exploring something new? some might say there is still enough to exploit in with this terminology 🙃

Thanks to @intlbrainlab.bsky.social for assembling and sharing their data!! And this work was mainly the work of Xingyun Wang.

I’ve often made the bet that we’ll never really understand what’s in the LFP (or the EEG). While I feel these findings leave me with many many further questions, I don’t think I’ll make that bet again.

What technique did we use? We extracted second long spectrograms and used deep learning to localize each sample. We checked that the deep nets could generalize to new experiments and new animals. We then used the confusion matrix as a graph and searched for highly interconnected groups.

Graphs highlighted resemblance between communities sometimes hinged on pairs areas. Here are examples of such pairs between communities involving the motor planning community.

The largest community outside the cerebellum and hindbrain contained parts of the basal ganglia (putamen and nucleus accumbens) and motor planning regions of cortex (ACA, GU, MOs, MOp, ORB). It split in two during visual task.

This atlas of the local field potentials showed much re-organization when comparing rest and the visual+wheel turning task. Among many interesting changes, not only did the core visual communities grew larger, a new community highlighted ressemblence of tactile areas for upper and lower limbs.

For instance, the visual layers of superior colliculus were most similar to primary cortex as well as other visual areas such as VISpm & VISa, retrosplenial and area poststriata (hippocampal). The motor parts of the superior colliculus were most similar to noncortical oculomotor areas

Maybe I was naïve, I honestly thought we would only see a smooth and blurry transition between the frontal cortex, visual cortex and the hippocampus. But the structure we found was finer grained, more functional and more dynamic than I thought.