Folddisco detects (partial) motifs, allowing for substitutions and angle-length variations, by utilizing an index storing all residue pairs within 20Å encoded as geometric features. For space efficiency, it omits positions and compresses ids through run-length encoding (1.4TB for 53M structures) 2/9

Thanks Jim for this Alert. About XL-MS mapping using our tool XMAS: in fig 2C you are plotting the same restraint multiple times (aligned grey dots). To avoid this and show only the shortest in the oligomer you can hit “analyze>find shortest>0Å difference” (default cutoff is 2Å). Cheers :)