Neuropsychopharmacology
@npp-journal.bsky.social
Neuropsychopharmacology (NPP) is an official peer-reviewed publication of the American College of Neuropsychopharmacology.
We report discoveries and promote training & outreach initiatives.
We report discoveries and promote training & outreach initiatives.
Reposted by Neuropsychopharmacology
Reposted by Neuropsychopharmacology
Congratulations to Michael Gandal, M.D., Ph.D. on being awarded the 2025 Eva King Killam Research Award! 👏 #ACNP2026
Please click here ➡️ tinyurl.com/52447muh to watch the acceptance video by Michael Gandal, M.D., Ph.D.
Please click here ➡️ tinyurl.com/52447muh to watch the acceptance video by Michael Gandal, M.D., Ph.D.
November 21, 2025 at 7:05 PM
Congratulations to Michael Gandal, M.D., Ph.D. on being awarded the 2025 Eva King Killam Research Award! 👏 #ACNP2026
Please click here ➡️ tinyurl.com/52447muh to watch the acceptance video by Michael Gandal, M.D., Ph.D.
Please click here ➡️ tinyurl.com/52447muh to watch the acceptance video by Michael Gandal, M.D., Ph.D.
Reposted by Neuropsychopharmacology
Congratulations to Harriet De Wit, Ph.D., for being awarded the Barbara Fish Memorial Award! ☺️ #ACNP2026
Please click here ➡️tinyurl.com/2ndexz5k to watch the nominator video by Abraham Palmer, Ph.D.
Please click here ➡️tinyurl.com/2ndexz5k to watch the nominator video by Abraham Palmer, Ph.D.
November 21, 2025 at 7:10 PM
Congratulations to Harriet De Wit, Ph.D., for being awarded the Barbara Fish Memorial Award! ☺️ #ACNP2026
Please click here ➡️tinyurl.com/2ndexz5k to watch the nominator video by Abraham Palmer, Ph.D.
Please click here ➡️tinyurl.com/2ndexz5k to watch the nominator video by Abraham Palmer, Ph.D.
In this perspective, a mother recounts her son’s struggle with severe childhood mental illness, marked by shifting diagnoses/medications & persisting symptoms, despite expert care; she calls for more rigor in diagnosing & treating pediatric mental illness
There is still so much work to be done: a mother’s perspective
Neuropsychopharmacology - There is still so much work to be done: a mother’s perspective
www.nature.com
November 21, 2025 at 5:29 PM
In this perspective, a mother recounts her son’s struggle with severe childhood mental illness, marked by shifting diagnoses/medications & persisting symptoms, despite expert care; she calls for more rigor in diagnosing & treating pediatric mental illness
This recent 🔥 Hot Topic 🔥 highlights new insights into how the lateral septum regulates social behavior via the amygdala & PFC
Cross-species molecular studies suggest conserved mechanisms that may underlie social dysfunction in psychiatric disorders
Cross-species molecular studies suggest conserved mechanisms that may underlie social dysfunction in psychiatric disorders
Role of molecularly defined lateral septum cell types and circuits in social behaviors
Neuropsychopharmacology - Role of molecularly defined lateral septum cell types and circuits in social behaviors
www.nature.com
November 20, 2025 at 4:28 PM
This recent 🔥 Hot Topic 🔥 highlights new insights into how the lateral septum regulates social behavior via the amygdala & PFC
Cross-species molecular studies suggest conserved mechanisms that may underlie social dysfunction in psychiatric disorders
Cross-species molecular studies suggest conserved mechanisms that may underlie social dysfunction in psychiatric disorders
This recent 🔥 Hot Topic 🔥 highlights how brain bioenergetics (regulation of energy metabolism & mitochondrial function) drive psychiatric vulnerability, highlighting metabolic interventions that may ⬆️ energetic balance & support 🧠 development
Fueling the future: brain bioenergetics as a driver of neurodevelopment and mental health trajectories
Neuropsychopharmacology - Fueling the future: brain bioenergetics as a driver of neurodevelopment and mental health trajectories
www.nature.com
November 19, 2025 at 3:31 PM
This recent 🔥 Hot Topic 🔥 highlights how brain bioenergetics (regulation of energy metabolism & mitochondrial function) drive psychiatric vulnerability, highlighting metabolic interventions that may ⬆️ energetic balance & support 🧠 development
Reposted by Neuropsychopharmacology
Congrats to @pact-lab.bsky.social postdoc @ryanntansey.bsky.social on receiving an @acnporg.bsky.social Travel Award! 🎉
#ACNP2026
#ACNP2026
Here is Week #1 installment for @acnporg.bsky.social Travel Awardees of #ACNP2026
Dr. Mia Rough, Wake Forest University
Dr. Clara Zundel, Wayne State University
Dr. Ryann Tansey, University of Calgary
Dr. Alexander Herman, University of Minnesota
@clarazundel.bsky.social
@ryanntansey.bsky.social
Dr. Mia Rough, Wake Forest University
Dr. Clara Zundel, Wayne State University
Dr. Ryann Tansey, University of Calgary
Dr. Alexander Herman, University of Minnesota
@clarazundel.bsky.social
@ryanntansey.bsky.social
November 18, 2025 at 4:15 PM
Congrats to @pact-lab.bsky.social postdoc @ryanntansey.bsky.social on receiving an @acnporg.bsky.social Travel Award! 🎉
#ACNP2026
#ACNP2026
Get ready, another installment of #ThisWeekinNPP is incoming 🚀
See below for the newest insights on the relationships between neuromelanin & schizophrenia, BDNF & alcohol, and the impact of a high-fat diet on microglia 👇
See below for the newest insights on the relationships between neuromelanin & schizophrenia, BDNF & alcohol, and the impact of a high-fat diet on microglia 👇
November 18, 2025 at 9:18 PM
Get ready, another installment of #ThisWeekinNPP is incoming 🚀
See below for the newest insights on the relationships between neuromelanin & schizophrenia, BDNF & alcohol, and the impact of a high-fat diet on microglia 👇
See below for the newest insights on the relationships between neuromelanin & schizophrenia, BDNF & alcohol, and the impact of a high-fat diet on microglia 👇
This recent 🔥 Hot Topic 🔥 discusses how AI-assisted decision-support systems - including large language models - could strengthen mental health care in conflict zones by supporting clinician reasoning & consistency under extreme stress
Digital frontlines: leveraging AI to augment human expertise in crisis and combat situations
Neuropsychopharmacology - Digital frontlines: leveraging AI to augment human expertise in crisis and combat situations
www.nature.com
November 18, 2025 at 4:31 PM
This recent 🔥 Hot Topic 🔥 discusses how AI-assisted decision-support systems - including large language models - could strengthen mental health care in conflict zones by supporting clinician reasoning & consistency under extreme stress
Reposted by Neuropsychopharmacology
So excited to be a part of this stellar group of travel awardees this year!! See you at #ACNP2026 🏝️☀️🔬
Here is Week #1 installment for @acnporg.bsky.social Travel Awardees of #ACNP2026
Dr. Mia Rough, Wake Forest University
Dr. Clara Zundel, Wayne State University
Dr. Ryann Tansey, University of Calgary
Dr. Alexander Herman, University of Minnesota
@clarazundel.bsky.social
@ryanntansey.bsky.social
Dr. Mia Rough, Wake Forest University
Dr. Clara Zundel, Wayne State University
Dr. Ryann Tansey, University of Calgary
Dr. Alexander Herman, University of Minnesota
@clarazundel.bsky.social
@ryanntansey.bsky.social
November 18, 2025 at 2:44 PM
So excited to be a part of this stellar group of travel awardees this year!! See you at #ACNP2026 🏝️☀️🔬
We're < 2 months away from #ACNP2026, so it's time to start the countdown @npp-journal.bsky.social journal style: by highlighting the fantastic @acnporg.bsky.social Travel Awardees who will be attending 🤩
a man with long curly hair is wearing a la sweatshirt and says you ready .
ALT: a man with long curly hair is wearing a la sweatshirt and says you ready .
media.tenor.com
November 17, 2025 at 9:18 PM
We're < 2 months away from #ACNP2026, so it's time to start the countdown @npp-journal.bsky.social journal style: by highlighting the fantastic @acnporg.bsky.social Travel Awardees who will be attending 🤩
This recent 🔃 Review 🔃 examines how structural racism is embedded in nearly every sector of society, creating social & environmental contextual drivers that affect mental & physical health of minoritized populations
A review of the impact of structural racism on lived experiences of adolescents of African descent: Implications for development, brain structure, and health
Neuropsychopharmacology - A review of the impact of structural racism on lived experiences of adolescents of African descent: Implications for development, brain structure, and health
www.nature.com
November 17, 2025 at 5:31 PM
This recent 🔃 Review 🔃 examines how structural racism is embedded in nearly every sector of society, creating social & environmental contextual drivers that affect mental & physical health of minoritized populations
Reposted by Neuropsychopharmacology
This paper describes outreach efforts on X. Now that Elon’s fascist leanings and algorithms are so obvious, why is NPP still using X? You should stop immediately and rely on Bluesky to drive engagement. Stop supporting rapacious fascists in our name!
This paper, led by former NPP intern Hayley Thorpe, tracks the impact of our NPP social media efforts (which we are now sharing on social media - so meta!) on facilitating engagement with articles and driving website traffic
Optimizing social media initiatives to promote Neuropsychopharmacology (NPP) publications
Neuropsychopharmacology - Optimizing social media initiatives to promote Neuropsychopharmacology (NPP) publications
www.nature.com
November 7, 2025 at 5:37 PM
This paper describes outreach efforts on X. Now that Elon’s fascist leanings and algorithms are so obvious, why is NPP still using X? You should stop immediately and rely on Bluesky to drive engagement. Stop supporting rapacious fascists in our name!
Reposted by Neuropsychopharmacology
We are proud to announce ACNP's NPP Journal award winners! Dhvani D. Mehta, B.Sc. (NEATOR Award), John H. Krystal, M.D. (NEAR Award), and Max E. Joffe, Ph.D. @mejoffe (NEECA Award) @npp-journal.bsky.social, #ACNP2026
November 10, 2025 at 3:00 PM
We are proud to announce ACNP's NPP Journal award winners! Dhvani D. Mehta, B.Sc. (NEATOR Award), John H. Krystal, M.D. (NEAR Award), and Max E. Joffe, Ph.D. @mejoffe (NEECA Award) @npp-journal.bsky.social, #ACNP2026
Reposted by Neuropsychopharmacology
Fascinating study, you can also read my Research Highlight on this paper and connectome harmonics here pubmed.ncbi.nlm.nih.gov/40940590/
This recent study finds that DMT reshapes the 🧠’s connectome harmonic repertoire, mirroring effects of psilocybin, LSD & ketamine, with entropy and energy spectrum changes closely tracking the intensity of participants’ subjective experiences 🍄💊
N,N-dimethyltryptamine effects on connectome harmonics, subjective experience and comparative psychedelic experiences
Neuropsychopharmacology - N,N-dimethyltryptamine effects on connectome harmonics, subjective experience and comparative psychedelic experiences
www.nature.com
November 11, 2025 at 1:34 PM
Fascinating study, you can also read my Research Highlight on this paper and connectome harmonics here pubmed.ncbi.nlm.nih.gov/40940590/
Reposted by Neuropsychopharmacology
Congratulations to Dhvani D. Mehta, BSc for being awarded the NEATOR Award, The Neuropsychopharmacology Editors' Award for a Transformative Original Report @npp-journal.bsky.social
November 11, 2025 at 4:00 PM
Congratulations to Dhvani D. Mehta, BSc for being awarded the NEATOR Award, The Neuropsychopharmacology Editors' Award for a Transformative Original Report @npp-journal.bsky.social
Reposted by Neuropsychopharmacology
Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧵
November 11, 2025 at 8:01 PM
Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧵
Reposted by Neuropsychopharmacology
Congratulations to John H. Krystal, M.D. for being awarded the NEAR Award for the top review paper published in print in @npp-journal.bsky.social in 2024, tinyurl.com/3a6ea5wf!
November 12, 2025 at 4:00 PM
Congratulations to John H. Krystal, M.D. for being awarded the NEAR Award for the top review paper published in print in @npp-journal.bsky.social in 2024, tinyurl.com/3a6ea5wf!
Reposted by Neuropsychopharmacology
Check out his acceptance video at tinyurl.com/mwzwt9yv and a video in support by Marianne Seney, Ph.D. at tinyurl.com/mrxkwckh @npp-journal.bsky.social #ACNP2026
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Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
tinyurl.com
November 13, 2025 at 4:00 PM
Check out his acceptance video at tinyurl.com/mwzwt9yv and a video in support by Marianne Seney, Ph.D. at tinyurl.com/mrxkwckh @npp-journal.bsky.social #ACNP2026
This recent paper found that striatal neuroinflammation may promote maladaptive goal-directed behaviors, challenging the view that compulsivity arises solely from habit dominance
Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function
Neuropsychopharmacology - Dorsomedial striatal neuroinflammation causes excessive goal-directed action control by disrupting astrocyte function
www.nature.com
November 14, 2025 at 5:31 PM
This recent paper found that striatal neuroinflammation may promote maladaptive goal-directed behaviors, challenging the view that compulsivity arises solely from habit dominance
This recent 🔃 Review 🔃 discusses how computational psychiatry can reveal latent mechanisms in ADHD & mood disorders, emphasizing ways to ⬆️ reliability & develop more precise, ecologically valid models for diagnosis & treatment
From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry
Neuropsychopharmacology - From symptom-based heterogeneity to mechanism-based profiling in youth ADHD: the promise of computational psychiatry
www.nature.com
November 13, 2025 at 4:26 PM
This recent 🔃 Review 🔃 discusses how computational psychiatry can reveal latent mechanisms in ADHD & mood disorders, emphasizing ways to ⬆️ reliability & develop more precise, ecologically valid models for diagnosis & treatment
In this correspondence, authors warn that multiple studies misidentified PF-05231023, using a commercial small molecule instead of Pfizer’s intended Fc-conjugated FGF21 analog CVX-343, resulting in misattribution of biological effects to FGF21 signaling
Namesake of PF-05231023: how nomenclature confusion leads to experimental misinterpretation in pharmacologic research
Neuropsychopharmacology - Namesake of PF-05231023: how nomenclature confusion leads to experimental misinterpretation in pharmacologic research
www.nature.com
November 12, 2025 at 3:31 PM
In this correspondence, authors warn that multiple studies misidentified PF-05231023, using a commercial small molecule instead of Pfizer’s intended Fc-conjugated FGF21 analog CVX-343, resulting in misattribution of biological effects to FGF21 signaling
This study examined genetic risk for treatment-resistant depression in the Taiwan Biobank and compared polygenic score associations with European data, with some trait-specific associations differing between East Asian and European groups
Comparative polygenic predispositions of treatment-resistant depression in East Asian and European populations
Neuropsychopharmacology - Comparative polygenic predispositions of treatment-resistant depression in East Asian and European populations
www.nature.com
November 11, 2025 at 4:30 PM
This study examined genetic risk for treatment-resistant depression in the Taiwan Biobank and compared polygenic score associations with European data, with some trait-specific associations differing between East Asian and European groups
It's Tuesday again - fresh reads, sharp minds, new #ThisWeekInNPP 🧠
This week we are back with insights on trauma, development, and psychedelics.
🧵👇
This week we are back with insights on trauma, development, and psychedelics.
🧵👇
November 11, 2025 at 2:00 PM
It's Tuesday again - fresh reads, sharp minds, new #ThisWeekInNPP 🧠
This week we are back with insights on trauma, development, and psychedelics.
🧵👇
This week we are back with insights on trauma, development, and psychedelics.
🧵👇
This recent ✨ Research Highlight ✨ discusses a recent study showing IV DMT shifts 🧠 dynamics measured by connectome harmonics, with effects that mirror LSD & psilocybin and contrast with unconscious states
www.nature.com/artic...
OG article:
www.nature.com/artic...
OG article:
Connectome harmonics: a novel method exploring the psychedelic experience
Neuropsychopharmacology - Connectome harmonics: a novel method exploring the psychedelic experience
www.nature.com
November 10, 2025 at 5:31 PM
This recent ✨ Research Highlight ✨ discusses a recent study showing IV DMT shifts 🧠 dynamics measured by connectome harmonics, with effects that mirror LSD & psilocybin and contrast with unconscious states
www.nature.com/artic...
OG article:
www.nature.com/artic...
OG article: