Nina Donner, PhD
@ninadonner.bsky.social
About me:
Science Communicator, Project Manager, Researcher, Nature Lover
Position at concentris research management gmbh:
Empowering European science and innovation with
#GrantWriting
#ProjectManagement
#ScienceCommunication
#Dissemination
Science Communicator, Project Manager, Researcher, Nature Lover
Position at concentris research management gmbh:
Empowering European science and innovation with
#GrantWriting
#ProjectManagement
#ScienceCommunication
#Dissemination
Reposted by Nina Donner, PhD
Reposted by Nina Donner, PhD
5️⃣ García-Blanco et al. (2002): www.jci.org/articles/vie...
📖 miRNA signatures associated with vulnerability to food addiction in mice & humans
💡Common #miRNA #signatures in mice & humans may underlie vulnerability to #FoodAddiction.
💡Targeting those miRNAs may modify maladaptive eating phenotypes.
📖 miRNA signatures associated with vulnerability to food addiction in mice & humans
💡Common #miRNA #signatures in mice & humans may underlie vulnerability to #FoodAddiction.
💡Targeting those miRNAs may modify maladaptive eating phenotypes.
JCI -
miRNA signatures associated with vulnerability to food addiction in mice and humans
www.jci.org
October 3, 2025 at 6:27 PM
5️⃣ García-Blanco et al. (2002): www.jci.org/articles/vie...
📖 miRNA signatures associated with vulnerability to food addiction in mice & humans
💡Common #miRNA #signatures in mice & humans may underlie vulnerability to #FoodAddiction.
💡Targeting those miRNAs may modify maladaptive eating phenotypes.
📖 miRNA signatures associated with vulnerability to food addiction in mice & humans
💡Common #miRNA #signatures in mice & humans may underlie vulnerability to #FoodAddiction.
💡Targeting those miRNAs may modify maladaptive eating phenotypes.
Reposted by Nina Donner, PhD
4️⃣ academic.oup.com/ismej/articl...
📖 Presence of #Blastocystis in #GutMicrobiota associated with decreased executive function
💡Blastocystis colonisation in the gut is associated with measurable deficits in executive #CognitiveFunction, suggesting a possible #GutBrainAxis influence on cognition.
📖 Presence of #Blastocystis in #GutMicrobiota associated with decreased executive function
💡Blastocystis colonisation in the gut is associated with measurable deficits in executive #CognitiveFunction, suggesting a possible #GutBrainAxis influence on cognition.
Presence of Blastocystis in gut microbiota is associated with cognitive traits and decreased executive function
AbstractGrowing evidence implicates the gut microbiome in cognition. Blastocystis is a common gut single-cell eukaryote parasite frequently detected in hum
academic.oup.com
October 3, 2025 at 6:22 PM
4️⃣ academic.oup.com/ismej/articl...
📖 Presence of #Blastocystis in #GutMicrobiota associated with decreased executive function
💡Blastocystis colonisation in the gut is associated with measurable deficits in executive #CognitiveFunction, suggesting a possible #GutBrainAxis influence on cognition.
📖 Presence of #Blastocystis in #GutMicrobiota associated with decreased executive function
💡Blastocystis colonisation in the gut is associated with measurable deficits in executive #CognitiveFunction, suggesting a possible #GutBrainAxis influence on cognition.
Reposted by Nina Donner, PhD
3️⃣ doi.org/10.3389/fpsy...
📖 Tetrahydrocannabinol #THC exposure in #adolescence elevates #impulsivity-like behaviour in #adulthood in a self-administration mouse model
💡Young-age THC exposure may produce a lasting impulsivity increase & neurochemical changes that predispose to #AddictiveBehaviour.
📖 Tetrahydrocannabinol #THC exposure in #adolescence elevates #impulsivity-like behaviour in #adulthood in a self-administration mouse model
💡Young-age THC exposure may produce a lasting impulsivity increase & neurochemical changes that predispose to #AddictiveBehaviour.
Frontiers | THC exposure during adolescence increases impulsivity-like behavior in adulthood in a WIN 55,212-2 self-administration mouse model
Cannabis addiction is a chronically relapsing disorder lacking effective treatment. Regular cannabis consumption typically begins during adolescence, and thi...
doi.org
October 3, 2025 at 6:18 PM
3️⃣ doi.org/10.3389/fpsy...
📖 Tetrahydrocannabinol #THC exposure in #adolescence elevates #impulsivity-like behaviour in #adulthood in a self-administration mouse model
💡Young-age THC exposure may produce a lasting impulsivity increase & neurochemical changes that predispose to #AddictiveBehaviour.
📖 Tetrahydrocannabinol #THC exposure in #adolescence elevates #impulsivity-like behaviour in #adulthood in a self-administration mouse model
💡Young-age THC exposure may produce a lasting impulsivity increase & neurochemical changes that predispose to #AddictiveBehaviour.
Reposted by Nina Donner, PhD
2️⃣García-Blanco et al., 2023 www.sciencedirect.com/science/arti...
📖 #CB2 #CannabinoidReceptor & the development of food addiction in mice
💡CB2R is a modulatory node in the control of hedonic feeding and vulnerability to #FoodAddiction, making it a potential therapeutic target for eating disorders
📖 #CB2 #CannabinoidReceptor & the development of food addiction in mice
💡CB2R is a modulatory node in the control of hedonic feeding and vulnerability to #FoodAddiction, making it a potential therapeutic target for eating disorders
Role of CB2 cannabinoid receptor in the development of food addiction in male mice
The endocannabinoid system plays an important role in multiple behavioral responses due to its wide distribution in the central nervous system. The ca…
www.sciencedirect.com
October 3, 2025 at 6:12 PM
2️⃣García-Blanco et al., 2023 www.sciencedirect.com/science/arti...
📖 #CB2 #CannabinoidReceptor & the development of food addiction in mice
💡CB2R is a modulatory node in the control of hedonic feeding and vulnerability to #FoodAddiction, making it a potential therapeutic target for eating disorders
📖 #CB2 #CannabinoidReceptor & the development of food addiction in mice
💡CB2R is a modulatory node in the control of hedonic feeding and vulnerability to #FoodAddiction, making it a potential therapeutic target for eating disorders
Reposted by Nina Donner, PhD
1️⃣ Del Mar Cajiao-Manrique, Maldonado & Martín-García (2023) doi.org/10.3389/fpha...
📖 A self-administration mouse model to study #CannabinoidAddiction
💡This novel #MouseModel provides a rigorous tool to study #CannabinoidAddiction & the neurobiological mechanisms of #vulnerability vs. #resilience.
📖 A self-administration mouse model to study #CannabinoidAddiction
💡This novel #MouseModel provides a rigorous tool to study #CannabinoidAddiction & the neurobiological mechanisms of #vulnerability vs. #resilience.
Frontiers | A male mouse model of WIN 55,212–2 self-administration to study cannabinoid addiction
We have established for the first time a mouse model of cannabinoid addiction using WIN 55,212-2 intravenous self-administration (0.0125 mg/kg/infusion) in C...
doi.org
October 3, 2025 at 6:04 PM
1️⃣ Del Mar Cajiao-Manrique, Maldonado & Martín-García (2023) doi.org/10.3389/fpha...
📖 A self-administration mouse model to study #CannabinoidAddiction
💡This novel #MouseModel provides a rigorous tool to study #CannabinoidAddiction & the neurobiological mechanisms of #vulnerability vs. #resilience.
📖 A self-administration mouse model to study #CannabinoidAddiction
💡This novel #MouseModel provides a rigorous tool to study #CannabinoidAddiction & the neurobiological mechanisms of #vulnerability vs. #resilience.
Reposted by Nina Donner, PhD
A more #PainRelief-relevant follow-up of the 2020 Sci. Rep. paper is this article by Ricarte, Dalton & Giraldo (2021), a year later:
🔗 doi.org/10.1021/acs....
🧬 Structural assessment of #agonist #efficacy at the μ-opioid receptor #MOR
👉 #morphine and #fentanyl elicit different activation patterns
🔗 doi.org/10.1021/acs....
🧬 Structural assessment of #agonist #efficacy at the μ-opioid receptor #MOR
👉 #morphine and #fentanyl elicit different activation patterns
October 3, 2025 at 4:21 PM
A more #PainRelief-relevant follow-up of the 2020 Sci. Rep. paper is this article by Ricarte, Dalton & Giraldo (2021), a year later:
🔗 doi.org/10.1021/acs....
🧬 Structural assessment of #agonist #efficacy at the μ-opioid receptor #MOR
👉 #morphine and #fentanyl elicit different activation patterns
🔗 doi.org/10.1021/acs....
🧬 Structural assessment of #agonist #efficacy at the μ-opioid receptor #MOR
👉 #morphine and #fentanyl elicit different activation patterns
Reposted by Nina Donner, PhD
Here's another important QSPainRelief publication about allosteric sites at #GPCRs: They can be identified by looking at how strongly certain receptor sites are coupled to #conformational changes that occur during activation.
🔗 doi.org/10.3390/ijms...
#allostery #pharmacology #receptors #ligands
🔗 doi.org/10.3390/ijms...
#allostery #pharmacology #receptors #ligands
October 3, 2025 at 3:31 PM
Here's another important QSPainRelief publication about allosteric sites at #GPCRs: They can be identified by looking at how strongly certain receptor sites are coupled to #conformational changes that occur during activation.
🔗 doi.org/10.3390/ijms...
#allostery #pharmacology #receptors #ligands
🔗 doi.org/10.3390/ijms...
#allostery #pharmacology #receptors #ligands
Reposted by Nina Donner, PhD
Speaking of #allostery: What happens when you mutate the #CannabinoidReceptor (CB1) in silico with a single-point mutation?
Find out👉: doi.org/10.1021/acso...
Spoiler😉: The F237L mutation mimics #allosteric #ligand effects, globally altering #receptor conformations and hindering activation
#GPCR
Find out👉: doi.org/10.1021/acso...
Spoiler😉: The F237L mutation mimics #allosteric #ligand effects, globally altering #receptor conformations and hindering activation
#GPCR
October 3, 2025 at 1:31 PM
Speaking of #allostery: What happens when you mutate the #CannabinoidReceptor (CB1) in silico with a single-point mutation?
Find out👉: doi.org/10.1021/acso...
Spoiler😉: The F237L mutation mimics #allosteric #ligand effects, globally altering #receptor conformations and hindering activation
#GPCR
Find out👉: doi.org/10.1021/acso...
Spoiler😉: The F237L mutation mimics #allosteric #ligand effects, globally altering #receptor conformations and hindering activation
#GPCR
Reposted by Nina Donner, PhD
The paper by Budda et al. (2024) relates to the earlier publication by Gülave et al. (2023): doi.org/10.1016/j.ej...
🧠The transport of #morphine across the #BBB is non-linear - this is important for #receptor #occupancy predictions. Find out how BBB dynamics inform smarter, safer dosing strategies!
🧠The transport of #morphine across the #BBB is non-linear - this is important for #receptor #occupancy predictions. Find out how BBB dynamics inform smarter, safer dosing strategies!
October 3, 2025 at 11:19 AM
The paper by Budda et al. (2024) relates to the earlier publication by Gülave et al. (2023): doi.org/10.1016/j.ej...
🧠The transport of #morphine across the #BBB is non-linear - this is important for #receptor #occupancy predictions. Find out how BBB dynamics inform smarter, safer dosing strategies!
🧠The transport of #morphine across the #BBB is non-linear - this is important for #receptor #occupancy predictions. Find out how BBB dynamics inform smarter, safer dosing strategies!