In children with septic shock and no known cardiac dysfunction, starting treatment with norepinephrine rather than epinephrine was associated with lower 30-day mortality.

#CCR25 #MedSky

ja.ma/4kXryTp

Intravenous hydrocortisone was associated with a reduced need for new kidney replacement therapy in patients with septic shock.

#CCR25 #MedSky

ja.ma/3SLC3xg

I think that could work just fine, especially given the kinetics of NfL compared w some of the other biomarkers, some of which peak early enough that they may not help after 72h.

Not in this dataset, but we are currently doing a randomized trial of SGA vs BVM placed by FF/EMTs for OHCA that will
include some fairly detailed ventilation meaurements in both arms. Different question
somewhat, but we hope helpful: clinicaltrials.gov/study/NCT059...

agree w others. benefit, if any, is not immediate, but a small reduction in long-term neurological sequelae. seems that propensity to use depends on ease of access to appropriate chamber.

Not exactly what you want but at least a little lower threshold for potassium supplementation after cardiac surgery - 3.5 v 4.5

pubmed.ncbi.nlm.nih.gov/39215972/

Thank you! And many thanks for these awesome lists!!

Oh hey!