olafklingbeil.bsky.social
@olafklingbeil.bsky.social
Reposted
So happy to see this live, Slim! Congratulations to you, Ernesto and the whole team for your resilience, vision and creativity!
Thrilled to share my 1st brainchild, out today @naturegenet.bsky.social 🚀 Been hearing a lot about fetal-like states lately? We uncover the molecular mechanisms, functional significance and clinical relevance of #oncofetal reprogramming in CRC. www.nature.com/articles/s41... (rdcu.be/d9iSN) a 🧵
February 10, 2025 at 3:31 PM
Reposted
Exciting paper by Chris Vakoc @cshlaboratory.bsky.social on how to target the YAP/TAZ pathway out in Cancer Discovery! aacrjournals.org/cancerdiscov...
MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer
The kinases MARK2 and MARK3 are identified as requirements for the function of the YAP and TAZ oncogenes, thus providing a druggable vulnerability in Hippo-dysregulated carcinomas and sarcomas.
aacrjournals.org
December 15, 2024 at 9:57 AM