Jieran Sun
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onesinglecell.bsky.social
Jieran Sun
@onesinglecell.bsky.social
I treat every #singleCell gently. | PhD in Comp Bio at CHUV, Lausanne #OpenScience #SpatialTranscriptomics
Reposted by Jieran Sun
Excited to share our preprint on selecting validation metrics for single-cell and spatial omics! Explore how to evaluate embeddings, graphs, clustering, and spatial domains with biological relevance in mind. Plus, discover poem, our R package with new spatially-aware metrics!
doi.org/10.1101/2024...
On metrics for subpopulation detection in single-cell and spatial omics data
Benchmarks are crucial to understanding the strengths and weaknesses of the growing number of tools for single-cell and spatial omics analysis. A key task is to distinguish subpopulations within compl...
doi.org
December 5, 2024 at 8:03 AM
Reposted by Jieran Sun
Super excited to share our Human Neural Organoid Atlas, now out in Nature! Led by @zhisonghe.bsky.social @josch1.bsky.social, and myself, this resource was created from 36 scRNA-seq datasets—totalling over 1.7 million cells! 🔬✨
 www.nature.com/articles/s41...

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An integrated transcriptomic cell atlas of human neural organoids - Nature
A human neural organoid cell atlas integrating 36 single-cell transcriptomic datasets shows cell types and states and estimates transcriptomic similarity between primary and organoid counterparts, sho...
www.nature.com
November 21, 2024 at 10:11 AM
Reposted by Jieran Sun
Sometimes you just have to persevere through negative reviews. Reviewers, please be kind :) #methodsmatter bit.ly/gs2-scholar
November 25, 2024 at 3:05 AM