Colin Scott
@oz-biocat.bsky.social
Australian microbial biochemist, synthetic biologist and protein engineer. CSO at ULUU. Interests in biotech solutions to pollution, resource scarcity, and sustainable manufacture.
Pinned
Colin Scott
@oz-biocat.bsky.social
· Dec 20
Uluu
Uluu replaces plastic with materials that are good for the world. Our products act like plastic but are made from seaweed, not fossil fuels. They’re biodegradable and climate positive.
www.uluu.com.au
I'm thrilled to announce my new role as the Head of Enzyme Engineering at the innovative biotech startup Uluu (www.uluu.com.au), in Perth, Western Australia. I'm delighted to have the opportunity to support Uluu in making a step change in industrial biotechnology in Australia.
PFAS are generally regarded as concerning.
Identifying and engineering defluorinases to degrade them is difficult, partly because there are few HTP assays to track defluorination.
Here, we demonstrate a riboswitch based HTP assay for fluoride release - hope it helps!
lnkd.in/gnMMbVfh
Identifying and engineering defluorinases to degrade them is difficult, partly because there are few HTP assays to track defluorination.
Here, we demonstrate a riboswitch based HTP assay for fluoride release - hope it helps!
lnkd.in/gnMMbVfh
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
October 14, 2025 at 1:11 AM
PFAS are generally regarded as concerning.
Identifying and engineering defluorinases to degrade them is difficult, partly because there are few HTP assays to track defluorination.
Here, we demonstrate a riboswitch based HTP assay for fluoride release - hope it helps!
lnkd.in/gnMMbVfh
Identifying and engineering defluorinases to degrade them is difficult, partly because there are few HTP assays to track defluorination.
Here, we demonstrate a riboswitch based HTP assay for fluoride release - hope it helps!
lnkd.in/gnMMbVfh
Working at ULUU is incredible - we're turning our scientific smarts into real-world impacts! Here's our most recent partnership with fashion brand Papinelle, featuring the replacement of plastic buttons with ULUU's biodegradable, bioderived alternative.
www.linkedin.com/posts/uluu_f...
www.linkedin.com/posts/uluu_f...
From seaweed to sleepwear 🌊✨
We’re excited to announce a new partnership with sleepwear brand Papinelle, launching beautiful pyjamas featuring ‘Made with Uluu’ buttons.
This brings our innovative… |...
From seaweed to sleepwear 🌊✨
We’re excited to announce a new partnership with sleepwear brand Papinelle, launching beautiful pyjamas featuring ‘Made with Uluu’ buttons.
This brings our innovative ma...
www.linkedin.com
September 27, 2025 at 3:48 AM
Working at ULUU is incredible - we're turning our scientific smarts into real-world impacts! Here's our most recent partnership with fashion brand Papinelle, featuring the replacement of plastic buttons with ULUU's biodegradable, bioderived alternative.
www.linkedin.com/posts/uluu_f...
www.linkedin.com/posts/uluu_f...
The most recent review from the Bioplastics Innovation Hub (Murdoch Uni/CSIRO) is available at Biotechnology Advances
www.sciencedirect.com/science/arti...
A review of the industrialisation of salt-loving Haloferacaceae. Congratulations @danagriffiths.bsky.social, Daniel Murphy, and Ravi Tiwari.
www.sciencedirect.com/science/arti...
A review of the industrialisation of salt-loving Haloferacaceae. Congratulations @danagriffiths.bsky.social, Daniel Murphy, and Ravi Tiwari.
Haloferax and the Haloferacaceae: Potential role in bioindustry
Members of the Haloferacaceae, a family of extremely halophilic archaea, exhibit unique physiological and genetic traits that make them promising cand…
www.sciencedirect.com
July 30, 2025 at 4:04 AM
The most recent review from the Bioplastics Innovation Hub (Murdoch Uni/CSIRO) is available at Biotechnology Advances
www.sciencedirect.com/science/arti...
A review of the industrialisation of salt-loving Haloferacaceae. Congratulations @danagriffiths.bsky.social, Daniel Murphy, and Ravi Tiwari.
www.sciencedirect.com/science/arti...
A review of the industrialisation of salt-loving Haloferacaceae. Congratulations @danagriffiths.bsky.social, Daniel Murphy, and Ravi Tiwari.
Happy to post this review on carbon biomineralisation - the energetically favorable formation of mineral carbonates, potentially removing it irreversibly from the biological carbon cycle
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Harnessing the biomolecular mechanisms of marine biomineralisation for carbon sequestration
Anthropogenic activities, primarily fossil fuel combustion, have increased atmospheric carbon dioxide (CO2) levels and climate change effects. Carbon …
www.sciencedirect.com
July 19, 2025 at 2:27 AM
Happy to post this review on carbon biomineralisation - the energetically favorable formation of mineral carbonates, potentially removing it irreversibly from the biological carbon cycle
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Views from our holiday rental - a little upstream of Jervis Bay
July 17, 2025 at 7:57 AM
Views from our holiday rental - a little upstream of Jervis Bay
We know that immobilizing enzymes enhances their stability. The same is true for cofactors! Here we share our latest research, a collaboration with David Lewis' group at Flinders University. This work could lead to innovative applications in enzyme technology.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Enhanced Thermal Stability of NADH/NAD+ through Tethering to Silica Nanoparticles
The poor thermal stability of the cofactor β-nicotinamide adenine dinucleotide (NAD+) in industrial settings can be a limiting factor in the expansion of biosynthetic approaches to chemical production...
pubs.acs.org
June 6, 2025 at 4:23 AM
We know that immobilizing enzymes enhances their stability. The same is true for cofactors! Here we share our latest research, a collaboration with David Lewis' group at Flinders University. This work could lead to innovative applications in enzyme technology.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Coogee - 10 minutes from my apartment and a lovely place for a bit of a walk (or swim, or snorkel, or fish)
February 16, 2025 at 12:16 PM
Coogee - 10 minutes from my apartment and a lovely place for a bit of a walk (or swim, or snorkel, or fish)
My new office- not a bad location
February 12, 2025 at 3:54 AM
My new office- not a bad location
Our most recent paper has just landed. In an exciting collaboration with the world leading Alexandrov biosensor lab at QUT we’ve developed a new specific and selective sensor for rare earth elements.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Lanthanide‐controlled protein switches: development and in vitro and in vivo applications
Lanthanides, which are part of the rare earth elements group have numerous applications in electronics, medicine and energy storage. However, our ability to extract them is not meeting the rapidly i....
onlinelibrary.wiley.com
January 30, 2025 at 7:38 AM
Our most recent paper has just landed. In an exciting collaboration with the world leading Alexandrov biosensor lab at QUT we’ve developed a new specific and selective sensor for rare earth elements.
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Colin Scott
Fancy working at the Australian Synchrotron for a little bit?
🧪
Please share with your crystal pals!
www.seek.com.au/synchrotron-...
🧪
Please share with your crystal pals!
www.seek.com.au/synchrotron-...
January 15, 2025 at 5:32 AM
Fancy working at the Australian Synchrotron for a little bit?
🧪
Please share with your crystal pals!
www.seek.com.au/synchrotron-...
🧪
Please share with your crystal pals!
www.seek.com.au/synchrotron-...
Great paper: www.nature.com/articles/s41...
A new-to-nature photosynthesis system enhances utilization of one-carbon substrates in Escherichia coli - Nature Communications
Engineering photosynthetic ability in non-photosynthetic microbes to assimilate one-carbon substrates remains challenging. Here, the authors construct a new-to-nature photosynthesis system in E. coli ...
www.nature.com
January 15, 2025 at 5:37 AM
Great paper: www.nature.com/articles/s41...
Reposted by Colin Scott
📢 In collaboration with @coeplantsuccess.bsky.social , we've launched Best Practice Guidelines for scientists working with genetic resources. #NagoyaProtocol
Take a look here ⬇️
www.coesb.com.au/research/nag...
Take a look here ⬇️
www.coesb.com.au/research/nag...
Nagoya Protocol Best Practice Guidelines
Best Practice Guidelines for the Collection and Transfer of Genetic ResourcesAustralian law in relation to the collection, transfer, and use of genetic resources is piecemeal, fragmented, and incomple...
www.coesb.com.au
January 14, 2025 at 10:35 PM
📢 In collaboration with @coeplantsuccess.bsky.social , we've launched Best Practice Guidelines for scientists working with genetic resources. #NagoyaProtocol
Take a look here ⬇️
www.coesb.com.au/research/nag...
Take a look here ⬇️
www.coesb.com.au/research/nag...
Reposted by Colin Scott
www.nature.com/articles/s42...
Paper on ASR protein ML published (congrats @danasmatthews.bsky.social and everyone else not on Bluesky). Some interesting bits - ASR can generate quality synthetic data, local sequence density important, and evo relationships can yield smoother fitness landscapes
Paper on ASR protein ML published (congrats @danasmatthews.bsky.social and everyone else not on Bluesky). Some interesting bits - ASR can generate quality synthetic data, local sequence density important, and evo relationships can yield smoother fitness landscapes
Leveraging ancestral sequence reconstruction for protein representation learning - Nature Machine Intelligence
Matthews et al. present a protein sequence embedding based on data from ancestral sequences that allows machine learning to be used for tasks where training data are scarce or expensive.
www.nature.com
December 19, 2024 at 4:54 AM
www.nature.com/articles/s42...
Paper on ASR protein ML published (congrats @danasmatthews.bsky.social and everyone else not on Bluesky). Some interesting bits - ASR can generate quality synthetic data, local sequence density important, and evo relationships can yield smoother fitness landscapes
Paper on ASR protein ML published (congrats @danasmatthews.bsky.social and everyone else not on Bluesky). Some interesting bits - ASR can generate quality synthetic data, local sequence density important, and evo relationships can yield smoother fitness landscapes
I'm thrilled to announce my new role as the Head of Enzyme Engineering at the innovative biotech startup Uluu (www.uluu.com.au), in Perth, Western Australia. I'm delighted to have the opportunity to support Uluu in making a step change in industrial biotechnology in Australia.
Uluu
Uluu replaces plastic with materials that are good for the world. Our products act like plastic but are made from seaweed, not fossil fuels. They’re biodegradable and climate positive.
www.uluu.com.au
December 20, 2024 at 3:25 AM
I'm thrilled to announce my new role as the Head of Enzyme Engineering at the innovative biotech startup Uluu (www.uluu.com.au), in Perth, Western Australia. I'm delighted to have the opportunity to support Uluu in making a step change in industrial biotechnology in Australia.
Our new paper that describes the structure and mechanism of a novel nitrohydrolase that breaks down explosives and confers resistance to an antituberculosis drug:
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Structural insights into the enzymatic breakdown of azomycin-derived antibiotics by 2-nitroimdazole hydrolase (NnhA) - Communications Biology
Experimentally determined structure of 2-nitroimidazole hydrolase and its comparison with other related enzymes shed light on the mechanism of action of an unusual antibiotic degrading enzyme in soil ...
www.nature.com
December 20, 2024 at 12:43 AM
Our new paper that describes the structure and mechanism of a novel nitrohydrolase that breaks down explosives and confers resistance to an antituberculosis drug:
www.nature.com/articles/s42...
www.nature.com/articles/s42...
The Nankeen Night Heron - basically a real life Pokémon. Made from real heron parts - neck not included.
Round burb.
Round burb.
December 6, 2024 at 3:18 AM
The Nankeen Night Heron - basically a real life Pokémon. Made from real heron parts - neck not included.
Round burb.
Round burb.
Reposted by Colin Scott
2x professorships available in Manchester Institute of Biotechnology including in Microbial Engineering area (broadly defined to include microbiomes, environmental biotech etc) — join us!
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...
Chair Appointments within Manchester Institute of Biotechnology:Manchester Institute of Biotechnology
www.jobs.manchester.ac.uk
November 29, 2024 at 10:01 AM
2x professorships available in Manchester Institute of Biotechnology including in Microbial Engineering area (broadly defined to include microbiomes, environmental biotech etc) — join us!
www.jobs.manchester.ac.uk/Job/JobDetai...
www.jobs.manchester.ac.uk/Job/JobDetai...
Ready for the #CoESynBio meeting, starting later today In Wollongong.
Very happy that Miao Hu (a PDF Fellow in my lab) will be talking about her work with PFAS and fluoride biosensing.
Very happy that Miao Hu (a PDF Fellow in my lab) will be talking about her work with PFAS and fluoride biosensing.
December 2, 2024 at 10:50 PM
Ready for the #CoESynBio meeting, starting later today In Wollongong.
Very happy that Miao Hu (a PDF Fellow in my lab) will be talking about her work with PFAS and fluoride biosensing.
Very happy that Miao Hu (a PDF Fellow in my lab) will be talking about her work with PFAS and fluoride biosensing.
This is incredible
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Continuous evolution of user-defined genes at 1 million times the genomic mutation rate
When nature evolves a gene over eons at scale, it produces a diversity of homologous sequences with patterns of conservation and change that contain rich structural, functional, and historical informa...
www.science.org
November 26, 2024 at 4:33 AM
This is incredible
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
The very talented CSIRO/Murdoch Bioplastics Innovation Hub students showing some very senior government folk their lab and explaining their projects on compostable, bio based plastics
November 21, 2024 at 10:02 AM
The very talented CSIRO/Murdoch Bioplastics Innovation Hub students showing some very senior government folk their lab and explaining their projects on compostable, bio based plastics
For all those #pseudomonas fans - here’s a new review from Hussain Atallas of the CSIRO/Murdoch Bioplastics Innovation Hub, covering the use of Pseudomonas as a plant growth promoting genus
doi.org/10.3389/fmic...
doi.org/10.3389/fmic...
Frontiers | Harnessing Pseudomonas spp. for sustainable plant crop protection
doi.org
November 21, 2024 at 9:43 AM
For all those #pseudomonas fans - here’s a new review from Hussain Atallas of the CSIRO/Murdoch Bioplastics Innovation Hub, covering the use of Pseudomonas as a plant growth promoting genus
doi.org/10.3389/fmic...
doi.org/10.3389/fmic...
Boola Katitjin on the Murdoch University campus- an award winning timber building that incorporates sustainable building practices with the needs of modern teaching and learning. The largest timber building in the Southern Hemisphere and worth a visit if you’re in Perth
November 20, 2024 at 4:54 AM
Boola Katitjin on the Murdoch University campus- an award winning timber building that incorporates sustainable building practices with the needs of modern teaching and learning. The largest timber building in the Southern Hemisphere and worth a visit if you’re in Perth
Reposted by Colin Scott
This is beautiful, it's an ultrafast sequence search that returns genomic context, here's an example I just looked at:
November 19, 2024 at 5:48 PM
This is beautiful, it's an ultrafast sequence search that returns genomic context, here's an example I just looked at:
Reposted by Colin Scott
We are delighted that some of our projects are featured in the BBSRC's new 'Engineering Biology Showcase', which looks at "the impact of how over £800m invested is helping to tackle global challenges with scalable solutions".
www.discover.ukri.org/engineering-...
www.discover.ukri.org/engineering-...
Engineering Biology
Showcasing the power and potential of this transformative technology
www.discover.ukri.org
November 19, 2024 at 4:00 PM
We are delighted that some of our projects are featured in the BBSRC's new 'Engineering Biology Showcase', which looks at "the impact of how over £800m invested is helping to tackle global challenges with scalable solutions".
www.discover.ukri.org/engineering-...
www.discover.ukri.org/engineering-...