Oscar Marcelo Lazo
@omlazo.science
Broad-spectrum neurobiologist, cancionista, & escribidor de brocha gorda. Dad of three humans, married to their unfathomable mum. I ask questions to neurons and brains at the UCL Queen Square Institute of Neurology 🇬🇧 and Universidad San Sebastián 🇨🇱.
The end of an era for experimental psychology and emotions research. Hopefully his legacy and intellectual influence will keep his work alive far beyond today.
November 19, 2025 at 3:20 PM
The end of an era for experimental psychology and emotions research. Hopefully his legacy and intellectual influence will keep his work alive far beyond today.
Este viernes 21 desde las 9.30 am en FACSO, @uchile.bsky.social. Estaré hablando de organización y autonomía biológica, en el contexto de la cognición humana.
November 19, 2025 at 4:48 AM
Este viernes 21 desde las 9.30 am en FACSO, @uchile.bsky.social. Estaré hablando de organización y autonomía biológica, en el contexto de la cognición humana.
This may be an unpopular thing to say today, but Venezuela deserved a much better political opposition — and now it’s harder than ever for them to get one.
October 10, 2025 at 8:00 PM
This may be an unpopular thing to say today, but Venezuela deserved a much better political opposition — and now it’s harder than ever for them to get one.
Reposted by Oscar Marcelo Lazo
Annual Scientific Meeting of the British Neuropathological Society, 28–30 Jan 2026 at The View, Royal College of Surgeons of England, London.
www.dementiaresearcher.nihr.ac.uk/event/127th-...
www.dementiaresearcher.nihr.ac.uk/event/127th-...
127th British Neuropathological Society meeting
Annual Scientific Meeting of the British Neuropathological Society, 28–30 Jan 2026 at The View, Royal College of Surgeons of England, London.
www.dementiaresearcher.nihr.ac.uk
October 9, 2025 at 12:06 PM
Annual Scientific Meeting of the British Neuropathological Society, 28–30 Jan 2026 at The View, Royal College of Surgeons of England, London.
www.dementiaresearcher.nihr.ac.uk/event/127th-...
www.dementiaresearcher.nihr.ac.uk/event/127th-...
La democracia liberal patas pa arriba: un comercio no puede ponerle a sus clientes una regla de convivencia básica, como no portar armas visiblemente en el interior del súper, porque viola sus derechos constitucionales. ¡Jolín!
Floridians will be able to openly carry firearms while shopping at Publix, the largest supermarket chain in the state, the company said on Thursday. The announcement came after a state appeals court ruled that a Florida ban on people openly carrying firearms was unconstitutional.
Customers May Openly Carry Firearms in Florida’s Publix Stores, Company Says
The supermarket chain said it was complying with state law, including a ruling last month that overturned a ban on openly carrying firearms.
nyti.ms
October 9, 2025 at 10:00 PM
La democracia liberal patas pa arriba: un comercio no puede ponerle a sus clientes una regla de convivencia básica, como no portar armas visiblemente en el interior del súper, porque viola sus derechos constitucionales. ¡Jolín!
Reposted by Oscar Marcelo Lazo
Excited to share our latest manuscript by @saikat2025.bsky.social and an international team, reporting variants in the EARP- and GARP-interacting protein EIPR1 associated with a neurodevelopmental disorder. Will send you the PDF if you can’t access the article: academic.oup.com/brain/articl...
EIPR1 variants cause a neurodevelopmental disorder with endolysosomal and dense core vesicle defects
Abstract. EIPR1 (EARP-interacting protein 1, formerly known as TSSC1) is a WD40-domain protein that interacts with the EARP (endosome-associated recycling
academic.oup.com
October 8, 2025 at 3:33 PM
Excited to share our latest manuscript by @saikat2025.bsky.social and an international team, reporting variants in the EARP- and GARP-interacting protein EIPR1 associated with a neurodevelopmental disorder. Will send you the PDF if you can’t access the article: academic.oup.com/brain/articl...
Latinoamérica en El Tiny! youtu.be/UEqTIwRrWvA?...
31 Minutos: Tiny Desk Concert
YouTube video by NPR Music
youtu.be
October 6, 2025 at 9:59 PM
Latinoamérica en El Tiny! youtu.be/UEqTIwRrWvA?...
Join us today for a new session of our Journal Club on Psychology & Neuroscience —we are having a special guest, @tonchimatta.bsky.social, who comes to discuss her favourite bit of neuroscience: brain-machine interfaces and their potential.
September 30, 2025 at 11:21 AM
Join us today for a new session of our Journal Club on Psychology & Neuroscience —we are having a special guest, @tonchimatta.bsky.social, who comes to discuss her favourite bit of neuroscience: brain-machine interfaces and their potential.
Reposted by Oscar Marcelo Lazo
#ScienceUnderSiege: How to Fight the Five Most Powerful Forces that Threaten Our World
by @peterhotezmdphd.bsky.social & yours truly,
comes out one week from today! 🙂
Preorder now:
Barnes & Noble: www.barnesandnoble.com/w/science-un...
Publisher: www.hachettebookgroup.com/titles/micha...
by @peterhotezmdphd.bsky.social & yours truly,
comes out one week from today! 🙂
Preorder now:
Barnes & Noble: www.barnesandnoble.com/w/science-un...
Publisher: www.hachettebookgroup.com/titles/micha...
September 2, 2025 at 12:18 PM
#ScienceUnderSiege: How to Fight the Five Most Powerful Forces that Threaten Our World
by @peterhotezmdphd.bsky.social & yours truly,
comes out one week from today! 🙂
Preorder now:
Barnes & Noble: www.barnesandnoble.com/w/science-un...
Publisher: www.hachettebookgroup.com/titles/micha...
by @peterhotezmdphd.bsky.social & yours truly,
comes out one week from today! 🙂
Preorder now:
Barnes & Noble: www.barnesandnoble.com/w/science-un...
Publisher: www.hachettebookgroup.com/titles/micha...
Reposted by Oscar Marcelo Lazo
Atención chilenos, estamos haciendo un estudio narrativo de emociones evocadas por los candidatos a la presidencia. Ayer estuvimos presentándolo en @meganoticiascl.bsky.social y sigue abierto para que todos puedan evaluar a un candidato al azar.
Lo ves aquí: pro.amorporlamarca.com/direct-surve...
Lo ves aquí: pro.amorporlamarca.com/direct-surve...
August 13, 2025 at 9:12 PM
Atención chilenos, estamos haciendo un estudio narrativo de emociones evocadas por los candidatos a la presidencia. Ayer estuvimos presentándolo en @meganoticiascl.bsky.social y sigue abierto para que todos puedan evaluar a un candidato al azar.
Lo ves aquí: pro.amorporlamarca.com/direct-surve...
Lo ves aquí: pro.amorporlamarca.com/direct-surve...
Atención chilenos, estamos haciendo un estudio narrativo de emociones evocadas por los candidatos a la presidencia. Ayer estuvimos presentándolo en @meganoticiascl.bsky.social y sigue abierto para que todos puedan evaluar a un candidato al azar.
Lo ves aquí: pro.amorporlamarca.com/direct-surve...
Lo ves aquí: pro.amorporlamarca.com/direct-surve...
August 13, 2025 at 9:12 PM
Atención chilenos, estamos haciendo un estudio narrativo de emociones evocadas por los candidatos a la presidencia. Ayer estuvimos presentándolo en @meganoticiascl.bsky.social y sigue abierto para que todos puedan evaluar a un candidato al azar.
Lo ves aquí: pro.amorporlamarca.com/direct-surve...
Lo ves aquí: pro.amorporlamarca.com/direct-surve...
Reposted by Oscar Marcelo Lazo
Editorial | "Las imágenes y los relatos del horror de Hiroshima y Nagasaki no son una conmemoración histórica más: sirven como recuerdo constante del daño existencial que la humanidad puede infligirse a sí misma"
La presencia de Hiroshima | Editorial
El 80 aniversario de la destrucción de la ciudad japonesa advierte contra la actual frivolidad global sobre la amenaza nuclear
elpais.com
August 6, 2025 at 8:23 AM
Editorial | "Las imágenes y los relatos del horror de Hiroshima y Nagasaki no son una conmemoración histórica más: sirven como recuerdo constante del daño existencial que la humanidad puede infligirse a sí misma"
Random chat last night...
— Dad, I'm not vaccinating. They say the HPV vaccine is the most painful one!
— Do you know what a papilloma is?
— No...
— A cause of cancer
— x___x
— A type of cancer that use to cause a lot of trouble and now you can avoid just getting vaccinated.
— Ok
— Dad, I'm not vaccinating. They say the HPV vaccine is the most painful one!
— Do you know what a papilloma is?
— No...
— A cause of cancer
— x___x
— A type of cancer that use to cause a lot of trouble and now you can avoid just getting vaccinated.
— Ok
August 5, 2025 at 2:06 PM
Random chat last night...
— Dad, I'm not vaccinating. They say the HPV vaccine is the most painful one!
— Do you know what a papilloma is?
— No...
— A cause of cancer
— x___x
— A type of cancer that use to cause a lot of trouble and now you can avoid just getting vaccinated.
— Ok
— Dad, I'm not vaccinating. They say the HPV vaccine is the most painful one!
— Do you know what a papilloma is?
— No...
— A cause of cancer
— x___x
— A type of cancer that use to cause a lot of trouble and now you can avoid just getting vaccinated.
— Ok
Tengo que hacer algunas clases este semestre. Afortunadamente son algunas de las cosas que más me entusiasman en el mundo, así que simplemente espero poder transferir algo de ese mismo entusiasmo.
¡Se viene el segundo semestre!
¡Se viene el segundo semestre!
August 1, 2025 at 3:17 PM
Tengo que hacer algunas clases este semestre. Afortunadamente son algunas de las cosas que más me entusiasman en el mundo, así que simplemente espero poder transferir algo de ese mismo entusiasmo.
¡Se viene el segundo semestre!
¡Se viene el segundo semestre!
I've been culturing intact explants of embryonic mouse basal forebrain. It's a pretty cool way to model interactions between the different BFN populations in vitro, both in physiology and disease, specially in Alzheimer's where these neurons are particularly vulnerable.
[Confocal— DAPI+Phalloidin]
[Confocal— DAPI+Phalloidin]
July 31, 2025 at 4:03 PM
I've been culturing intact explants of embryonic mouse basal forebrain. It's a pretty cool way to model interactions between the different BFN populations in vitro, both in physiology and disease, specially in Alzheimer's where these neurons are particularly vulnerable.
[Confocal— DAPI+Phalloidin]
[Confocal— DAPI+Phalloidin]
This Thursday 31st/July at 3.30 pm we have another session of our Journal Club on Psychology and Neuroscience. This month we are led by Prof. @pauladagnino.bsky.social to discuss mental health outcomes monitoring in the public system.
Join us!
Join us!
July 28, 2025 at 3:29 PM
This Thursday 31st/July at 3.30 pm we have another session of our Journal Club on Psychology and Neuroscience. This month we are led by Prof. @pauladagnino.bsky.social to discuss mental health outcomes monitoring in the public system.
Join us!
Join us!
Reposted by Oscar Marcelo Lazo
Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons https://www.biorxiv.org/content/10.1101/2025.07.15.664857v1
July 19, 2025 at 12:15 AM
Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons https://www.biorxiv.org/content/10.1101/2025.07.15.664857v1
I came across this concept today and I liked this blog post on epistemic respect and peer-review: blogs.lse.ac.uk/impactofsoci...
For Epistemic Respect – Against Reviewer 2 - Impact of Social Sciences
Gorgi Krlev & Andre Spicer draw on an encounter with reviewer 2 and the subsequent twitterstorm, to explain what epistemic respect means and how to uphold it.
blogs.lse.ac.uk
July 8, 2025 at 11:46 PM
I came across this concept today and I liked this blog post on epistemic respect and peer-review: blogs.lse.ac.uk/impactofsoci...
Coming to London on a summer Saturday—when Pride celebrations were in full swing, and everyone was out with friends in all sorts of playful attire—has been absolutely vivifying!
July 5, 2025 at 11:21 PM
Coming to London on a summer Saturday—when Pride celebrations were in full swing, and everyone was out with friends in all sorts of playful attire—has been absolutely vivifying!
I grew up one little bit today.
I'm going back to the lab in London in a couple of weeks, and instead of booking a bed in a noisy backpackers' hostel as usual, I evolved to booking myself a room in a proper family-run hotel next door.
Yeahp... getting old.
I'm going back to the lab in London in a couple of weeks, and instead of booking a bed in a noisy backpackers' hostel as usual, I evolved to booking myself a room in a proper family-run hotel next door.
Yeahp... getting old.
June 23, 2025 at 1:37 PM
I grew up one little bit today.
I'm going back to the lab in London in a couple of weeks, and instead of booking a bed in a noisy backpackers' hostel as usual, I evolved to booking myself a room in a proper family-run hotel next door.
Yeahp... getting old.
I'm going back to the lab in London in a couple of weeks, and instead of booking a bed in a noisy backpackers' hostel as usual, I evolved to booking myself a room in a proper family-run hotel next door.
Yeahp... getting old.
Reposted by Oscar Marcelo Lazo
🙏 to editor Sian Lewis for this @natrevneuro.nature.com highlight on our recent paper
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An intriguing role of repeat-element RNAs in nerve injury repair - Nature Reviews Neuroscience
A polyA-tail-directed RNA sequencing approach that was used to investigate transcriptomic changes in dorsal root ganglia following nerve crush revealed unexpected upregulation of a specific set of B2-...
www.nature.com
June 7, 2025 at 9:44 AM
🙏 to editor Sian Lewis for this @natrevneuro.nature.com highlight on our recent paper
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Oscar Marcelo Lazo
May 27, 2025 at 11:34 AM
True that the promising story about jacifusen still requires more data to weight its impact in the real world, but I can't help thinking about the 16-y.o. kid with ALS that after a year of treatment is breathing again and recovering movement. Unprecedented progress! www.thelancet.com/journals/lan...
Antisense oligonucleotide jacifusen for FUS-ALS: an investigator-initiated, multicentre, open-label case series
The findings suggest the safety and possible efficacy of jacifusen for treating FUS-ALS.
The efficacy of jacifusen is being further evaluated in an ongoing clinical trial.
www.thelancet.com
May 27, 2025 at 2:45 AM
True that the promising story about jacifusen still requires more data to weight its impact in the real world, but I can't help thinking about the 16-y.o. kid with ALS that after a year of treatment is breathing again and recovering movement. Unprecedented progress! www.thelancet.com/journals/lan...
