Noa Guzzi
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noagzz.bsky.social
Noa Guzzi
@noagzz.bsky.social
PhD student in @institutpasteur - Laboratory : Bacterial Genome Plasticity (PGB) - working on V. cholerae genome
Reposted by Noa Guzzi
Our new paper is out in @narjournal.bsky.social We show that natural transformation enables bacteria to shuffle integron cassettes, boosting their phenotypic diversity.
academic.oup.com/nar/article/... 1/5
Bacterial natural transformation drives cassette shuffling and simplifies recombination in chromosomal integrons
Abstract. Integrons act as biobanks of gene cassettes conferring functions crucial for bacterial defense, including protection against phages and antibioti
academic.oup.com
November 17, 2025 at 3:44 PM
Reposted by Noa Guzzi
Our new paper maps the tRNA modification landscape in Vibrio cholerae! 💫
We describe differences from E. coli and discuss links to decoding of stress-related codons 🦠
Huge thanks to amazing co-authors and collaborators!
@plos.org #rnasky #microsky #tRNAmodifications
The tRNA epitranscriptomic landscape and RNA modification enzymes in Vibrio cholerae
Author summary This study charts the first genome-wide map of transfer RNA (tRNA) modifications in the cholera pathogen, Vibrio cholerae, revealing how chemical marks on tRNAs shape translation and st...
journals.plos.org
November 3, 2025 at 11:58 PM
Reposted by Noa Guzzi
So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!
Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters
Uridine boosts aminoglycoside treatment efficiency against antibiotic-susceptible as well as antibiotic-resistant E. coli strains.
www.science.org
September 6, 2025 at 9:35 AM
Reposted by Noa Guzzi
For those who love bacterial replicons, The ultimate review, from our lab, signed by the master of their evolution.
‪@val-meve.bsky.social‬ www.sciencedirect.com/science/arti...
Taming wild replicons: evolution and domestication of large extrachromosomal replicons
Bacterial genomes often contain extrachromosomal replicons (ERs), ranging from small, mobile plasmids to large, stably inherited elements, such as meg…
www.sciencedirect.com
August 20, 2025 at 10:28 AM
Reposted by Noa Guzzi
📢 Postdoctoral research position

A 2-year postdoctoral position on bacteriophages research is available at the Institut Pasteur in Paris in the Plasticity of the Genomes Unit.

🧐 Those interested can now send their applications!
July 28, 2025 at 9:06 AM
Reposted by Noa Guzzi
📢Aujourd'hui l'Institut Pasteur se mobilise pour la science, l'inclusion & l'avenir du savoir avec l'organisation du symposium «Excellence Scientifique : et si l'inclusion était la clé ?» en écho avec la Journée Internationale des Droits des Femme & la participation au mouvement #StandUpForScience !
March 7, 2025 at 2:23 PM