@nicholas-aboreden.bsky.social
PhD candidate at UPenn/CHOP. 3D Genomics | Enhancer/Promoter communication.
Reposted
(3/n) Do mitotic microcompartments have a transcriptional function?
Prior work from @chrishsiung.bsky.social Gerd Blobel discovered 'mitotic transcriptional spiking', where ~half of genes transcriptionally spike in mitosis.
We now show that microcompartment dot number and strength predicts spiking
Prior work from @chrishsiung.bsky.social Gerd Blobel discovered 'mitotic transcriptional spiking', where ~half of genes transcriptionally spike in mitosis.
We now show that microcompartment dot number and strength predicts spiking
October 20, 2025 at 6:45 PM
(3/n) Do mitotic microcompartments have a transcriptional function?
Prior work from @chrishsiung.bsky.social Gerd Blobel discovered 'mitotic transcriptional spiking', where ~half of genes transcriptionally spike in mitosis.
We now show that microcompartment dot number and strength predicts spiking
Prior work from @chrishsiung.bsky.social Gerd Blobel discovered 'mitotic transcriptional spiking', where ~half of genes transcriptionally spike in mitosis.
We now show that microcompartment dot number and strength predicts spiking