 PM
ft. Elizabeth McDonald, @DavidMankoff2, Robert Mach (@PennRadiology), Tien-Chi Pan, @dhruvk_pant & Lewis Chodosh (@penncbio.bsky.social/ @penncancer.bsky.social) aacrjournals.org/cancerrescom...
Reposted by Univ. of Pennsylvania Department of Cancer Biology
#STATMadness voting is now open! Show your support for @pennmedicine.bsky.social's @StephenBagleyMD, @LogunMeghan, Zev Binder, @orourkedm & colleagues by voting to advance their study to the next round of competition! @PennNSG @penncancer.bsky.social @statnews.com tinyurl.com/yp2zbsce
March 4, 2025 at 6:15 PM
#STATMadness voting is now open! Show your support for @pennmedicine.bsky.social's @StephenBagleyMD, @LogunMeghan, Zev Binder, @orourkedm & colleagues by voting to advance their study to the next round of competition! @PennNSG @penncancer.bsky.social @statnews.com tinyurl.com/yp2zbsce
Reposted by Univ. of Pennsylvania Department of Cancer Biology
Snapshots of acyl carrier protein shuttling in human fatty acid synthase ft. @kschultzy.bsky.social, Pedro Costa-Pinheiro, Lauren Gardner, @laura_vpinheiro, Julio Ramirez-Solis, Sarah Gardner, @WellenLab & @MarmorsteinLab @penncancer.bsky.social @BB_UPenn @Penn_CBIO www.nature.com/articles/s41...
March 7, 2025 at 1:39 PM
Snapshots of acyl carrier protein shuttling in human fatty acid synthase ft. @kschultzy.bsky.social, Pedro Costa-Pinheiro, Lauren Gardner, @laura_vpinheiro, Julio Ramirez-Solis, Sarah Gardner, @WellenLab & @MarmorsteinLab @penncancer.bsky.social @BB_UPenn @Penn_CBIO www.nature.com/articles/s41...
We're excited to launch the official BlueSky account of the Department of Cancer Biology @pennmedicine.bsky.social. Stay tuned for our upcoming faculty search ad, highlights from our published research discoveries, and other departmental news! med.upenn.edu/cbio/
med.upenn.edu
March 9, 2025 at 1:30 PM
We're excited to launch the official BlueSky account of the Department of Cancer Biology @pennmedicine.bsky.social. Stay tuned for our upcoming faculty search ad, highlights from our published research discoveries, and other departmental news! med.upenn.edu/cbio/