Pedro Saavedra
@pedrosvdr.bsky.social
Assist. Professor at Northeastern University (https://www.saavedralab.com) | Postdoc @MSKCancerCenter | PhD @UGent @InflamResCen | Host-microbe interactions and cell death. 🇧🇷
Very excited to share my lab's first publication in the format of a minireview at @asm.org mBio! Here, we discuss the historical context and current understanding of host immunity to C. difficile infection. #immunology
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
The interplay between host immunity and Clostridioides difficile infection | mBio
Clostridioides difficile is a gram-positive, toxin-producing, and spore-forming, anaerobic bacterium. C. difficile infection (CDI) is a major public health concern and one of the leading causes of
hea...
journals.asm.org
July 1, 2025 at 4:39 PM
Very excited to share my lab's first publication in the format of a minireview at @asm.org mBio! Here, we discuss the historical context and current understanding of host immunity to C. difficile infection. #immunology
journals.asm.org/doi/10.1128/...
journals.asm.org/doi/10.1128/...
Reposted by Pedro Saavedra
Given the SCOTUS ruling yesterday, it's seems possible....even highly likely....that the NIH IDC ruling will now only apply to the states that filed. If you're in a red state, that means 15% IDCs might be a reality soon.
June 28, 2025 at 11:38 AM
Given the SCOTUS ruling yesterday, it's seems possible....even highly likely....that the NIH IDC ruling will now only apply to the states that filed. If you're in a red state, that means 15% IDCs might be a reality soon.
Reposted by Pedro Saavedra
How bad will it be? Catastrophic.
Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come.
But, this is the WH's *proposed* budget.
Speak up now before it is too late.
(inflation adjusted $-s below)
Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come.
But, this is the WH's *proposed* budget.
Speak up now before it is too late.
(inflation adjusted $-s below)
May 31, 2025 at 2:50 AM
Reposted by Pedro Saavedra
Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans.
Email or DM me to find out more. Please share & repost!
Email or DM me to find out more. Please share & repost!
Postdoctoral Research Associate, Biology
About the Opportunity Job Summary The Apfeld Lab at Northeastern University is seeking a postdoctoral researcher to investigate how genes work together to determine the maximum lifespan of the nematod...
northeastern.wd1.myworkdayjobs.com
April 29, 2025 at 8:54 PM
Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans.
Email or DM me to find out more. Please share & repost!
Email or DM me to find out more. Please share & repost!
Reposted by Pedro Saavedra
In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
www.forbes.com
March 13, 2025 at 12:55 AM
In 2024 NIH grant awards supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. www.forbes.com/sites/michae...
Reposted by Pedro Saavedra
Tom Maniatis coming in hot in @CellCellPress
to spell out in no uncertain terms what cutting indirect cost rates to 15% will cost science.
And a call to action: "A united front...is essential to preventing this devastating policy from taking effect." 💯
www.cell.com/cell/fulltex...
to spell out in no uncertain terms what cutting indirect cost rates to 15% will cost science.
And a call to action: "A united front...is essential to preventing this devastating policy from taking effect." 💯
www.cell.com/cell/fulltex...
Safeguarding the future of biomedical science in the United States
NIH’s abrupt decision to cap indirect cost reimbursement at 15% threatens the critical
infrastructure supporting groundbreaking biomedical research in the United States.
This policy jeopardizes Americ...
www.cell.com
March 1, 2025 at 9:29 PM
Tom Maniatis coming in hot in @CellCellPress
to spell out in no uncertain terms what cutting indirect cost rates to 15% will cost science.
And a call to action: "A united front...is essential to preventing this devastating policy from taking effect." 💯
www.cell.com/cell/fulltex...
to spell out in no uncertain terms what cutting indirect cost rates to 15% will cost science.
And a call to action: "A united front...is essential to preventing this devastating policy from taking effect." 💯
www.cell.com/cell/fulltex...
Reposted by Pedro Saavedra
JUST IN: A federal judge in Massachusetts has blocked the Trump administration's rate change to NIH grants.
storage.courtlistener.com/recap/gov.us...
storage.courtlistener.com/recap/gov.us...
February 10, 2025 at 10:25 PM
JUST IN: A federal judge in Massachusetts has blocked the Trump administration's rate change to NIH grants.
storage.courtlistener.com/recap/gov.us...
storage.courtlistener.com/recap/gov.us...
Reposted by Pedro Saavedra
Attorney General Andrea Campbell of Massachusetts sued the Trump administration, alongside 21 other states, over its efforts to drastically reduce federal funding for biomedical research.
Mass. and 21 other states sue Trump administration over NIH research funding cuts - The Boston Globe
The lawsuit, filed Monday in U.S. District Court for Massachusetts, was co-led by Campbell and asserts that the Trump administration’s changes violate the Administrative Procedure Act.
www.bostonglobe.com
February 10, 2025 at 6:05 PM
Attorney General Andrea Campbell of Massachusetts sued the Trump administration, alongside 21 other states, over its efforts to drastically reduce federal funding for biomedical research.
Reposted by Pedro Saavedra
Executive wants to frame the NIH indirects cut as $4B in savings.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
Direct Economic Contributions
NIH directly supports the economy through investments in research institutions and job formation.
www.nih.gov
February 8, 2025 at 3:08 AM
Executive wants to frame the NIH indirects cut as $4B in savings.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
But given that NIH returns $2.5 on every $1 investment, this would actually cost US economy a net $6 BILLION (per year!). Not to mention the human costs of wrecking education and research sectors and the communities they serve.
Reposted by Pedro Saavedra
This is a list of blockbuster drugs in 2024. Guess how many can trace their origins to NIH funded research?
All of them.
All of them.
February 8, 2025 at 4:09 AM
This is a list of blockbuster drugs in 2024. Guess how many can trace their origins to NIH funded research?
All of them.
All of them.
Reposted by Pedro Saavedra
Research universities are often the largest employers in their region. They are often the primary health care providers to communities. This funding shift will not only reduce US research leadership, it will put working people out of work and reduce healthcare access.
Excellent 🧵 on this evening's NIH announcement of a dramatic reduction in indirect rates for research institutions, which amounts to a generational restructuring of the US research and development ecosystem. These cuts are effective immediately, not just for new grants but for existing ones.
6. The policy does not just affect funding going forward. All existing NIH grants will have their indirect rates cut to 15% as of today, the date of issuance.
For a large university, this creates a sudden and catastrophic shortfall of hundreds of millions of dollars against already budgeted funds.
For a large university, this creates a sudden and catastrophic shortfall of hundreds of millions of dollars against already budgeted funds.
February 8, 2025 at 1:40 AM
Research universities are often the largest employers in their region. They are often the primary health care providers to communities. This funding shift will not only reduce US research leadership, it will put working people out of work and reduce healthcare access.