Joshua Jacobs
Joshua Jacobs
@neurojosh.bsky.social
I study the human brain with virtual reality and high-def monitors. Professor at the University of Chicago.
I have moved my lab to @uchicago! Really excited to be here and collaborate with all the wonderful scientists and clinicians here.
September 24, 2025 at 5:50 PM
Reposted by Joshua Jacobs
🧠 Paper out!

We investigated how hippocampal and cortical ripples support memory during movie watching. We found that:

🎬 Hippocampal ripples mark event boundaries
🧩 Cortical ripples predict later recall

Ripples may help transform real-life experiences into lasting memories!

rdcu.be/eui9l
Movie-watching evokes ripple-like activity within events and at event boundaries
Nature Communications - The neural processes involved in memory formation for realistic experiences remain poorly understood. Here, the authors found that ripple-like activity in the human...
rdcu.be
July 1, 2025 at 1:26 PM
Reposted by Joshua Jacobs
Hi Bluesky! First post here. Kicking things off with a new preprint.

🧠 Using human iEEG + pharmacology, we asked: is hippocampal theta required for retrieval?

Turns out it’s not. Instead, it may reflect a reinstated encoding mode.

Thread below.
www.biorxiv.org/content/10.1...
Cholinergic blockade reveals role for human hippocampal theta in encoding but not retrieval
Cholinergic dysfunction is a hallmark of Alzheimer's disease and other memory disorders. Yet, the neurophysiological mechanisms linking cholinergic signaling to memory remain poorly understood. In thi...
www.biorxiv.org
May 14, 2025 at 2:55 PM
Please come to our Wave Club meeting tomorrow, April 1, at 12pm ET!

Our presenter is Dr. Jon Kleen (UCSF), who will discuss traveling waves in the human hippocampus from microgrids. All are welcome! Register here: forms.gle/5Q4CPqTHAchH...
March 31, 2025 at 9:07 PM
Reposted by Joshua Jacobs
We're thrilled to have Arif Hamid speak next week about spatiotemporal dopamine waves that support reinforcement learning at our online monthly seminar series! Join us on March 4th at 12-1p ET!
@arifahamid.bsky.social
February 24, 2025 at 8:53 PM
Reposted by Joshua Jacobs
We're thrilled to resume our monthly seminar on neural traveling waves in February with Andrea Alamia! Join us on
February 4th at 12-1p ET!
January 21, 2025 at 6:46 PM
Reposted by Joshua Jacobs
Join us tomorrow for this exciting talk! Register for the mailing list or DM us for the zoom link
t.co/cvl42Ma9GG
February 4, 2025 at 2:16 AM