Nico Hüttmann
@nicohuettmann.bsky.social
PhD student in the Savitski Team @EMBL Heidelberg. Alum Berezovski lab and JLHMS facility @uOttawa, @TUDarmstadt. Handball and Tennis and more coming
Reposted by Nico Hüttmann
Finally out! 🤩 Check out our HT- PELSA for high throughput screening！
Happy to see our HT-PELSA paper now published in @natsmb.nature.com 🎊 Big thanks for the constructive review process! 📖Read the manuscript here (www.nature.com/articles/s41...) & check the thread for additional information ⬇️
November 5, 2025 at 4:28 PM
Finally out! 🤩 Check out our HT- PELSA for high throughput screening！
Reposted by Nico Hüttmann
Want to know how the ligands interact with proteins beyond model cell lines, e.g., in tissues or bacteria? Interested in membrane targets? Check out our High-Throughput PELSA method which allows you do all these cool screenings for dozens of ligands within two hours! www.biorxiv.org/content/10.1...
High-throughput peptide-centric local stability assay extends protein-ligand identification to membrane proteins, tissues, and bacteria
Systematic mapping of protein-ligand interactions is essential for understanding biological processes and drug mechanisms. Peptide-centric local stability assay (PELSA) is a powerful tool for detectin...
www.biorxiv.org
April 29, 2025 at 6:13 PM
Want to know how the ligands interact with proteins beyond model cell lines, e.g., in tissues or bacteria? Interested in membrane targets? Check out our High-Throughput PELSA method which allows you do all these cool screenings for dozens of ligands within two hours! www.biorxiv.org/content/10.1...