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natrevgastrohep.nature.com
Nature Reviews Gastroenterology & Hepatology
@natrevgastrohep.nature.com
4.9K followers 1.3K following 650 posts
We publish #gastroenterology & #hepatology Reviews and opinion https://www.nature.com/nrgastro/

#GastroEdPick selections by the Editors: Katrina (@heykatray.bsky.social), Jordan & Eleni

#Gastrosky #LiverSky #Microsky #Medsky
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natrevgastrohep.nature.com
NOVEMBER ISSUE | Our Featured PERSPECTIVE is on "Credible inferences in microbiome research: ensuring rigour, reproducibility and relevance in the era of AI"

www.nature.com/articles/s41...

#Gastrosky #Microsky
Fig. 2: AI-integrated cycle of microbiome research, from hypothesis generation to therapeutic implementation.
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE | PERSPECTIVE "Large language models for clinical decision support in gastroenterology and hepatology"

www.nature.com/articles/s41...

#Gastrosky #Liversky
Fig. 2: Stages of clinical decision making and opportunities for LLM-based decision support.
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE | REVIEW "Parental diet and offspring health: a role for the gut microbiome via epigenetics"

www.nature.com/articles/s41...

#Gastrosky #Microsky
Fig. 3: Epigenetic effects of maternal dietary intake.
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE | REVIEW "Defining the mucosal ecosystem: epithelial–mesenchymal interdependence in gastrointestinal health and disease"

www.nature.com/articles/s41...

#Gastrosky
Fig. 2: Epithelial–stromal remodelling during intestinal regeneration.
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE |JOURNAL CLUB "Diagnosing paediatric coeliac disease"

www.nature.com/articles/s41...

#Gastrosky
"The strength of the AbCD study lies in its rigorous prospective design and multicentre enrolment"
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE | RESEARCH HIGHLIGHT "Aspirin and recurrence of PI3K-mutated CRC"

www.nature.com/articles/s41...

#Gastrosky #Oncsky
Research Highlights: NeuroGASTRO 2025 Maternal gut microbiome in early pregnancy: predictor of preterm birth? Nivolumab and ipilimumab as neoadjuvant therapy for potentially resectable HCC Aspirin and recurrence of PI3K-mutated CRC
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE | RESEARCH HIGHLIGHT "Nivolumab and ipilimumab as neoadjuvant therapy for potentially resectable HCC"

www.nature.com/articles/s41...

#Liversky #Oncsky
Research Highlights: NeuroGASTRO 2025 Maternal gut microbiome in early pregnancy: predictor of preterm birth? Nivolumab and ipilimumab as neoadjuvant therapy for potentially resectable HCC Aspirin and recurrence of PI3K-mutated CRC
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE | RESEARCH HIGHLIGHT "Maternal gut microbiome in early pregnancy: predictor of preterm birth?"

www.nature.com/articles/s41...

#Gastrosky #Microsky
Research Highlights: NeuroGASTRO 2025 Maternal gut microbiome in early pregnancy: predictor of preterm birth? Nivolumab and ipilimumab as neoadjuvant therapy for potentially resectable HCC Aspirin and recurrence of PI3K-mutated CRC
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE | RESEARCH HIGHLIGHT "NeuroGASTRO 2025"

www.nature.com/articles/s41...

#Gastrosky
Research Highlights: NeuroGASTRO 2025 Maternal gut microbiome in early pregnancy: predictor of preterm birth? Nivolumab and ipilimumab as neoadjuvant therapy for potentially resectable HCC Aspirin and recurrence of PI3K-mutated CRC
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE |COMMENT "Food as medicine in gastrointestinal cancer therapy"

www.nature.com/articles/s41...

🍎
Fig. 1: Dietary patterns and components associated with cancer survivorship.
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
NOVEMBER ISSUE |EDITORIAL "Advancing nutrition science for global health"

www.nature.com/articles/s41...

🍎
"Food is medicine, but it is also culture, equity and identity."
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
Our NOVEMBER ISSUE introducing our new Series of articles on NUTRITION is live! Intestinal mucosa, parental diet and offspring health, LLMs and clinical decision, AI and microbiome, and much more!

www.nature.com/nrgastro/vol...
COVER: Artificial intelligence and the gastrointestinal tract, inspired by the Perspective on p788.
October 27, 2025 at 3:42 PM
natrevgastrohep.nature.com
Lots of new content added to our ongoing Series on 'Techniques, technology & analysis', examining cutting-edge techniques and technologies in gastrointestinal and liver research and clinical practice.

Check it out www.nature.com/collections/...
#gastrosky #liversky #endoscopy
screenshot of the introduction and picture for an Article Series on 'Techniques, technology & analysis'. New scientific discoveries and improvements in clinical outcomes are driven by continuously evolving technologies and methodological approaches. In this article series, Nature Reviews Gastroenterology & Hepatology examines the cutting-edge techniques and technologies currently applied in gastrointestinal and liver research and clinical practice, and the approaches that might be available to investigators, clinicians and surgeons in the future.
October 7, 2025 at 8:50 AM
natrevgastrohep.nature.com
OCTOBER ISSUE | PERSPECTIVE "Beyond preservation: future machine perfusion for liver assessment and repair"

www.nature.com/articles/s41...

#Liversky
Fig. 1: Machine design with automated control enables stable and long-term machine perfusion.
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
OCTOBER ISSUE | Our Featured PERSPECTIVE is on "The global burden of inflammatory bowel disease: from 2025 to 2045"

www.nature.com/articles/s41...

#Gastrosky
Fig. 5: A road map to address the rising burden of IBD from 2025 to 2045. IBD, inflammatory bowel disease
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
OCTOBER ISSUE | REVIEW "Dopaminergic signalling in gastrointestinal health and disease"

www.nature.com/articles/s41...

#Gastrosky
Fig. 2: Dopamine and levodopa production in the gut and interaction with the blood–brain barrier.
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
OCTOBER ISSUE | REVIEW "Liver, ageing and disease"

www.nature.com/articles/s41...

#Liversky
Fig. 1: Structural changes in the ageing liver.
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
OCTOBER ISSUE |VIEWPOINT "Next-generation enteric neuroscience — fostering the future of the field"

www.nature.com/articles/s41...

#Gastrosky
"past attendees and organizers of the Little Brain Big Brain meeting discuss their research interests"
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
OCTOBER ISSUE | RESEARCH HIGHLIGHT "AI-assisted colonoscopy and risk of endoscopist deskilling"

www.nature.com/articles/s41...

#Gastrosky
Research highlights: 1. Vaccine for pancreatic and colorectal cancer: phase I AMPLIFY-201 trial 2. Changes in cholera burden across Africa 3. Positive longer-term results for efruxifermin in MASH 4. AI-assisted colonoscopy and risk of endoscopist deskilling MASH, metabolic dysfunction-associated steatohepatitis AI, artificial intelligence
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
OCTOBER ISSUE | RESEARCH HIGHLIGHT "Positive longer-term results for efruxifermin in MASH"

www.nature.com/articles/s41...

#Liversky #Medsky
Research highlights: 1. Vaccine for pancreatic and colorectal cancer: phase I AMPLIFY-201 trial 2. Changes in cholera burden across Africa 3. Positive longer-term results for efruxifermin in MASH 4. AI-assisted colonoscopy and risk of endoscopist deskilling MASH, metabolic dysfunction-associated steatohepatitis AI, artificial intelligence
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
OCTOBER ISSUE | RESEARCH HIGHLIGHT "Changes in cholera burden across Africa"

www.nature.com/articles/s41...

#IDsky #Medsky
Research highlights: 1. Vaccine for pancreatic and colorectal cancer: phase I AMPLIFY-201 trial 2. Changes in cholera burden across Africa 3. Positive longer-term results for efruxifermin in MASH 4. AI-assisted colonoscopy and risk of endoscopist deskilling MASH, metabolic dysfunction-associated steatohepatitis AI, artificial intelligence
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
OCTOBER ISSUE | RESEARCH HIGHLIGHT "Vaccine for pancreatic and colorectal cancer: phase I AMPLIFY-201 trial"

www.nature.com/articles/s41...

#Oncsky #Gastrosky
Research highlights: 1. Vaccine for pancreatic and colorectal cancer: phase I AMPLIFY-201 trial 2. Changes in cholera burden across Africa 3. Positive longer-term results for efruxifermin in MASH 4. AI-assisted colonoscopy and risk of endoscopist deskilling MASH, metabolic dysfunction-associated steatohepatitis AI, artificial intelligence
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
OCTOBER ISSUE |COMMENT "The IDEAL framework for machine perfusion in liver transplantation"

www.nature.com/articles/s41...

#Liversky
Fig. 1: The current IDEAL framework for machine perfusion in liver transplantation. IDEAL, idea, development, exploration, assessment, long-term
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
Our OCTOBER ISSUE is live! Liver and ageing, gastrointestinal dopaminergic signalling, global IBD burden, machine perfusion in liver transplantation, and much more!

www.nature.com/nrgastro/vol...
A landscape of IBD stages, inspired by the Perspective on p708. IBD, inflammatory bowel disease
September 25, 2025 at 7:59 AM
natrevgastrohep.nature.com
SEPTEMBER ISSUE | Our Featured PERSPECTIVE is on "The oesophagus as an immune organ"

www.nature.com/articles/s41...

#Gastrosky
Fig. 2: Immune landscape and barrier regulation in the human oesophageal epithelium.
August 28, 2025 at 8:14 AM