@ophirklein.bsky.social
CNPY4 joins the growing list of lipid-binding regulators keeping cellular membranes balanced — exciting times for membrane & lipid biology!
#lipidbiology #cellbiology #biorxiv #sphingolipids
#lipidbiology #cellbiology #biorxiv #sphingolipids
October 18, 2025 at 6:10 PM
CNPY4 joins the growing list of lipid-binding regulators keeping cellular membranes balanced — exciting times for membrane & lipid biology!
#lipidbiology #cellbiology #biorxiv #sphingolipids
#lipidbiology #cellbiology #biorxiv #sphingolipids
Why it matters 🧠
🧩 Reveals a new lipid-binding regulator in cells
⚙️ Links SAPLIP family proteins to membrane lipid regulation
🧪 Opens questions: how is CNPY4 controlled? disease relevance?
🧩 Reveals a new lipid-binding regulator in cells
⚙️ Links SAPLIP family proteins to membrane lipid regulation
🧪 Opens questions: how is CNPY4 controlled? disease relevance?
October 18, 2025 at 6:10 PM
Why it matters 🧠
🧩 Reveals a new lipid-binding regulator in cells
⚙️ Links SAPLIP family proteins to membrane lipid regulation
🧪 Opens questions: how is CNPY4 controlled? disease relevance?
🧩 Reveals a new lipid-binding regulator in cells
⚙️ Links SAPLIP family proteins to membrane lipid regulation
🧪 Opens questions: how is CNPY4 controlled? disease relevance?
Our work uncovers a new molecular player: CNPY4.
CNPY4, a saposin-like protein, directly binds sphingolipids
Loss or perturbation of CNPY4 disrupts lipid distribution + abundance → reshaping membrane architecture & possibly signaling pathways. This is a new layer of control in lipid homeostasis.
CNPY4, a saposin-like protein, directly binds sphingolipids
Loss or perturbation of CNPY4 disrupts lipid distribution + abundance → reshaping membrane architecture & possibly signaling pathways. This is a new layer of control in lipid homeostasis.
October 18, 2025 at 6:10 PM
Our work uncovers a new molecular player: CNPY4.
CNPY4, a saposin-like protein, directly binds sphingolipids
Loss or perturbation of CNPY4 disrupts lipid distribution + abundance → reshaping membrane architecture & possibly signaling pathways. This is a new layer of control in lipid homeostasis.
CNPY4, a saposin-like protein, directly binds sphingolipids
Loss or perturbation of CNPY4 disrupts lipid distribution + abundance → reshaping membrane architecture & possibly signaling pathways. This is a new layer of control in lipid homeostasis.
The findings, if confirmed in humans, could one day lead to treatments that enable rapid, scarless recovery from skin wounds on other parts of the body."
www.cedars-sinai.org/newsroom/pre...
www.cedars-sinai.org/newsroom/pre...
Preclinical Study Unlocks a Mystery of Rapid Mouth Healing
Your mouth is a magician. Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University ...
www.cedars-sinai.org
July 4, 2025 at 7:27 AM
The findings, if confirmed in humans, could one day lead to treatments that enable rapid, scarless recovery from skin wounds on other parts of the body."
www.cedars-sinai.org/newsroom/pre...
www.cedars-sinai.org/newsroom/pre...
"Your mouth is a magician. Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A new study has discovered one secret of this disappearing act.
Preclinical Study Unlocks a Mystery of Rapid Mouth Healing
Your mouth is a magician. Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University ...
www.cedars-sinai.org
July 4, 2025 at 7:27 AM
"Your mouth is a magician. Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A new study has discovered one secret of this disappearing act.
Sorry to read this and glad you are on the mend!
June 3, 2025 at 11:23 PM
Sorry to read this and glad you are on the mend!