Cisplatin: "am I a joke to you?"

Extremely grateful to all my co-authors and advisors on this paper, without whom it would not have been possible! (end)

This result adds a key new parameter to the design space for cell delivery technologies (in direct injection, or 3D-printing). Crosslink dynamics matter! (7/8)

It turns out... yes! Cell viabilities were significantly lower for gels with stronger crosslinks (but the same stiffness!) (6/8)

It was then natural to ask, does more sudden yielding affect encapsulated cells as they are being injected? More brittle yielding might introduce heterogeneities in the flow which disrupt cell membranes. (5/8)

We calculated a "yielding speed" which correlated nicely with the crosslink strength. (4/8)

We used techniques to extract data about the speed of the yielding transition from rheological measurements. From these, we could see that the less dynamic materials have a more brittle, or sudden transition, versus a more smooth one. (3/8)

Dynamic hydrogels allow flexible delivery of cells, due to the ability of crosslinks to break and re-form. We analyzed three clinically relevant, dynamic gels with similar stiffness to see how changing crosslink dynamics would change the physics of the yielding transition (2/8)

There is only one lord of the Ring... and he does not share power.

Dakota for America?