I created this image using BioRender.
It's my attempt to depict Mitochondrial Dysfunction and the ROS-induced reversal of the Sodium /Calcium Exchanger in the Skeletal Muscle Cells of ME/cfs patients, as described by Klaus Wirth and Prof. Carmen Scheibenbogen.
#Mitochondria #MEcfs #LongCovid

This is what happens in the Skeletal Muscles of #MEcfs patients.
Reversal of the Sodium/ Calcium Exchanger represents a profound step in the pathological process
Listen to Klaus Wirth describe what he & @scheibenbogen.bsky.social discovered & the drug he's developing:
www.youtube.com/watch?v=LzGG...

Prusty's "The Enemy within" paper, established a virally-driven model of autoimmunity, showing how non-canonical viral peptides trigger persistent immune activation.
Here, ncRNA-derived peptides & EV-mediated antigen presentation are presented as additional mechanisms of immune dysregulation.
#MEcfs