paulmoodyoxford.bsky.social
@paulmoodyoxford.bsky.social
Reposted by paulmoodyoxford.bsky.social
Scaling down protein language modeling with MSA Pairformer https://www.biorxiv.org/content/10.1101/2025.08.02.668173v1
August 4, 2025 at 3:48 AM
Scaling down protein language modeling with MSA Pairformer https://www.biorxiv.org/content/10.1101/2025.08.02.668173v1
Reposted by paulmoodyoxford.bsky.social
If you’re doing DNA barcoding in a fieldwork or resource-limited context and you want to improve phylogenetic resolution at lower cost, here’s a method that allows the sequencing of 3 unlinked regions using long amplicon PCR and @nanoporetech.com MinION for ~€5 a sample.
📷 Timothy Dykes
📷 Timothy Dykes
December 19, 2024 at 12:16 PM
If you’re doing DNA barcoding in a fieldwork or resource-limited context and you want to improve phylogenetic resolution at lower cost, here’s a method that allows the sequencing of 3 unlinked regions using long amplicon PCR and @nanoporetech.com MinION for ~€5 a sample.
📷 Timothy Dykes
📷 Timothy Dykes
Reposted by paulmoodyoxford.bsky.social
🎄 New Dorado release (v0.9.0) – and it's big!
🚀 Dorado polish command (experimental) for improving draft assemblies – faster & more accurate than Medaka
⚡ Faster modified base calling models
🔧 Usability & accuracy improvements: PolyA, Barcoding, 6mA calling
github.com/nanoporetech...
🚀 Dorado polish command (experimental) for improving draft assemblies – faster & more accurate than Medaka
⚡ Faster modified base calling models
🔧 Usability & accuracy improvements: PolyA, Barcoding, 6mA calling
github.com/nanoporetech...
Release v0.9.0 · nanoporetech/dorado
[0.9.0] (16 Dec 2024)
This major release of Dorado introduces several new features and enhancements. The polish command, currently experimental, is optimised for refining draft assemblies of human ...
github.com
December 17, 2024 at 11:59 AM
🎄 New Dorado release (v0.9.0) – and it's big!
🚀 Dorado polish command (experimental) for improving draft assemblies – faster & more accurate than Medaka
⚡ Faster modified base calling models
🔧 Usability & accuracy improvements: PolyA, Barcoding, 6mA calling
github.com/nanoporetech...
🚀 Dorado polish command (experimental) for improving draft assemblies – faster & more accurate than Medaka
⚡ Faster modified base calling models
🔧 Usability & accuracy improvements: PolyA, Barcoding, 6mA calling
github.com/nanoporetech...
Reposted by paulmoodyoxford.bsky.social
Our Big Fantastic Virus Database (BFVD) is now published NAR! It contains protein structure predictions of major viral clades, enhanced by petabase-scale homology search and it's explorable on the web.
🌐 bfvd.foldseek.com
💾 bfvd.steineggerlab.workers.dev
📄 academic.oup.com/nar/advance-...
🌐 bfvd.foldseek.com
💾 bfvd.steineggerlab.workers.dev
📄 academic.oup.com/nar/advance-...
November 23, 2024 at 9:12 PM
Our Big Fantastic Virus Database (BFVD) is now published NAR! It contains protein structure predictions of major viral clades, enhanced by petabase-scale homology search and it's explorable on the web.
🌐 bfvd.foldseek.com
💾 bfvd.steineggerlab.workers.dev
📄 academic.oup.com/nar/advance-...
🌐 bfvd.foldseek.com
💾 bfvd.steineggerlab.workers.dev
📄 academic.oup.com/nar/advance-...
Reposted by paulmoodyoxford.bsky.social
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
November 17, 2024 at 4:20 PM
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
Oxford Nanopore sequencing classifies tumours mid-surgery (COI - I work for Oxford Nanopore)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Ultra-fast deep-learned CNS tumour classification during surgery - Nature
Sturgeon is a pretrained neural network that uses incremental results from nanopore sequencing to rapidly classify central nervous system tumours and can be used to aid critical decision-making during...
www.nature.com
October 11, 2023 at 5:30 PM
Oxford Nanopore sequencing classifies tumours mid-surgery (COI - I work for Oxford Nanopore)
www.nature.com/articles/s41...
www.nature.com/articles/s41...