Nicolas Bidere
@nbidere.bsky.social
Reposted by Nicolas Bidere
This week #JournalClub #ferroptosis #iron #lysosome @nature.com @institutcurie.bsky.social www.nature.com/articles/s41...
Activation of lysosomal iron triggers ferroptosis in cancer - Nature
Some cancer cells exhibit high loads of reactive iron in lysosomes, and this feature is exploited by using fentomycin-1, a newly developed small molecule, to induce ferroptosis.
www.nature.com
May 26, 2025 at 4:50 PM
Reposted by Nicolas Bidere
👏 Congratulations #YanisMace @nbidere.bsky.social @tiphainedouanne.bsky.social @insermgrandouest.bsky.social
🔍 CYLD cell death and more
🔍 CYLD cell death and more
Happy to share our mini-review on CYLD, its role at the crossroads of life and death decisions, and its regulation through PTMs. @nbidere.bsky.social #YanisMace @labsoap.bsky.social @insermgrandouest.bsky.social
www.frontiersin.org/journals/cel...
www.frontiersin.org/journals/cel...
Frontiers | The good, the bad, and the modified: CYLD’s post-translational tale
www.frontiersin.org
April 9, 2025 at 10:12 AM
👏 Congratulations #YanisMace @nbidere.bsky.social @tiphainedouanne.bsky.social @insermgrandouest.bsky.social
🔍 CYLD cell death and more
🔍 CYLD cell death and more
Reposted by Nicolas Bidere
Important Fact: Higher Education and Research is the place where LGBTI+phobic assaults are most common.
What can we do?
- Continue to stay informed and educated
- Include and make LGBTI+ people visible
- Reject harmful behaviors
Here is our SOAPainbow 🌈
What can we do?
- Continue to stay informed and educated
- Include and make LGBTI+ people visible
- Reject harmful behaviors
Here is our SOAPainbow 🌈
May 12, 2025 at 10:36 AM
Important Fact: Higher Education and Research is the place where LGBTI+phobic assaults are most common.
What can we do?
- Continue to stay informed and educated
- Include and make LGBTI+ people visible
- Reject harmful behaviors
Here is our SOAPainbow 🌈
What can we do?
- Continue to stay informed and educated
- Include and make LGBTI+ people visible
- Reject harmful behaviors
Here is our SOAPainbow 🌈
Reposted by Nicolas Bidere
This #JournalClub @labsoap.bsky.social #Lysosomes #CellDeath #Degradation @science.org @robzonculab.bsky.social www.science.org/doi/10.1126/....
Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins
Breakdown of every transmembrane protein trafficked to lysosomes requires proteolysis of their hydrophobic helical transmembrane domains. Combining lysosomal proteomics with functional genomic dataset...
www.science.org
April 14, 2025 at 1:30 PM
Reposted by Nicolas Bidere
This week @labsoap.bsky.social #JournalClub #bleb #extracellularvesicle @naturecellbiology.bsky.social www.nature.com/articles/s41...
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties - Nature Cell Biology
Jeppesen, Sanchez et al. identify blebbisomes as large membrane-enclosed vesicles containing organelles and secreted by cells. Blebbisomes can both secrete and internalize exosomes and microvesicles.
www.nature.com
March 24, 2025 at 7:42 PM
Reposted by Nicolas Bidere
merci @ouest-france.fr pour la mise à lumière des travaux #recherche #cancer #cerveau #liguecontrelecancer @insermgrandouest.bsky.social @cnrsbiologie.bsky.social @sdcnantes.bsky.social
www.ouest-france.fr/sante/cancer...
www.ouest-france.fr/sante/cancer...
Cancer du cerveau : « On avance », dit la chercheuse nantaise
À l’occasion de la semaine du cerveau, focus sur Julie Gavard, qui encadre une équipe de chercheurs et de thésards qui planchent sur les tumeurs malignes du cerveau de l’adulte.
www.ouest-france.fr
March 15, 2025 at 10:39 AM
merci @ouest-france.fr pour la mise à lumière des travaux #recherche #cancer #cerveau #liguecontrelecancer @insermgrandouest.bsky.social @cnrsbiologie.bsky.social @sdcnantes.bsky.social
www.ouest-france.fr/sante/cancer...
www.ouest-france.fr/sante/cancer...
Reposted by Nicolas Bidere
👀 📝 Words of Advice #co-development #postdocs @febspress.bsky.social @tiphainedouanne.bsky.social @laisbfugio.bsky.social #JaneJardine #QuentinRoux @sararosinska.bsky.social in @labsoap.bsky.social @nbidere.bsky.social @insermgrandouest.bsky.social
febs.onlinelibrary.wiley.com/doi/10.1111/...
febs.onlinelibrary.wiley.com/doi/10.1111/...
FEBS Press
‘Who in their right mind would add another meeting to an already overflowing schedule?’ This thought crossed our minds when we first discussed the idea of a postdoc peer group meeting. We are five ea....
febs.onlinelibrary.wiley.com
March 15, 2025 at 10:36 AM
Reposted by Nicolas Bidere
Our #2025 SOAPbox @labsoap.bsky.social getting ready to celebrate our 10th year anniversary in #nantes 🎁🎂🎊
March 10, 2025 at 7:42 PM
Our #2025 SOAPbox @labsoap.bsky.social getting ready to celebrate our 10th year anniversary in #nantes 🎁🎂🎊
Reposted by Nicolas Bidere
March 9, 2025 at 8:37 PM
Reposted by Nicolas Bidere
L’Inserm est solidaire du mouvement Stand Up For Science
presse.inserm.fr/cest-dans-la...
#StandUpForScience2025
presse.inserm.fr/cest-dans-la...
#StandUpForScience2025
March 6, 2025 at 10:41 AM
L’Inserm est solidaire du mouvement Stand Up For Science
presse.inserm.fr/cest-dans-la...
#StandUpForScience2025
presse.inserm.fr/cest-dans-la...
#StandUpForScience2025
Reposted by Nicolas Bidere
Reposted by Nicolas Bidere
À l’occasion de la Journée internationale des femmes et filles de science, testez vos connaissances sur les femmes scientifiques et l’égalité dans la recherche.
👉 mpdf.cnrs.fr/le-quiz-femm...
#FemmesEnScience #WomenInScience
👉 mpdf.cnrs.fr/le-quiz-femm...
#FemmesEnScience #WomenInScience
February 11, 2025 at 6:13 PM
À l’occasion de la Journée internationale des femmes et filles de science, testez vos connaissances sur les femmes scientifiques et l’égalité dans la recherche.
👉 mpdf.cnrs.fr/le-quiz-femm...
#FemmesEnScience #WomenInScience
👉 mpdf.cnrs.fr/le-quiz-femm...
#FemmesEnScience #WomenInScience
Reposted by Nicolas Bidere
This week #JournalClub @labsoap.bsky.social on #microplastic #bloodbrainbarrier #plastifou in @science.org
www.science.org/doi/10.1126/... 🧠🏭🍃
www.science.org/doi/10.1126/... 🧠🏭🍃
Microplastics in the bloodstream can induce cerebral thrombosis by causing cell obstruction and lead to neurobehavioral abnormalities
Microplastics get in the blood and are eaten by immune cells, leading to cell obstruction and cerebral thrombosis.
www.science.org
January 27, 2025 at 8:53 AM
Reposted by Nicolas Bidere
Thanks to #OTablo initiative #NantesUniversité we could draw @labsoap.bsky.social team recent work on #centriolarsatellites 🖼️🎨🖌️🧑🔬🔬 and its beautiful !
Kudos to all involved 🤗
Kudos to all involved 🤗
January 21, 2025 at 5:18 PM
Thanks to #OTablo initiative #NantesUniversité we could draw @labsoap.bsky.social team recent work on #centriolarsatellites 🖼️🎨🖌️🧑🔬🔬 and its beautiful !
Kudos to all involved 🤗
Kudos to all involved 🤗
Reposted by Nicolas Bidere
please check our recent publication on #EV #extracellularvesicle #breastcancer #lipids @insermgrandouest.bsky.social #JExtracellBio isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
thanks to all involved including our funding agencies
thanks to all involved including our funding agencies
Monitoring concentration and lipid signature of plasma extracellular vesicles from HR+ metastatic breast cancer patients under CDK4/6 inhibitors treatment
Extracellular vesicles (EVs) are cell-derived small membrane structures that transport various molecules. They have emerged as potential circulating biomarkers for monitoring responses to cancer ther...
isevjournals.onlinelibrary.wiley.com
December 17, 2024 at 12:52 PM
please check our recent publication on #EV #extracellularvesicle #breastcancer #lipids @insermgrandouest.bsky.social #JExtracellBio isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
thanks to all involved including our funding agencies
thanks to all involved including our funding agencies
Reposted by Nicolas Bidere
#SOAPosium was a fantastic moment of science food and fun 👩🔬🔬🍭🍪😹😆 - 🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻
December 12, 2024 at 10:03 PM
#SOAPosium was a fantastic moment of science food and fun 👩🔬🔬🍭🍪😹😆 - 🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻
Reposted by Nicolas Bidere
December 4, 2024 at 8:54 PM
Reposted by Nicolas Bidere
@labsoap.bsky.social is proud to announce the 8th SOAPosium on the 12th of December, one more year of SOAP to enjoy together with our guest #VincentSauzeau #InstitutduThorax @insermgrandouest.bsky.social
All we want is teamwork (and chocolate) 🎵
All we want is teamwork (and chocolate) 🎵
December 4, 2024 at 9:52 AM
@labsoap.bsky.social is proud to announce the 8th SOAPosium on the 12th of December, one more year of SOAP to enjoy together with our guest #VincentSauzeau #InstitutduThorax @insermgrandouest.bsky.social
All we want is teamwork (and chocolate) 🎵
All we want is teamwork (and chocolate) 🎵
Reposted by Nicolas Bidere
The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-proteinaceous substrates in vitro https://www.biorxiv.org/content/10.1101/2024.11.29.626046v1
The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-proteinaceous substrates in vitro https://www.biorxiv.org/content/10.1101/2024.11.29.626046v1
HOIL-1 is a RING-between-RING (RBR)-family E3 ubiquitin ligase and component of the linear ubiquitin
www.biorxiv.org
December 1, 2024 at 5:46 AM
The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-proteinaceous substrates in vitro https://www.biorxiv.org/content/10.1101/2024.11.29.626046v1
Reposted by Nicolas Bidere
This week #JournalClub @labsoap.bsky.social #Cancer_Cell
#P53 #STING #BH3mimetics www.cell.com/cancer-cell/...
#P53 #STING #BH3mimetics www.cell.com/cancer-cell/...
Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
Diepstraten et al. demonstrate that p53 enforces apoptosis induced by BH3-mimetic
drugs. To boost BH3-mimetic-induced apoptosis in TP53-mutant blood cancers, STING
agonists were employed to induce pro...
www.cell.com
November 18, 2024 at 2:33 PM
Reposted by Nicolas Bidere
