Pinned
Tamara Gedankien
@gedankien.bsky.social
· May 14
Cholinergic blockade reveals role for human hippocampal theta in encoding but not retrieval
Cholinergic dysfunction is a hallmark of Alzheimer's disease and other memory disorders. Yet, the neurophysiological mechanisms linking cholinergic signaling to memory remain poorly understood. In thi...
www.biorxiv.org
Hi Bluesky! First post here. Kicking things off with a new preprint.
🧠 Using human iEEG + pharmacology, we asked: is hippocampal theta required for retrieval?
Turns out it’s not. Instead, it may reflect a reinstated encoding mode.
Thread below.
www.biorxiv.org/content/10.1...
🧠 Using human iEEG + pharmacology, we asked: is hippocampal theta required for retrieval?
Turns out it’s not. Instead, it may reflect a reinstated encoding mode.
Thread below.
www.biorxiv.org/content/10.1...
Reposted by Tamara Gedankien
Excited to share our new paper on theta-phase locking of single neurons during human spatial memory:
www.nature.com/articles/s41...
With @lukaskunz.bsky.social, Joshua Jacobs, and our colleagues from the University of Freiburg
www.nature.com/articles/s41...
With @lukaskunz.bsky.social, Joshua Jacobs, and our colleagues from the University of Freiburg
August 11, 2025 at 4:04 PM
Excited to share our new paper on theta-phase locking of single neurons during human spatial memory:
www.nature.com/articles/s41...
With @lukaskunz.bsky.social, Joshua Jacobs, and our colleagues from the University of Freiburg
www.nature.com/articles/s41...
With @lukaskunz.bsky.social, Joshua Jacobs, and our colleagues from the University of Freiburg
Reposted by Tamara Gedankien
Despite recent criticism from Quiroga to our claim that Concept Neurons emerge from Conjunctive Coding Neurons we claim: “And yet, the hippocampus codes conjunctively!”.
We hope it sparks a smile (and maybe a few debates).
Read here: tinyurl.com/3ycv3vj2
We hope it sparks a smile (and maybe a few debates).
Read here: tinyurl.com/3ycv3vj2
July 2, 2025 at 2:00 PM
Despite recent criticism from Quiroga to our claim that Concept Neurons emerge from Conjunctive Coding Neurons we claim: “And yet, the hippocampus codes conjunctively!”.
We hope it sparks a smile (and maybe a few debates).
Read here: tinyurl.com/3ycv3vj2
We hope it sparks a smile (and maybe a few debates).
Read here: tinyurl.com/3ycv3vj2
Reposted by Tamara Gedankien
🧠 Paper out!
We investigated how hippocampal and cortical ripples support memory during movie watching. We found that:
🎬 Hippocampal ripples mark event boundaries
🧩 Cortical ripples predict later recall
Ripples may help transform real-life experiences into lasting memories!
rdcu.be/eui9l
We investigated how hippocampal and cortical ripples support memory during movie watching. We found that:
🎬 Hippocampal ripples mark event boundaries
🧩 Cortical ripples predict later recall
Ripples may help transform real-life experiences into lasting memories!
rdcu.be/eui9l
Movie-watching evokes ripple-like activity within events and at event boundaries
Nature Communications - The neural processes involved in memory formation for realistic experiences remain poorly understood. Here, the authors found that ripple-like activity in the human...
rdcu.be
July 1, 2025 at 1:26 PM
🧠 Paper out!
We investigated how hippocampal and cortical ripples support memory during movie watching. We found that:
🎬 Hippocampal ripples mark event boundaries
🧩 Cortical ripples predict later recall
Ripples may help transform real-life experiences into lasting memories!
rdcu.be/eui9l
We investigated how hippocampal and cortical ripples support memory during movie watching. We found that:
🎬 Hippocampal ripples mark event boundaries
🧩 Cortical ripples predict later recall
Ripples may help transform real-life experiences into lasting memories!
rdcu.be/eui9l
Reposted by Tamara Gedankien
Cholinergic blockade reveals role for human hippocampal theta in encoding but not retrieval https://www.biorxiv.org/content/10.1101/2025.05.12.653487v1
May 13, 2025 at 8:15 AM
Cholinergic blockade reveals role for human hippocampal theta in encoding but not retrieval https://www.biorxiv.org/content/10.1101/2025.05.12.653487v1
Hi Bluesky! First post here. Kicking things off with a new preprint.
🧠 Using human iEEG + pharmacology, we asked: is hippocampal theta required for retrieval?
Turns out it’s not. Instead, it may reflect a reinstated encoding mode.
Thread below.
www.biorxiv.org/content/10.1...
🧠 Using human iEEG + pharmacology, we asked: is hippocampal theta required for retrieval?
Turns out it’s not. Instead, it may reflect a reinstated encoding mode.
Thread below.
www.biorxiv.org/content/10.1...
Cholinergic blockade reveals role for human hippocampal theta in encoding but not retrieval
Cholinergic dysfunction is a hallmark of Alzheimer's disease and other memory disorders. Yet, the neurophysiological mechanisms linking cholinergic signaling to memory remain poorly understood. In thi...
www.biorxiv.org
May 14, 2025 at 2:55 PM
Hi Bluesky! First post here. Kicking things off with a new preprint.
🧠 Using human iEEG + pharmacology, we asked: is hippocampal theta required for retrieval?
Turns out it’s not. Instead, it may reflect a reinstated encoding mode.
Thread below.
www.biorxiv.org/content/10.1...
🧠 Using human iEEG + pharmacology, we asked: is hippocampal theta required for retrieval?
Turns out it’s not. Instead, it may reflect a reinstated encoding mode.
Thread below.
www.biorxiv.org/content/10.1...