Patrik Rödin Mörch
@patrikrodinmorch.bsky.social
Genomics, evolution, conservation. Post-doc at Uppsala University.
Reposted by Patrik Rödin Mörch
One month later and those 30 billion base pairs are crammed into just about 14 chromosomes. HOT DANG! This seemed impossible 4-5 years ago.
Genome assembly fresh of the supercomputer, total size = 29,892,519,935 base pairs 🦎🧬
November 26, 2025 at 3:58 PM
One month later and those 30 billion base pairs are crammed into just about 14 chromosomes. HOT DANG! This seemed impossible 4-5 years ago.
Reposted by Patrik Rödin Mörch
Just over a month left to apply for scholarships on this project. We will run internal pre-selection interviews end of November, so if you consider applying, please reach out now. I can guarantee amazing scientific and intellectual environment at the Institute for Eco Evo @edinburghup.bsky.social
If you like genomics, speciation, and primates, this PhD position is for you! Unraveling the genomic architecture of speciation and gene flow in guenons, a diverse group of African monkeys. Funding through DTP. Do reach out with questions! #genomics #genome_assembly
evol.mcmaster.ca/brian/evoldi...
evol.mcmaster.ca/brian/evoldi...
November 5, 2025 at 10:01 AM
Just over a month left to apply for scholarships on this project. We will run internal pre-selection interviews end of November, so if you consider applying, please reach out now. I can guarantee amazing scientific and intellectual environment at the Institute for Eco Evo @edinburghup.bsky.social
Reposted by Patrik Rödin Mörch
I am thrilled to share this paper outlining some ideas I’ve been thinking about for a little while on a simple but powerful approach for predicting risk of inbreeding depression from long runs of homozygosity and non-ROH heterozygosity. 1/n @klohmueller.bsky.social doi.org/10.1016/j.tr...
August 4, 2025 at 5:10 PM
I am thrilled to share this paper outlining some ideas I’ve been thinking about for a little while on a simple but powerful approach for predicting risk of inbreeding depression from long runs of homozygosity and non-ROH heterozygosity. 1/n @klohmueller.bsky.social doi.org/10.1016/j.tr...
Reposted by Patrik Rödin Mörch
Happy to share that our Perspective on how genome editing could restore lost diversity and help species adapt to climate or disease is out in @natrevbiodiv.nature.com
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity
Genome engineering in biodiversity conservation and restoration - Nature Reviews Biodiversity
This Perspective argues for the use of genome engineering for restoring species genetic diversity and increase species resilience to environmental change. Genome engineering could be combined with tra...
tinyurl.com
July 18, 2025 at 12:23 PM
Happy to share that our Perspective on how genome editing could restore lost diversity and help species adapt to climate or disease is out in @natrevbiodiv.nature.com
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity
Reposted by Patrik Rödin Mörch
Super excited for this chance to share our @biorxivpreprint.bsky.social #preprint, in wihch we ask a simple question – what were the genomic of gorillas evolving polygyny?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
July 1, 2025 at 12:48 PM
Super excited for this chance to share our @biorxivpreprint.bsky.social #preprint, in wihch we ask a simple question – what were the genomic of gorillas evolving polygyny?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Patrik Rödin Mörch
(1/2) 🦋 The Atlas Blue butterfly has a staggering 229 chromosomes—far beyond the usual 31–32 in most moths and butterflies! 🧬
Join EBP trailblazer Mark Blaxter and the @sangerinstitute.bsky.social team as they tackle the challenge of assembling them all.
👉learn more: bit.ly/3TIXLSU
📸 M. Harzallah
Join EBP trailblazer Mark Blaxter and the @sangerinstitute.bsky.social team as they tackle the challenge of assembling them all.
👉learn more: bit.ly/3TIXLSU
📸 M. Harzallah
June 30, 2025 at 4:15 PM
(1/2) 🦋 The Atlas Blue butterfly has a staggering 229 chromosomes—far beyond the usual 31–32 in most moths and butterflies! 🧬
Join EBP trailblazer Mark Blaxter and the @sangerinstitute.bsky.social team as they tackle the challenge of assembling them all.
👉learn more: bit.ly/3TIXLSU
📸 M. Harzallah
Join EBP trailblazer Mark Blaxter and the @sangerinstitute.bsky.social team as they tackle the challenge of assembling them all.
👉learn more: bit.ly/3TIXLSU
📸 M. Harzallah
Reposted by Patrik Rödin Mörch
📢 It’s time to harmonise practices for assessing genome-wide genetic diversity 🧬 Standardisation is key to meet the needs of stakeholders in biodiversity #conservation.
🔗 New publication by #ERGA
@biogeneurope.bsky.social out now in #MolecularEcology
onlinelibrary.wiley.com/doi/10.1111/...
🔗 New publication by #ERGA
@biogeneurope.bsky.social out now in #MolecularEcology
onlinelibrary.wiley.com/doi/10.1111/...
Biodiversity Genomics Research Practices Require Harmonising to Meet Stakeholder Needs in Conservation
Biodiversity resilience relies on genetic diversity, which sustains the evolutionary potential of organisms in dynamic ecosystems. Genomics is a powerful tool for accurately estimating genetic divers...
onlinelibrary.wiley.com
June 30, 2025 at 9:41 AM
📢 It’s time to harmonise practices for assessing genome-wide genetic diversity 🧬 Standardisation is key to meet the needs of stakeholders in biodiversity #conservation.
🔗 New publication by #ERGA
@biogeneurope.bsky.social out now in #MolecularEcology
onlinelibrary.wiley.com/doi/10.1111/...
🔗 New publication by #ERGA
@biogeneurope.bsky.social out now in #MolecularEcology
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Patrik Rödin Mörch
Only two more days to apply!! Put your name in the hat, even if you feel like you don't match all criteria listed. Happy to chat regardless!
🚨 Wanted: PhD student excited about population genomics, Natural History Collections and birds!
📍 Museum für Naturkunde, Berlin, Germany
🕒 3 Years, fully funded by the Leibniz Junior Researchgroup program
Details and Application portal 👇
jobs.museumfuernaturkunde.berlin/jobposting/8...
📍 Museum für Naturkunde, Berlin, Germany
🕒 3 Years, fully funded by the Leibniz Junior Researchgroup program
Details and Application portal 👇
jobs.museumfuernaturkunde.berlin/jobposting/8...
14/2025 PhD student (f/m/d)
jobs.museumfuernaturkunde.berlin
June 9, 2025 at 9:55 AM
Only two more days to apply!! Put your name in the hat, even if you feel like you don't match all criteria listed. Happy to chat regardless!
Reposted by Patrik Rödin Mörch
Interested in measuring genetic load? We have a new paper out providing a modified version of GERP which is more user friendly in wildlife species and with scripts to automate making input files and pulling out derived alleles in your species #consgen #popgen star-protocols.cell.com/protocols/4202
Cell Press: STAR Protocols
STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all are...
star-protocols.cell.com
May 21, 2025 at 1:12 PM
Interested in measuring genetic load? We have a new paper out providing a modified version of GERP which is more user friendly in wildlife species and with scripts to automate making input files and pulling out derived alleles in your species #consgen #popgen star-protocols.cell.com/protocols/4202
Reposted by Patrik Rödin Mörch
Finally out: Predicting adaptation to climate warming www.nature.com/articles/s41...
We find that there are many genomic routes to heat-adaptation, but this can also make genomic data of limited value for prediction. A tour de force by @denovorego.bsky.social , with @stelkens.bsky.social.
We find that there are many genomic routes to heat-adaptation, but this can also make genomic data of limited value for prediction. A tour de force by @denovorego.bsky.social , with @stelkens.bsky.social.
Repeatability of evolution and genomic predictions of temperature adaptation in seed beetles - Nature Ecology & Evolution
The authors compare genomic and phenotypic changes between genetic backgrounds of seed beetles evolved at hot or cold temperatures. Despite phenotypic changes being more rapid and predictable at hot t...
www.nature.com
May 16, 2025 at 12:16 PM
Finally out: Predicting adaptation to climate warming www.nature.com/articles/s41...
We find that there are many genomic routes to heat-adaptation, but this can also make genomic data of limited value for prediction. A tour de force by @denovorego.bsky.social , with @stelkens.bsky.social.
We find that there are many genomic routes to heat-adaptation, but this can also make genomic data of limited value for prediction. A tour de force by @denovorego.bsky.social , with @stelkens.bsky.social.
Reposted by Patrik Rödin Mörch
Reposted by Patrik Rödin Mörch
Struggling to find the tiny microchromosomes in draft bird genome assemblies?
Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1...
🧵 below
(1/n)
@sangerinstitute.bsky.social
Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1...
🧵 below
(1/n)
@sangerinstitute.bsky.social
May 16, 2025 at 10:07 AM
Struggling to find the tiny microchromosomes in draft bird genome assemblies?
Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1...
🧵 below
(1/n)
@sangerinstitute.bsky.social
Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1...
🧵 below
(1/n)
@sangerinstitute.bsky.social
Reposted by Patrik Rödin Mörch
Great to see our latest paper on Ngorongoro Crater lion genomics out @commsbio.bsky.social
Even after a rapid post-epizootic recovery in the 1970s, habitat fragmentation and continued isolation led to an increase in genetic load and to a reduction in overall genetic variation.
Even after a rapid post-epizootic recovery in the 1970s, habitat fragmentation and continued isolation led to an increase in genetic load and to a reduction in overall genetic variation.
April 21, 2025 at 6:07 PM
Great to see our latest paper on Ngorongoro Crater lion genomics out @commsbio.bsky.social
Even after a rapid post-epizootic recovery in the 1970s, habitat fragmentation and continued isolation led to an increase in genetic load and to a reduction in overall genetic variation.
Even after a rapid post-epizootic recovery in the 1970s, habitat fragmentation and continued isolation led to an increase in genetic load and to a reduction in overall genetic variation.
Reposted by Patrik Rödin Mörch
🚨 New preprint!
We analyzed 39 bird genomes—including 3 Mauritian species that bounced back from the brink of extinction—to explore genomic erosion in a comparative framework.
🧬🦜🧩
📄 www.biorxiv.org/content/10.1...
#consgen #popgen
@claudiafontsere.bsky.social
We analyzed 39 bird genomes—including 3 Mauritian species that bounced back from the brink of extinction—to explore genomic erosion in a comparative framework.
🧬🦜🧩
📄 www.biorxiv.org/content/10.1...
#consgen #popgen
@claudiafontsere.bsky.social
April 10, 2025 at 3:04 PM
🚨 New preprint!
We analyzed 39 bird genomes—including 3 Mauritian species that bounced back from the brink of extinction—to explore genomic erosion in a comparative framework.
🧬🦜🧩
📄 www.biorxiv.org/content/10.1...
#consgen #popgen
@claudiafontsere.bsky.social
We analyzed 39 bird genomes—including 3 Mauritian species that bounced back from the brink of extinction—to explore genomic erosion in a comparative framework.
🧬🦜🧩
📄 www.biorxiv.org/content/10.1...
#consgen #popgen
@claudiafontsere.bsky.social
Reposted by Patrik Rödin Mörch
I feel honored that our work: "On the origin of an insular hybrid butterfly lineage" was picked as "Editor's choice" and that my picture of a mating couple (🧡🤎) covers the latest issue of Evolution @journal-evo.bsky.social. Link to paper: academic.oup.com/evolut/artic... (1/8)
April 3, 2025 at 2:38 PM
I feel honored that our work: "On the origin of an insular hybrid butterfly lineage" was picked as "Editor's choice" and that my picture of a mating couple (🧡🤎) covers the latest issue of Evolution @journal-evo.bsky.social. Link to paper: academic.oup.com/evolut/artic... (1/8)
Reposted by Patrik Rödin Mörch
📢 NEW GENOME ALERT
In #G3journal, Rödin-Mörch et al. generated a high-quality reference genome of the European green toad to understand the evolutionary genomics of the amphibian.
Read more: buff.ly/XnaKB29
In #G3journal, Rödin-Mörch et al. generated a high-quality reference genome of the European green toad to understand the evolutionary genomics of the amphibian.
Read more: buff.ly/XnaKB29
April 3, 2025 at 4:00 PM
📢 NEW GENOME ALERT
In #G3journal, Rödin-Mörch et al. generated a high-quality reference genome of the European green toad to understand the evolutionary genomics of the amphibian.
Read more: buff.ly/XnaKB29
In #G3journal, Rödin-Mörch et al. generated a high-quality reference genome of the European green toad to understand the evolutionary genomics of the amphibian.
Read more: buff.ly/XnaKB29
Reposted by Patrik Rödin Mörch
PhD position on Evolution of Seasonal Camouflage in my group. Fully funded 4 year position in Stockholm University and SciLifeLab! :-)
su.varbi.com/en/what:job/...
su.varbi.com/en/what:job/...
PhD Student in Evolution of Seasonal Camouflage
The Department of Zoology at Stockholm University includes about 80 employeese, including Researchers, PhD students and administrative staff. Research and education at the department occurs in an inte
su.varbi.com
April 2, 2025 at 11:41 AM
PhD position on Evolution of Seasonal Camouflage in my group. Fully funded 4 year position in Stockholm University and SciLifeLab! :-)
su.varbi.com/en/what:job/...
su.varbi.com/en/what:job/...
Reposted by Patrik Rödin Mörch
The orange-bellied parrot is predicted to go extinct by 2038. We tracked >200 years of genomic erosion. Here’s what we found 🧬🦜 #ConservationGenomics #consgen #popgen
onlinelibrary.wiley.com/doi/10.1111/...
pic by Marc Gardner
onlinelibrary.wiley.com/doi/10.1111/...
pic by Marc Gardner
March 31, 2025 at 3:51 PM
The orange-bellied parrot is predicted to go extinct by 2038. We tracked >200 years of genomic erosion. Here’s what we found 🧬🦜 #ConservationGenomics #consgen #popgen
onlinelibrary.wiley.com/doi/10.1111/...
pic by Marc Gardner
onlinelibrary.wiley.com/doi/10.1111/...
pic by Marc Gardner
Reposted by Patrik Rödin Mörch
🧬🌍 Happy to see our latest paper out at @royalsocietypublishing.org
We show how genetic risks in endangered species can stay hidden due to a time-lag between demographic collapse and genetic loss. Work led by amazing MSc students Xufen Liu and Ester Milesi #ConservationGenomics
Pic by David Stowe
We show how genetic risks in endangered species can stay hidden due to a time-lag between demographic collapse and genetic loss. Work led by amazing MSc students Xufen Liu and Ester Milesi #ConservationGenomics
Pic by David Stowe
March 27, 2025 at 4:57 PM
🧬🌍 Happy to see our latest paper out at @royalsocietypublishing.org
We show how genetic risks in endangered species can stay hidden due to a time-lag between demographic collapse and genetic loss. Work led by amazing MSc students Xufen Liu and Ester Milesi #ConservationGenomics
Pic by David Stowe
We show how genetic risks in endangered species can stay hidden due to a time-lag between demographic collapse and genetic loss. Work led by amazing MSc students Xufen Liu and Ester Milesi #ConservationGenomics
Pic by David Stowe
Reposted by Patrik Rödin Mörch
Dental calculus, the preserved oral microbiome, is an absolute treasure trove of information that can be interrogated across thousands of years. But how to make it work? In a new preprint, @markella-morait.bsky.social asks this questions using >30 mammalian species:
doi.org/10.1101/2025...
March 25, 2025 at 6:17 PM
Dental calculus, the preserved oral microbiome, is an absolute treasure trove of information that can be interrogated across thousands of years. But how to make it work? In a new preprint, @markella-morait.bsky.social asks this questions using >30 mammalian species:
doi.org/10.1101/2025...
Reposted by Patrik Rödin Mörch
stdpopsim v0.3.0 is out! You can now mix and match your simulations of different demographic histories with published distributions of fitness effects along with gene annotations, and you can even throw in sweeps for good measure. Check out the new manuscript for more info: doi.org/10.1101/2025...
Accessible, realistic genome simulation with selection using stdpopsim
Selection is a fundamental evolutionary force that shapes patterns of genetic variation across species. However, simulations incorporating realistic selection along heterogeneous genomes in complex de...
doi.org
March 24, 2025 at 6:29 PM
stdpopsim v0.3.0 is out! You can now mix and match your simulations of different demographic histories with published distributions of fitness effects along with gene annotations, and you can even throw in sweeps for good measure. Check out the new manuscript for more info: doi.org/10.1101/2025...
Reposted by Patrik Rödin Mörch
BWA-0.7.19 released with a fix to the internal HD-line bug introduced in 0.7.18
March 24, 2025 at 4:00 PM
BWA-0.7.19 released with a fix to the internal HD-line bug introduced in 0.7.18
Reposted by Patrik Rödin Mörch
Our latest paper revisits Haldane 1957 on speed limits to adaptation, the paper that triggered neutral theory. We clarify and then significantly extend the theory, and apply the resulting model to @mexpositoalonso.bsky.social's data doi.org/10.1093/gene... 1/14
Substitution load revisited: a high proportion of deaths can be selective
Abstract. Haldane's Dilemma refers to the concern that the need for many “selective deaths” to complete a substitution (i.e. selective sweep) creates a spe
doi.org
March 19, 2025 at 10:58 PM
Our latest paper revisits Haldane 1957 on speed limits to adaptation, the paper that triggered neutral theory. We clarify and then significantly extend the theory, and apply the resulting model to @mexpositoalonso.bsky.social's data doi.org/10.1093/gene... 1/14
Reposted by Patrik Rödin Mörch
A chromosome-level genome assembly of the European green toad (Bufotes viridis)
Published yesterday in G3
@GeneticsGSA
Published yesterday in G3
@GeneticsGSA
March 19, 2025 at 7:22 AM
A chromosome-level genome assembly of the European green toad (Bufotes viridis)
Published yesterday in G3
@GeneticsGSA
Published yesterday in G3
@GeneticsGSA
Reposted by Patrik Rödin Mörch
[Please share widely]
Come work at the U. of Oslo. We are advertising a 3-year postdoc in Evolutionary and Comparative Genomics. If working with plant evolution in the Galápagos, pangenome and structural variants sounds exciting for you - this may be your chance!
www.jobbnorge.no/en/available...
Come work at the U. of Oslo. We are advertising a 3-year postdoc in Evolutionary and Comparative Genomics. If working with plant evolution in the Galápagos, pangenome and structural variants sounds exciting for you - this may be your chance!
www.jobbnorge.no/en/available...
Postdoctoral Research Fellow in Evolutionary and Comparative Genomics (277333) | University of Oslo
Job title: Postdoctoral Research Fellow in Evolutionary and Comparative Genomics (277333), Employer: University of Oslo, Deadline: Wednesday, April 9, 2025
www.jobbnorge.no
March 19, 2025 at 9:52 AM
[Please share widely]
Come work at the U. of Oslo. We are advertising a 3-year postdoc in Evolutionary and Comparative Genomics. If working with plant evolution in the Galápagos, pangenome and structural variants sounds exciting for you - this may be your chance!
www.jobbnorge.no/en/available...
Come work at the U. of Oslo. We are advertising a 3-year postdoc in Evolutionary and Comparative Genomics. If working with plant evolution in the Galápagos, pangenome and structural variants sounds exciting for you - this may be your chance!
www.jobbnorge.no/en/available...