Oscar
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omt2007.bsky.social
Oscar
@omt2007.bsky.social
61 followers 140 following 5 posts
Scientist, son, husband, father, friend, runner and entrepreneur. Fighting sarcoma from the lab since 2001.
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Reposted by Oscar
irbbarcelona.org
Just kicked off the #BarcelonaBioMed Conference “When Development Meets #Cancer-Origins, Models & Therapies in #ChildhoodCancer”

Excited to hear from an outstanding line-up of speakers!

Organized by #IRBBarcelona & @sjdhospitalbarcelona.org

With the support of Fundación @bbvaenespana.bsky.social
November 10, 2025 at 8:34 AM
omt2007.bsky.social
Indeed!
grunewaldlab.bsky.social Grünewald Lab @grunewaldlab.bsky.social · Aug 11
The new findings of Alina Ritter showcase that this approach may be especially feasible for metastatic disease since an impirtant viral docking site is highly expressed in metastatic lesions and even contributes to metastasis in #Ewing #sarcoma.

We will not stop until there is a cure!
August 19, 2025 at 2:03 PM
Reposted by Oscar
grunewaldlab.bsky.social
Very proud on our stellar Alina Ritter for her frist first-author paper:

Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances #chemotherapy efficacy in #Ewing #sarcoma

tinyurl.com/3kcs3bc9

@dkfz.bsky.social
@uniheidelberg.bsky.social
@nct-heidelberg.bsky.social
August 11, 2025 at 6:38 AM
Reposted by Oscar
sandradcastillo.bsky.social
We’re happy 😄 to share our latest work in Cancer Discov @theaacr.bsky.social – we discover that PTEN UPD 🧬 in endothelial cells causes vascular malformations in PTEN Hamartoma Tumor Syndrome (PHTS), create a new mouse model 🐀 & test PI3K signaling inhibitors 💊.

aacrjournals.org/cancerdiscov...
Somatic uniparental disomy of PTEN in endothelial cells causes vascular malformations in patients with PTEN Hamartoma Tumor Syndrome
Abstract. PTEN Hamartoma Tumor Syndrome (PHTS) is a rare tumor risk disorder caused by germline loss-of-function mutations in PTEN. Half of these patients develop vascular malformations, a hamartoma c...
aacrjournals.org
March 29, 2025 at 12:12 PM
Reposted by Oscar
grunewaldlab.bsky.social
Targeting replication stress in neuroblastoma by exploiting the synergistic potential of second generation RRM2 and CHK1 inhibitors

www.biorxiv.org/content/10.1...
Targeting replication stress in neuroblastoma by exploiting the synergistic potential of second generation RRM2 and CHK1 inhibitors
Tumor cells often cope with elevated levels of replication stress (RS) causing increased dependency on ATR-CHK1 signalling. We previously presented RRM2, the regulatory component of the ribonucleotide...
www.biorxiv.org
March 3, 2025 at 11:07 AM
omt2007.bsky.social
idibell.cat/en/2025/01/n...
New investment in the research against Ewing’s sarcoma – IDIBELL
idibell.cat
January 30, 2025 at 6:46 AM
Reposted by Oscar
albertvilella.bsky.social
In #biotech #stocks news, Donald Trump’s return to the White House is already having a big impact at the $47.4 billion U.S. National Institutes of Health (NIH), with the new administration imposing a wide range of restrictions, including the abrupt cancellation of grant review panels.
January 23, 2025 at 3:30 PM
omt2007.bsky.social
doi.org/10.1002/1878... Happy to share our last work! Great effort by @marionachicon.bsky.social and great collaborations! #ewingsarcoma #metastasis #animalmodels #research
FEBS Press
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biolo....
doi.org
January 6, 2025 at 10:53 AM
omt2007.bsky.social
December is always a good month! We have new doctor in da house! #sarcoma #research Sara Sánchez-Serra 👏🏻👏🏻👏🏻 Very proud of her!
December 16, 2024 at 3:28 PM
omt2007.bsky.social
I'm really happy to post for the first time here the words written in an incoming e-mail I just got: Dear Dr. Martinez Tirado:
We are delighted to inform you that your manuscript....😃
#sarcoma #metastasis #mousemodel
November 14, 2024 at 11:07 AM