Osteoarthritis and Cartilage Journal
@oacjournal.bsky.social
Osteoarthritis and Cartilage, and Osteoarthritis and Cartilage Open - official journals of OARSI. Impact factor 9.
http://www.oarsijournal.com
http://www.oarsijournal.com
🆕 Editor's Choice!
This month's featured paper is on plasma #lipoprotein and #osteoarthritis risk
Lipoprotein subclasses play diverse roles in health and disease there is so much more to learn about its impact on knee #osteoarthritis
Read more from Li et al - www.oarsijournal.com/article/S106...
This month's featured paper is on plasma #lipoprotein and #osteoarthritis risk
Lipoprotein subclasses play diverse roles in health and disease there is so much more to learn about its impact on knee #osteoarthritis
Read more from Li et al - www.oarsijournal.com/article/S106...
November 14, 2025 at 3:19 PM
🆕 Editor's Choice!
This month's featured paper is on plasma #lipoprotein and #osteoarthritis risk
Lipoprotein subclasses play diverse roles in health and disease there is so much more to learn about its impact on knee #osteoarthritis
Read more from Li et al - www.oarsijournal.com/article/S106...
This month's featured paper is on plasma #lipoprotein and #osteoarthritis risk
Lipoprotein subclasses play diverse roles in health and disease there is so much more to learn about its impact on knee #osteoarthritis
Read more from Li et al - www.oarsijournal.com/article/S106...
How did Zhou et al. monitor the temporal profiling of lipid mediators in the synovium and tibial plateau during joint inflammation🧐? Learn out this work in this month's #EditorsChoice paper for #Basic #Science.
🔗
www.sciencedirect.com/science/arti...
🔗
www.sciencedirect.com/science/arti...
November 10, 2025 at 12:39 PM
How did Zhou et al. monitor the temporal profiling of lipid mediators in the synovium and tibial plateau during joint inflammation🧐? Learn out this work in this month's #EditorsChoice paper for #Basic #Science.
🔗
www.sciencedirect.com/science/arti...
🔗
www.sciencedirect.com/science/arti...
👋 Are you a young researcher interested in editorial roles?
If that is you, OAC is currently seeking Editorial Fellows for 2026!
Fellows will be mentored by our Editors-in-chief David Hunter @jointsintheworld.bsky.social and our team of Deputy Editors.
form.jotform.com/242315596999...
If that is you, OAC is currently seeking Editorial Fellows for 2026!
Fellows will be mentored by our Editors-in-chief David Hunter @jointsintheworld.bsky.social and our team of Deputy Editors.
form.jotform.com/242315596999...
October 31, 2025 at 11:31 PM
👋 Are you a young researcher interested in editorial roles?
If that is you, OAC is currently seeking Editorial Fellows for 2026!
Fellows will be mentored by our Editors-in-chief David Hunter @jointsintheworld.bsky.social and our team of Deputy Editors.
form.jotform.com/242315596999...
If that is you, OAC is currently seeking Editorial Fellows for 2026!
Fellows will be mentored by our Editors-in-chief David Hunter @jointsintheworld.bsky.social and our team of Deputy Editors.
form.jotform.com/242315596999...
#New research highlights the key role of the NGF/TrkA pathway in chronic #OA pain. Through gene expression analysis, specific genes and pathways linked to OA progression were found, offering insights for targeted therapies against OA pain. #PainResearch
📖:
www.sciencedirect.com/science/arti...
📖:
www.sciencedirect.com/science/arti...
October 28, 2025 at 1:19 PM
#New research highlights the key role of the NGF/TrkA pathway in chronic #OA pain. Through gene expression analysis, specific genes and pathways linked to OA progression were found, offering insights for targeted therapies against OA pain. #PainResearch
📖:
www.sciencedirect.com/science/arti...
📖:
www.sciencedirect.com/science/arti...
Think of transplanting stem cells like sending an athlete onto the field—without
training, they'll struggle. Ai et al. created a "warm-up" system that mechanically pre-trains
MSCs for the tough environment of the knee!
🔗https://www.sciencedirect.com/science/article/pii/S1063458425010659?via%3Dihub
training, they'll struggle. Ai et al. created a "warm-up" system that mechanically pre-trains
MSCs for the tough environment of the knee!
🔗https://www.sciencedirect.com/science/article/pii/S1063458425010659?via%3Dihub
October 22, 2025 at 3:37 PM
Think of transplanting stem cells like sending an athlete onto the field—without
training, they'll struggle. Ai et al. created a "warm-up" system that mechanically pre-trains
MSCs for the tough environment of the knee!
🔗https://www.sciencedirect.com/science/article/pii/S1063458425010659?via%3Dihub
training, they'll struggle. Ai et al. created a "warm-up" system that mechanically pre-trains
MSCs for the tough environment of the knee!
🔗https://www.sciencedirect.com/science/article/pii/S1063458425010659?via%3Dihub
October's #EditorsChoice is on #guthealth
📈 Higher relative abundance of hashtag#alistipessenegalensis and alterations in tryptophan metabolites like indoleacrylic acid are associated with hand hashtag#osteoarthritis
✋ Access full-text and all their awesome figures here: lnkd.in/gPU3RNv7
📈 Higher relative abundance of hashtag#alistipessenegalensis and alterations in tryptophan metabolites like indoleacrylic acid are associated with hand hashtag#osteoarthritis
✋ Access full-text and all their awesome figures here: lnkd.in/gPU3RNv7
October 8, 2025 at 9:15 PM
October's #EditorsChoice is on #guthealth
📈 Higher relative abundance of hashtag#alistipessenegalensis and alterations in tryptophan metabolites like indoleacrylic acid are associated with hand hashtag#osteoarthritis
✋ Access full-text and all their awesome figures here: lnkd.in/gPU3RNv7
📈 Higher relative abundance of hashtag#alistipessenegalensis and alterations in tryptophan metabolites like indoleacrylic acid are associated with hand hashtag#osteoarthritis
✋ Access full-text and all their awesome figures here: lnkd.in/gPU3RNv7
#New in #OAC ! The sphingolipid sphingomyelin 34:1 is upregulated in the synovial fluid of those with OA. Work from @phar.cam.ac.uk shows that SM34:1 causes inflammatory pain in mice, inducing neuronal hyperexcitability.
@psalmotoxin.bsky.social
@interlukein.bsky.social
@mayadannawi.bsky.social
@psalmotoxin.bsky.social
@interlukein.bsky.social
@mayadannawi.bsky.social
October 2, 2025 at 6:03 PM
#New in #OAC ! The sphingolipid sphingomyelin 34:1 is upregulated in the synovial fluid of those with OA. Work from @phar.cam.ac.uk shows that SM34:1 causes inflammatory pain in mice, inducing neuronal hyperexcitability.
@psalmotoxin.bsky.social
@interlukein.bsky.social
@mayadannawi.bsky.social
@psalmotoxin.bsky.social
@interlukein.bsky.social
@mayadannawi.bsky.social
Are you a creative scientist?🧐
#OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩
forms.gle/5qVWiHrHk2G9...
#OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩
forms.gle/5qVWiHrHk2G9...
October 1, 2025 at 4:41 PM
Are you a creative scientist?🧐
#OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩
forms.gle/5qVWiHrHk2G9...
#OAC is looking for a new cover design! Submit your Osteoarthritis and Cartilage based cover designs by November 10th, 2025🤩
forms.gle/5qVWiHrHk2G9...
#New this month in #OAC . Translocator protein 18 kDa (TSPO) plays an important role in #OA occurrence and development. Emapunil targeting TSPO improves OA by modulating #macrophage polarization and #inflammation through the CD14/TLR4/LY96 pathway.
🔗
www.sciencedirect.com/science/arti...
🔗
www.sciencedirect.com/science/arti...
September 29, 2025 at 3:03 PM
#New this month in #OAC . Translocator protein 18 kDa (TSPO) plays an important role in #OA occurrence and development. Emapunil targeting TSPO improves OA by modulating #macrophage polarization and #inflammation through the CD14/TLR4/LY96 pathway.
🔗
www.sciencedirect.com/science/arti...
🔗
www.sciencedirect.com/science/arti...
#New in #OAC This study by Xiao et al. demonstrates that YAP plays a critical role in subchondral bone remodeling and targeting the YAP-Hhip axis through regulation of Hh-Gli1 signaling in Gli1+ osteogenic progenitors could inhibit OA progression! 🐭
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
September 25, 2025 at 2:55 PM
#New in #OAC This study by Xiao et al. demonstrates that YAP plays a critical role in subchondral bone remodeling and targeting the YAP-Hhip axis through regulation of Hh-Gli1 signaling in Gli1+ osteogenic progenitors could inhibit OA progression! 🐭
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
🌟 Four other conditions that should be considered in the differential diagnoses of early-stage symptomatic knee #osteoarthritis (EsSKOA)
1️⃣ Patellofemoral pain
2️⃣ Meniscus injuries
3️⃣ Collateral ligament injuries
4️⃣ Inflammatory arthritis
Read free at lnkd.in/gvKY77uB
1️⃣ Patellofemoral pain
2️⃣ Meniscus injuries
3️⃣ Collateral ligament injuries
4️⃣ Inflammatory arthritis
Read free at lnkd.in/gvKY77uB
September 18, 2025 at 1:40 PM
🌟 Four other conditions that should be considered in the differential diagnoses of early-stage symptomatic knee #osteoarthritis (EsSKOA)
1️⃣ Patellofemoral pain
2️⃣ Meniscus injuries
3️⃣ Collateral ligament injuries
4️⃣ Inflammatory arthritis
Read free at lnkd.in/gvKY77uB
1️⃣ Patellofemoral pain
2️⃣ Meniscus injuries
3️⃣ Collateral ligament injuries
4️⃣ Inflammatory arthritis
Read free at lnkd.in/gvKY77uB
Participants whose daily activity best matched patterns of high evening activity or very high morning activity had the least risk of developing #slowgaitspeed 🚶♂️
🗞️ Read more from Tore et al. oarsijournal.com/article/S1063-…
🗞️ Read more from Tore et al. oarsijournal.com/article/S1063-…
September 15, 2025 at 9:50 AM
Participants whose daily activity best matched patterns of high evening activity or very high morning activity had the least risk of developing #slowgaitspeed 🚶♂️
🗞️ Read more from Tore et al. oarsijournal.com/article/S1063-…
🗞️ Read more from Tore et al. oarsijournal.com/article/S1063-…
NEW in this month's issue 🔥
September's Editors Choice by Akkaya et al. found that diets rich in ultra-processed foods are linked to worse knee #osteoarthritis outcomes especially in women 🍔🍦🍟🍩
👀 Read about this large (n=4403) study for free at: www.oarsijournal.com/article/S106...
September's Editors Choice by Akkaya et al. found that diets rich in ultra-processed foods are linked to worse knee #osteoarthritis outcomes especially in women 🍔🍦🍟🍩
👀 Read about this large (n=4403) study for free at: www.oarsijournal.com/article/S106...
September 5, 2025 at 10:22 PM
NEW in this month's issue 🔥
September's Editors Choice by Akkaya et al. found that diets rich in ultra-processed foods are linked to worse knee #osteoarthritis outcomes especially in women 🍔🍦🍟🍩
👀 Read about this large (n=4403) study for free at: www.oarsijournal.com/article/S106...
September's Editors Choice by Akkaya et al. found that diets rich in ultra-processed foods are linked to worse knee #osteoarthritis outcomes especially in women 🍔🍦🍟🍩
👀 Read about this large (n=4403) study for free at: www.oarsijournal.com/article/S106...
#BasicScience #EditorsChoice
This work by Liao et al. investigated the effects of Tamoxifen in multiple mouse models to better understand its role on bone and cartilage metabolism and endochondral ossification. 🐭
📖Read more:
www.oarsijournal.com/article/S106...
This work by Liao et al. investigated the effects of Tamoxifen in multiple mouse models to better understand its role on bone and cartilage metabolism and endochondral ossification. 🐭
📖Read more:
www.oarsijournal.com/article/S106...
September 3, 2025 at 2:34 PM
#BasicScience #EditorsChoice
This work by Liao et al. investigated the effects of Tamoxifen in multiple mouse models to better understand its role on bone and cartilage metabolism and endochondral ossification. 🐭
📖Read more:
www.oarsijournal.com/article/S106...
This work by Liao et al. investigated the effects of Tamoxifen in multiple mouse models to better understand its role on bone and cartilage metabolism and endochondral ossification. 🐭
📖Read more:
www.oarsijournal.com/article/S106...
🌟 #New in #OAC 🌟
Curious to know how Piezo1 deletion protects against TMJOA?
Read this new work by Wang et al.
sciencedirect.com/science/arti...
Curious to know how Piezo1 deletion protects against TMJOA?
Read this new work by Wang et al.
sciencedirect.com/science/arti...
August 28, 2025 at 11:44 AM
🌟 #New in #OAC 🌟
Curious to know how Piezo1 deletion protects against TMJOA?
Read this new work by Wang et al.
sciencedirect.com/science/arti...
Curious to know how Piezo1 deletion protects against TMJOA?
Read this new work by Wang et al.
sciencedirect.com/science/arti...
📢 Call for Papers
OAC is excited to announce a Special Issue on Pain Mechanisms in Osteoarthritis.
www.sciencedirect.com/special-issu...
Submission Deadline: May 15th, 2026
OAC is excited to announce a Special Issue on Pain Mechanisms in Osteoarthritis.
www.sciencedirect.com/special-issu...
Submission Deadline: May 15th, 2026
August 28, 2025 at 11:24 AM
📢 Call for Papers
OAC is excited to announce a Special Issue on Pain Mechanisms in Osteoarthritis.
www.sciencedirect.com/special-issu...
Submission Deadline: May 15th, 2026
OAC is excited to announce a Special Issue on Pain Mechanisms in Osteoarthritis.
www.sciencedirect.com/special-issu...
Submission Deadline: May 15th, 2026
August 20, 2025 at 1:05 PM
🔥 How can pharmacists help deliver high-value knee OA care?
📖 Explore the #Capabilities, #Opportunities, and #Motivations of Australian pharmacists in this new study: oarsijournal.com/article/S1063-…"
📖 Explore the #Capabilities, #Opportunities, and #Motivations of Australian pharmacists in this new study: oarsijournal.com/article/S1063-…"
August 18, 2025 at 11:33 AM
🔥 How can pharmacists help deliver high-value knee OA care?
📖 Explore the #Capabilities, #Opportunities, and #Motivations of Australian pharmacists in this new study: oarsijournal.com/article/S1063-…"
📖 Explore the #Capabilities, #Opportunities, and #Motivations of Australian pharmacists in this new study: oarsijournal.com/article/S1063-…"
🎙️ New #jointaction podcast on all things #methotrexate
Joint David Hunter with guests Robin Christensen, BSc, MSc, PhD Anna Døssing to learn more 👇
Podcast link: www.jointaction.info/podcast/epis...
Editorial link: pubmed.ncbi.nlm.nih.gov/40222629/
Joint David Hunter with guests Robin Christensen, BSc, MSc, PhD Anna Døssing to learn more 👇
Podcast link: www.jointaction.info/podcast/epis...
Editorial link: pubmed.ncbi.nlm.nih.gov/40222629/
August 7, 2025 at 8:32 PM
🎙️ New #jointaction podcast on all things #methotrexate
Joint David Hunter with guests Robin Christensen, BSc, MSc, PhD Anna Døssing to learn more 👇
Podcast link: www.jointaction.info/podcast/epis...
Editorial link: pubmed.ncbi.nlm.nih.gov/40222629/
Joint David Hunter with guests Robin Christensen, BSc, MSc, PhD Anna Døssing to learn more 👇
Podcast link: www.jointaction.info/podcast/epis...
Editorial link: pubmed.ncbi.nlm.nih.gov/40222629/
New this month!
🦴 Calcium pyrophosphate deposition disease (CPPD) is associated with increased risk of fractures (Fig. 1 below 👇 )
www.oarsijournal.com/action/showP...
🦴 Calcium pyrophosphate deposition disease (CPPD) is associated with increased risk of fractures (Fig. 1 below 👇 )
www.oarsijournal.com/action/showP...
August 6, 2025 at 11:07 AM
New this month!
🦴 Calcium pyrophosphate deposition disease (CPPD) is associated with increased risk of fractures (Fig. 1 below 👇 )
www.oarsijournal.com/action/showP...
🦴 Calcium pyrophosphate deposition disease (CPPD) is associated with increased risk of fractures (Fig. 1 below 👇 )
www.oarsijournal.com/action/showP...
#August #EditorsChoice #BasicScience
This work by Zapata-Linares et al. uses a dynamic mouse model to assess the positive correlation between OA and increased bone marrow adiposity. 📖 more: www.sciencedirect.com/science/arti...
This work by Zapata-Linares et al. uses a dynamic mouse model to assess the positive correlation between OA and increased bone marrow adiposity. 📖 more: www.sciencedirect.com/science/arti...
August 4, 2025 at 2:01 PM
#August #EditorsChoice #BasicScience
This work by Zapata-Linares et al. uses a dynamic mouse model to assess the positive correlation between OA and increased bone marrow adiposity. 📖 more: www.sciencedirect.com/science/arti...
This work by Zapata-Linares et al. uses a dynamic mouse model to assess the positive correlation between OA and increased bone marrow adiposity. 📖 more: www.sciencedirect.com/science/arti...
🏃♂️August's Editor's Choice is on #Taichi
✅ Several benefits associated with #Taichi in this 28 study systematic review that included 1676 OA participants
👀 Read more from Zhao et al. at www.oarsijournal.com/article/S106...
✅ Several benefits associated with #Taichi in this 28 study systematic review that included 1676 OA participants
👀 Read more from Zhao et al. at www.oarsijournal.com/article/S106...
August 2, 2025 at 3:25 AM
🏃♂️August's Editor's Choice is on #Taichi
✅ Several benefits associated with #Taichi in this 28 study systematic review that included 1676 OA participants
👀 Read more from Zhao et al. at www.oarsijournal.com/article/S106...
✅ Several benefits associated with #Taichi in this 28 study systematic review that included 1676 OA participants
👀 Read more from Zhao et al. at www.oarsijournal.com/article/S106...
#New in #OAC MM-II is a dispersion of empty large liposomes which is under clinical development for knee OA. This research by Wechsler et al., aims to decipher the MM-II mechanism of action on the tissue types of the knee joint!
🔗https://sciencedirect.com/science/article/pii/S1063458425008155
🔗https://sciencedirect.com/science/article/pii/S1063458425008155
July 30, 2025 at 1:38 PM
#More #Basic #Science in #OAC Check out this exciting new paper showing TNFalpha receptors-1 & 2 modulate repair potential in painful disc degeneration in a human model system by @iatridislab.bsky.social
🔗https://www.sciencedirect.com/science/article/pii/S1063458425008684?via%3Dihub
🔗https://www.sciencedirect.com/science/article/pii/S1063458425008684?via%3Dihub
July 24, 2025 at 3:03 PM
#More #Basic #Science in #OAC Check out this exciting new paper showing TNFalpha receptors-1 & 2 modulate repair potential in painful disc degeneration in a human model system by @iatridislab.bsky.social
🔗https://www.sciencedirect.com/science/article/pii/S1063458425008684?via%3Dihub
🔗https://www.sciencedirect.com/science/article/pii/S1063458425008684?via%3Dihub