Bryon Silva
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neurogut.bsky.social
Bryon Silva
@neurogut.bsky.social
1.6K followers 5.1K following 15 posts
Decoding how the gut thinks 🦠🪱🧠💪
Neuroscientist with interests in
#EnergyMetabolism #EntericNeurons #Fats
@crick.ac.uk @institutducerveau.bsky.social
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neurogut.bsky.social
Bryon Silva @neurogut.bsky.social · Sep 10
Glia feed neurons upon starvation: our 2022 Nature Metabolism paper revealed a glia-to-neuron ketone body shuttle 💪
#Memories #EnergyMetabolism #Glia @naturemetabolism.bsky.social ky.social

www.nature.com/articles/s42...
neurogut.bsky.social
Oh this is fantastic, peripheral regulation of memory!
October 24, 2025 at 11:30 AM
neurogut.bsky.social
Cool cool cool!
Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway - Nature Neuroscience
Buron et al. show that oxytocin enhances heart rate variability linked to breathing during recovery from stress. This calming and cardio-protective effect is produced through a hypothalamus–brainstem ...
www.nature.com
October 21, 2025 at 7:50 PM
Reposted by Bryon Silva
cagricevrim.bsky.social
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 10, 2025 at 12:50 PM
Reposted by Bryon Silva
flybase.bsky.social
There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase...
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila
FlyBase Update – October 2025 The termination of the NIH/NHGRI FlyBase grant has placed the long-term sustainability of FlyBase at risk. However, thanks to the generous support of several key individuals and institutions, we are pleased to announce that FlyBase will remain operational through the coming year. We extend our deepest gratitude to Yukiko Yamashita, Cassandra Extavour, Hugo Bellen, Thom Kaufman, the Genetics Society of America / Drosophila Board, the Bloomington Drosophila Stock Center, an anonymous donor and the Wellcome Trust. We are especially thankful for a generous gift from Seemay Chou, Jed McCaleb, and The Navigation Fund. We also greatly appreciate the continued support from the broader Drosophila community – your donations and service fees have been vital in helping us stay afloat. Special thanks also go to Jessica Manning for her tireless administrative work at Harvard, to Ruth Lehmann, Hugo Bellen, and Paul Sternberg for advice and efforts, and to the Board of the European Drosophila Society for all their efforts. Sadly, we must also share that several long-standing FlyBase team members have recently moved on. We are immensely grateful to Susan Russo-Gelbart, Lynn Crosby, Gil dos Santos, Kris Broll, Victoria Jenkins, and TyAnna Lovato for their many years of dedicated service and contributions to FlyBase. Looking ahead, ensuring FlyBase’s sustainability beyond the next year – and successfully integrating with the Alliance – will require new funding sources. We kindly ask for your continued support: • European labs: Please consider contributing to the Cambridge, U.K. FlyBase group • U.S. and other non-European labs: Please consider contributing to the U.S. FlyBase groups • Both U.K. and U.S. FlyBase are working diligently to establish an invoicing system. We appreciate your continued patience. For more information on how to support us, please visit: Contribute to FlyBase wiki page https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase
October 3, 2025 at 6:19 PM
Reposted by Bryon Silva
drosostalis.bsky.social
If you find yourself at @edrc2025.bsky.social please check my wonderful postdoc's talk @neurogut.bsky.social at the gut workshop this afternoon. Gut, sex, reproduction, our new story! In combo with @irenemiguel-aliaga.bsky.social! @fly-jedi.bsky.social #EDRC2025
A restricted subset of gut-innervating neurons that express the neuropeptide myosuppressin (Ms) innervate the crop, a stomach-like structure of the fly intestine. This figure shows co-expression between the Ms protein reporter (green) and Ms peptide (red) in the nervous system, and in neuronal projections towards the gut (blue).
September 25, 2025 at 9:20 AM
neurogut.bsky.social
A fantastic way of imaging lipids!
September 15, 2025 at 6:39 PM
neurogut.bsky.social
Dual-cycle CO2 fixation enhances growth and lipid synthesis in Arabidopsis thaliana | Science www.science.org/doi/10.1126/...
Woooooow
Dual-cycle CO2 fixation enhances growth and lipid synthesis in Arabidopsis thaliana
Carbon fixation through the Calvin-Benson-Bassham (CBB) cycle accounts for the majority of carbon dioxide (CO2) uptake from the atmosphere. The CBB cycle generates C3 carbohydrates but is inefficient ...
www.science.org
September 12, 2025 at 9:15 PM
neurogut.bsky.social
Glia feed neurons upon starvation: our 2022 Nature Metabolism paper revealed a glia-to-neuron ketone body shuttle 💪
#Memories #EnergyMetabolism #Glia @naturemetabolism.bsky.social ky.social

www.nature.com/articles/s42...
September 10, 2025 at 9:13 AM
neurogut.bsky.social
This is awesome! Lipid probes for quantitative imaging of lipid transport. A real need in the lipid field!

@nadlerlab.bsky.social
Quantitative imaging of lipid transport in mammalian cells - Nature
Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.
www.nature.com
August 27, 2025 at 11:34 AM
Reposted by Bryon Silva
irenemiguel-aliaga.bsky.social
Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...
March 19, 2025 at 5:31 PM
Reposted by Bryon Silva
cochemelab.bsky.social
🎉Excited to share our latest paper, published in Nature Communications!🎉

"Enhancing autophagy by redox regulation extends lifespan in Drosophila"

#redox #metabolism #ageing #Drosophila

@natcomms.nature.com @mrc-lms.bsky.social

doi.org/10.1038/s414...
Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature Communications
Redox signalling is emerging as an important regulator of metabolism and physiology, which is dysregulated in ageing and disease. Here, the authors show that redox regulation of a key redox sensitive ...
doi.org
June 27, 2025 at 11:21 AM