Nora Fresmann
norafrenaline.bsky.social
Nora Fresmann
@norafrenaline.bsky.social
Systems biology PhD student working at the bench & behind the desk @mdc-bimsb.bsky.social
Interested in cancer & developmental biology.
Reposted by Nora Fresmann
Science 🤝 Art 🤝 Zebrafish

👉#ZebrafishZunday 🧪
Zebrafish embryo undergoing gastrulation. Credit to Dr. Gopi Shah at EMBL. #ZebrafishZunday 🧪
October 19, 2025 at 6:02 PM
Reposted by Nora Fresmann
Distinct tumor immune microenvironmental (TIME) landscapes drive divergent immunotherapy responses in glioblastoma https://www.biorxiv.org/content/10.1101/2025.10.18.683203v1
October 20, 2025 at 3:48 AM
Reposted by Nora Fresmann
New preprint! Using single-cell lineage tracing in zebrafish, the Junker lab shows how neuroblastoma cell states arise and change: tumor states are partly determined by the cell of origin, yet retain plastic potential and can be reprogrammed in developmental environments.
biorxiv.org/content/10.1...
Lineage origin and microenvironment shape neuroblastoma transcriptional state and plasticity
Neuroblastoma, a neural-crest-derived malignancy of the peripheral nervous system, is a devastating pediatric disease, characterized by high intra- and intertumoral heterogeneity. While expression of ...
biorxiv.org
October 16, 2025 at 3:52 PM