Organic Chemistry Portal
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The Organic Chemistry Portal - For daily updates please visit https://www.organic-chemistry.org/abstracts/ and check out https://www.organic-chemistry.org/info/linking/
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Two catalysts were found to be effective in peracid oxidations of alcohols: TEMPO with Bu4NBr or TMP-HBr.
Two catalysts were found to be effective in peracid oxidations of alcohols: TEMPO with Bu4NBr or TMP-HBr.
December 1, 2025 at 12:43 PM
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Two catalysts were found to be effective in peracid oxidations of alcohols: TEMPO with Bu4NBr or TMP-HBr.
Two catalysts were found to be effective in peracid oxidations of alcohols: TEMPO with Bu4NBr or TMP-HBr.
www.organic-chemistry.org/abstracts/li...
A C2-symmetric borinic acid can achieve highly enantioselective desymmetrization of 2,2-disubstituted-1,3-propanediols
A C2-symmetric borinic acid can achieve highly enantioselective desymmetrization of 2,2-disubstituted-1,3-propanediols
December 1, 2025 at 12:40 PM
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A C2-symmetric borinic acid can achieve highly enantioselective desymmetrization of 2,2-disubstituted-1,3-propanediols
A C2-symmetric borinic acid can achieve highly enantioselective desymmetrization of 2,2-disubstituted-1,3-propanediols
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Planar chiral [2.2]paracyclophane-based isothiourea catalysts catalyze a highly efficient enantioselective fluorination of carboxylic acids
Planar chiral [2.2]paracyclophane-based isothiourea catalysts catalyze a highly efficient enantioselective fluorination of carboxylic acids
December 1, 2025 at 12:37 PM
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Planar chiral [2.2]paracyclophane-based isothiourea catalysts catalyze a highly efficient enantioselective fluorination of carboxylic acids
Planar chiral [2.2]paracyclophane-based isothiourea catalysts catalyze a highly efficient enantioselective fluorination of carboxylic acids
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Superacid-catalyzed Pictet-Spengler reactions
Superacid-catalyzed Pictet-Spengler reactions
December 1, 2025 at 12:35 PM
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Superacid-catalyzed Pictet-Spengler reactions
Superacid-catalyzed Pictet-Spengler reactions
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Pd-catalyzed alkene carboamination and carboalkoxylation reactions of a wide range of (hetero)arylthianthrenium triflates
Pd-catalyzed alkene carboamination and carboalkoxylation reactions of a wide range of (hetero)arylthianthrenium triflates
December 1, 2025 at 12:33 PM
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Pd-catalyzed alkene carboamination and carboalkoxylation reactions of a wide range of (hetero)arylthianthrenium triflates
Pd-catalyzed alkene carboamination and carboalkoxylation reactions of a wide range of (hetero)arylthianthrenium triflates
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A three-component reaction of β-ketonitriles, carbonyl- and semistabilized pyridinium ylide precursors, and aldehydes provides trans-4,5-dihydrofuran-3-carbonitriles
A three-component reaction of β-ketonitriles, carbonyl- and semistabilized pyridinium ylide precursors, and aldehydes provides trans-4,5-dihydrofuran-3-carbonitriles
December 1, 2025 at 12:30 PM
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A three-component reaction of β-ketonitriles, carbonyl- and semistabilized pyridinium ylide precursors, and aldehydes provides trans-4,5-dihydrofuran-3-carbonitriles
A three-component reaction of β-ketonitriles, carbonyl- and semistabilized pyridinium ylide precursors, and aldehydes provides trans-4,5-dihydrofuran-3-carbonitriles
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Douglass features The Zhang/Yang Synthesis of Janthinoid A: Zhong-Chao Zhang and Zhen Yang of Peking University Shenzhen Graduate School assembled 3 by way of the oxidative cyclization of the diester 1 to the lactone 2.
Douglass features The Zhang/Yang Synthesis of Janthinoid A: Zhong-Chao Zhang and Zhen Yang of Peking University Shenzhen Graduate School assembled 3 by way of the oxidative cyclization of the diester 1 to the lactone 2.
November 30, 2025 at 5:04 PM
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Douglass features The Zhang/Yang Synthesis of Janthinoid A: Zhong-Chao Zhang and Zhen Yang of Peking University Shenzhen Graduate School assembled 3 by way of the oxidative cyclization of the diester 1 to the lactone 2.
Douglass features The Zhang/Yang Synthesis of Janthinoid A: Zhong-Chao Zhang and Zhen Yang of Peking University Shenzhen Graduate School assembled 3 by way of the oxidative cyclization of the diester 1 to the lactone 2.
Molecule of the week: Janthinoid A
Janthinoid A, isolated from the tabacum-derived endophytic fungus Penicillium janthinellum TE-43, showed in vivo anti-tumor activity against NSCLC cells A549.
More Info: www.organic-chemistry.org/Highlights/2...
Janthinoid A, isolated from the tabacum-derived endophytic fungus Penicillium janthinellum TE-43, showed in vivo anti-tumor activity against NSCLC cells A549.
More Info: www.organic-chemistry.org/Highlights/2...
November 30, 2025 at 5:01 PM
Molecule of the week: Janthinoid A
Janthinoid A, isolated from the tabacum-derived endophytic fungus Penicillium janthinellum TE-43, showed in vivo anti-tumor activity against NSCLC cells A549.
More Info: www.organic-chemistry.org/Highlights/2...
Janthinoid A, isolated from the tabacum-derived endophytic fungus Penicillium janthinellum TE-43, showed in vivo anti-tumor activity against NSCLC cells A549.
More Info: www.organic-chemistry.org/Highlights/2...
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tert-Butanesulfinyl imines can be used for asymmetric syntheses of β-substituted as well as β,β- and α,β-disubstituted β-amino acids
tert-Butanesulfinyl imines can be used for asymmetric syntheses of β-substituted as well as β,β- and α,β-disubstituted β-amino acids
November 28, 2025 at 12:55 PM
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tert-Butanesulfinyl imines can be used for asymmetric syntheses of β-substituted as well as β,β- and α,β-disubstituted β-amino acids
tert-Butanesulfinyl imines can be used for asymmetric syntheses of β-substituted as well as β,β- and α,β-disubstituted β-amino acids
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The combination of Ph3P/ICH2CH2I promotes a dehydroxylative sulfonylation of benzylic and allylic alcohols with a variety of sulfinates
The combination of Ph3P/ICH2CH2I promotes a dehydroxylative sulfonylation of benzylic and allylic alcohols with a variety of sulfinates
November 28, 2025 at 12:51 PM
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The combination of Ph3P/ICH2CH2I promotes a dehydroxylative sulfonylation of benzylic and allylic alcohols with a variety of sulfinates
The combination of Ph3P/ICH2CH2I promotes a dehydroxylative sulfonylation of benzylic and allylic alcohols with a variety of sulfinates
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A formal (3+2)-cycloaddition of donor-acceptor cyclopropanes and ammonium thiocyanate
A formal (3+2)-cycloaddition of donor-acceptor cyclopropanes and ammonium thiocyanate
November 28, 2025 at 12:46 PM
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A formal (3+2)-cycloaddition of donor-acceptor cyclopropanes and ammonium thiocyanate
A formal (3+2)-cycloaddition of donor-acceptor cyclopropanes and ammonium thiocyanate
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A useful catalyst system for the Heck coupling of aryl chlorides has been developed. The choice of ligand is critical for activity.
A useful catalyst system for the Heck coupling of aryl chlorides has been developed. The choice of ligand is critical for activity.
November 28, 2025 at 12:42 PM
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A useful catalyst system for the Heck coupling of aryl chlorides has been developed. The choice of ligand is critical for activity.
A useful catalyst system for the Heck coupling of aryl chlorides has been developed. The choice of ligand is critical for activity.
www.organic-chemistry.org/abstracts/li...
A catalyst-free synthesis of phosphinic amides from hydroxyl amines and chlorophosphines
A catalyst-free synthesis of phosphinic amides from hydroxyl amines and chlorophosphines
November 28, 2025 at 12:37 PM
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A catalyst-free synthesis of phosphinic amides from hydroxyl amines and chlorophosphines
A catalyst-free synthesis of phosphinic amides from hydroxyl amines and chlorophosphines
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N-Benzyl ketimines undergo [3 + 2] cycloaddition with arylacetylenes in KOtBu/DMSO solution to provide 2,3,5-triarylpyrrolines
N-Benzyl ketimines undergo [3 + 2] cycloaddition with arylacetylenes in KOtBu/DMSO solution to provide 2,3,5-triarylpyrrolines
November 28, 2025 at 12:32 PM
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N-Benzyl ketimines undergo [3 + 2] cycloaddition with arylacetylenes in KOtBu/DMSO solution to provide 2,3,5-triarylpyrrolines
N-Benzyl ketimines undergo [3 + 2] cycloaddition with arylacetylenes in KOtBu/DMSO solution to provide 2,3,5-triarylpyrrolines
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Aldimines undergo nucleophilic addition with diethyl phosphite in the presence of a catalytic amount of zirconium tetrachloride
Aldimines undergo nucleophilic addition with diethyl phosphite in the presence of a catalytic amount of zirconium tetrachloride
November 28, 2025 at 12:29 PM
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Aldimines undergo nucleophilic addition with diethyl phosphite in the presence of a catalytic amount of zirconium tetrachloride
Aldimines undergo nucleophilic addition with diethyl phosphite in the presence of a catalytic amount of zirconium tetrachloride
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Boronic acid catalyzed one-pot reductions of quinolines with Hantzsch ester followed by N-arylations via external base-free Chan-Evans-Lam coupling
Boronic acid catalyzed one-pot reductions of quinolines with Hantzsch ester followed by N-arylations via external base-free Chan-Evans-Lam coupling
November 28, 2025 at 12:26 PM
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Boronic acid catalyzed one-pot reductions of quinolines with Hantzsch ester followed by N-arylations via external base-free Chan-Evans-Lam coupling
Boronic acid catalyzed one-pot reductions of quinolines with Hantzsch ester followed by N-arylations via external base-free Chan-Evans-Lam coupling
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Chiral bis(oxazoline)alkynylphosphine ligands can be used in Rh-catalyzed highly regio- and enantioselective allylic amination reactions
Chiral bis(oxazoline)alkynylphosphine ligands can be used in Rh-catalyzed highly regio- and enantioselective allylic amination reactions
November 28, 2025 at 12:24 PM
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Chiral bis(oxazoline)alkynylphosphine ligands can be used in Rh-catalyzed highly regio- and enantioselective allylic amination reactions
Chiral bis(oxazoline)alkynylphosphine ligands can be used in Rh-catalyzed highly regio- and enantioselective allylic amination reactions
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Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3
Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3
November 27, 2025 at 11:02 AM
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Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3
Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3
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Eosin Y catalyzes an efficient photochemical aerobic oxidation of various benzyl alcohols to the corresponding aldehydes or ketones
Eosin Y catalyzes an efficient photochemical aerobic oxidation of various benzyl alcohols to the corresponding aldehydes or ketones
November 27, 2025 at 10:59 AM
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Eosin Y catalyzes an efficient photochemical aerobic oxidation of various benzyl alcohols to the corresponding aldehydes or ketones
Eosin Y catalyzes an efficient photochemical aerobic oxidation of various benzyl alcohols to the corresponding aldehydes or ketones
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A visible light-promoted divergent cycloaddition of α-diazo esters to hexahydro-1,3,5-triazines provides a series of aziridines and imidazolidines
A visible light-promoted divergent cycloaddition of α-diazo esters to hexahydro-1,3,5-triazines provides a series of aziridines and imidazolidines
November 27, 2025 at 10:56 AM
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A visible light-promoted divergent cycloaddition of α-diazo esters to hexahydro-1,3,5-triazines provides a series of aziridines and imidazolidines
A visible light-promoted divergent cycloaddition of α-diazo esters to hexahydro-1,3,5-triazines provides a series of aziridines and imidazolidines
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A practical method for large-scale acetylation of 1° and 2° alcohols as well as diols has been developed.
A practical method for large-scale acetylation of 1° and 2° alcohols as well as diols has been developed.
November 27, 2025 at 10:53 AM
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A practical method for large-scale acetylation of 1° and 2° alcohols as well as diols has been developed.
A practical method for large-scale acetylation of 1° and 2° alcohols as well as diols has been developed.
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A Pd-catalyzed enantioselective aminochlorination of alkenes provides diverse 3-chloropiperidines via a 6-endo cyclization
A Pd-catalyzed enantioselective aminochlorination of alkenes provides diverse 3-chloropiperidines via a 6-endo cyclization
November 27, 2025 at 10:51 AM
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A Pd-catalyzed enantioselective aminochlorination of alkenes provides diverse 3-chloropiperidines via a 6-endo cyclization
A Pd-catalyzed enantioselective aminochlorination of alkenes provides diverse 3-chloropiperidines via a 6-endo cyclization
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A solvent-free, TfOH-promoted decyanative cyclization enables the synthesis of 2,1-benzisoxazoles in good yields.
A solvent-free, TfOH-promoted decyanative cyclization enables the synthesis of 2,1-benzisoxazoles in good yields.
November 27, 2025 at 10:48 AM
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A solvent-free, TfOH-promoted decyanative cyclization enables the synthesis of 2,1-benzisoxazoles in good yields.
A solvent-free, TfOH-promoted decyanative cyclization enables the synthesis of 2,1-benzisoxazoles in good yields.
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November 26, 2025 at 1:36 PM
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www.organic-chemistry.org/info/present...
30+ years of synthetic expertise, now delivering building blocks & personalized insights through custom synthesis
www.organic-chemistry.org/info/present...
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www.organic-chemistry.org/abstracts/li...
A polystyrene-bound pyridineboronic acid was synthesized and shown to be an efficient, easily recoverable and reusable amidation catalyst.
A polystyrene-bound pyridineboronic acid was synthesized and shown to be an efficient, easily recoverable and reusable amidation catalyst.
November 26, 2025 at 1:19 PM
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A polystyrene-bound pyridineboronic acid was synthesized and shown to be an efficient, easily recoverable and reusable amidation catalyst.
A polystyrene-bound pyridineboronic acid was synthesized and shown to be an efficient, easily recoverable and reusable amidation catalyst.