Nathalie M. Grob
@nathalie-grob.bsky.social
Peptide enthusiast and Assistant Professor of Peptide-Based Drug Discovery at ETH Zürich, Switzerland
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Homepage
peptide-discovery.ethz.ch
Are you curious to see what my team and I are up to? Check out our group website here: peptide-discovery.ethz.ch
Reposted by Nathalie M. Grob
🚨 Last week to submit your abstract!
LS2 Annual Meeting 2026:
📍 Zürich | 🗓 Feb 11–12 (YSS: Feb 10)
Join us for keynotes by Sarah-Maria Fendt, Heidi McBride & Jennifer Lippincott-Schwartz + 11 symposia, poster session, & networking.
🔗 Abstracts due Nov 16: annual-meeting.ls2.ch/2026/registr...
LS2 Annual Meeting 2026:
📍 Zürich | 🗓 Feb 11–12 (YSS: Feb 10)
Join us for keynotes by Sarah-Maria Fendt, Heidi McBride & Jennifer Lippincott-Schwartz + 11 symposia, poster session, & networking.
🔗 Abstracts due Nov 16: annual-meeting.ls2.ch/2026/registr...
November 12, 2025 at 3:18 PM
🚨 Last week to submit your abstract!
LS2 Annual Meeting 2026:
📍 Zürich | 🗓 Feb 11–12 (YSS: Feb 10)
Join us for keynotes by Sarah-Maria Fendt, Heidi McBride & Jennifer Lippincott-Schwartz + 11 symposia, poster session, & networking.
🔗 Abstracts due Nov 16: annual-meeting.ls2.ch/2026/registr...
LS2 Annual Meeting 2026:
📍 Zürich | 🗓 Feb 11–12 (YSS: Feb 10)
Join us for keynotes by Sarah-Maria Fendt, Heidi McBride & Jennifer Lippincott-Schwartz + 11 symposia, poster session, & networking.
🔗 Abstracts due Nov 16: annual-meeting.ls2.ch/2026/registr...
Reposted by Nathalie M. Grob
🚨Curious how synthetic fluorophores simplify microscopy? Our review covers applications such as super-resolution microscopy and biosensing. 🎉👩🔬Congrats to my first PhD student, Agnese Nicoli, for the fearless deep dive! 🔬 ⚗️
D-CHAB @ethz.ch
www.nature.com/articles/s41...
D-CHAB @ethz.ch
www.nature.com/articles/s41...
Synthetic fluorophores for live-cell fluorescence microscopy and biosensing - Nature Chemical Biology
Performing live-cell microscopy experiments with high spatial and temporal resolution requires fluorophores with highly optimized properties. This Review examines the progress in developing synthetic ...
www.nature.com
November 5, 2025 at 9:29 PM
🚨Curious how synthetic fluorophores simplify microscopy? Our review covers applications such as super-resolution microscopy and biosensing. 🎉👩🔬Congrats to my first PhD student, Agnese Nicoli, for the fearless deep dive! 🔬 ⚗️
D-CHAB @ethz.ch
www.nature.com/articles/s41...
D-CHAB @ethz.ch
www.nature.com/articles/s41...
Reposted by Nathalie M. Grob
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for genetic code expansion - Nature
Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...
www.nature.com
October 16, 2025 at 2:06 PM
🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...
it all started years ago with a failed experiment
🧵👇 1/9
We are thrilled to share our first preprint on ChemRxiv! Together with @morandilab.bsky.social, we applied nitrogen atom insertion to Trp-containing peptides for late-stage modification. A big thanks to Ann-Sophie, Eva, Masota, and Florin for their outstanding contributions! doi.org/10.26434/che...
Late-Stage Diversification of Native Tryptophan-containing Peptides and Peptide Drugs through Nitrogen Atom Insertion
Peptide drugs are a powerful modality in modern drug dis-covery. Synthetic methods that enable the late-stage diversifi-cation of native peptides through amino acid-specific modifi-cations are thus in...
doi.org
July 3, 2025 at 12:39 PM
We are thrilled to share our first preprint on ChemRxiv! Together with @morandilab.bsky.social, we applied nitrogen atom insertion to Trp-containing peptides for late-stage modification. A big thanks to Ann-Sophie, Eva, Masota, and Florin for their outstanding contributions! doi.org/10.26434/che...
We are hiring! Check out our open PhD position for an exciting industry collaboration with Novo Nordisk:
jobs.ethz.ch/job/view/JOP...
jobs.ethz.ch/job/view/JOP...
PhD Position in Peptide-Based Drug Discovery (Industry Collaboration, w/m/d)
jobs.ethz.ch
June 10, 2025 at 2:30 PM
We are hiring! Check out our open PhD position for an exciting industry collaboration with Novo Nordisk:
jobs.ethz.ch/job/view/JOP...
jobs.ethz.ch/job/view/JOP...
My team and I had a blast at the 2025 Peptide Therapeutics Forum in Basel with inspiring talks from our national and international colleagues and engaging discussions during the poster sessions. Thanks to the @swisschemistry.bsky.social for the generous support! #PTF2025
June 10, 2025 at 9:40 AM
My team and I had a blast at the 2025 Peptide Therapeutics Forum in Basel with inspiring talks from our national and international colleagues and engaging discussions during the poster sessions. Thanks to the @swisschemistry.bsky.social for the generous support! #PTF2025
Only a few more days to register for the 2025 Peptide Therapeutics forum! Join us in Basel on June 05–06 for a firework of peptide chemistry and peptide drug development.
ptf25.scg.ch
ptf25.scg.ch
May 15, 2025 at 7:32 AM
Only a few more days to register for the 2025 Peptide Therapeutics forum! Join us in Basel on June 05–06 for a firework of peptide chemistry and peptide drug development.
ptf25.scg.ch
ptf25.scg.ch
Exciting PhD opportunity at the intersection of machine learning and chemistry!
We are recruiting a PhD student in machine learning for photocatalysis! In this project, we will collaborate with the group of Frank Glorius @gloriusgroup.bsky.social to develop predictive tools for energy-transfer-catalyzed photocycloadditions.
Reposts appreciated!
jobs.ethz.ch/job/view/JOP...
Reposts appreciated!
jobs.ethz.ch/job/view/JOP...
PhD position in machine learning for photocatalysis
jobs.ethz.ch
May 13, 2025 at 2:39 PM
Exciting PhD opportunity at the intersection of machine learning and chemistry!
Reposted by Nathalie M. Grob
Peptide Therapeutics Forum 2025 - Last Chance to submit your abstract for a talk!
@biozentrum.unibas.ch
‼️Submit your abstract today via ptf25.scg.ch/registration
#ptf25 #scs #medchem #switzerland #symposia
@biozentrum.unibas.ch
‼️Submit your abstract today via ptf25.scg.ch/registration
#ptf25 #scs #medchem #switzerland #symposia
April 28, 2025 at 6:20 AM
Peptide Therapeutics Forum 2025 - Last Chance to submit your abstract for a talk!
@biozentrum.unibas.ch
‼️Submit your abstract today via ptf25.scg.ch/registration
#ptf25 #scs #medchem #switzerland #symposia
@biozentrum.unibas.ch
‼️Submit your abstract today via ptf25.scg.ch/registration
#ptf25 #scs #medchem #switzerland #symposia
Today I had the pleasure of hosting @ninahartrampf.bsky.social as a speaker in the Seminars on Drug Discovery and Development. Thank you for a fantastic talk and inspiring conversations with the members of our institute!
February 26, 2025 at 8:24 PM
Today I had the pleasure of hosting @ninahartrampf.bsky.social as a speaker in the Seminars on Drug Discovery and Development. Thank you for a fantastic talk and inspiring conversations with the members of our institute!
Do you want to know more about peptide-based drug discovery and the mission of my research team at ETH? Check out the article on our department’s website:
chab.ethz.ch/en/news-and-...
chab.ethz.ch/en/news-and-...
Peptide-based drugs without borders
Peptides act as signal mediators in the body and are on the rise as therapeutic agents. However, their full potential can often be limited by rapid degradation and elimination. Nathalie Grob, the new ...
chab.ethz.ch
February 13, 2025 at 12:58 PM
Do you want to know more about peptide-based drug discovery and the mission of my research team at ETH? Check out the article on our department’s website:
chab.ethz.ch/en/news-and-...
chab.ethz.ch/en/news-and-...
Reposted by Nathalie M. Grob
Our Synthesis Tag (SynTag) for the synthesis of aggregating peptides and proteins is now published in JACS 🥳 Congratulations to first authors Héloïse & Elyse and everyone else involved ✨✨
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
A Versatile “Synthesis Tag” (SynTag) for the Chemical Synthesis of Aggregating Peptides and Proteins
Solid-phase peptide synthesis (SPPS) and native chemical ligation (NCL) are powerful methods for obtaining peptides and proteins that are otherwise inaccessible. Nonetheless, numerous sequences are di...
pubs.acs.org
December 6, 2024 at 6:39 AM
Our Synthesis Tag (SynTag) for the synthesis of aggregating peptides and proteins is now published in JACS 🥳 Congratulations to first authors Héloïse & Elyse and everyone else involved ✨✨
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by Nathalie M. Grob
What better first post than to advertise this position. Come join our group!
Our group is recruiting a postdoctoral researcher for a project on reactive machine learning potentials. Reposts and spreading the word to interested people in your network appreciated!
jobs.ethz.ch/job/view/JOP...
Our group is recruiting a postdoctoral researcher for a project on reactive machine learning potentials. Reposts and spreading the word to interested people in your network appreciated!
jobs.ethz.ch/job/view/JOP...
Postdoc position in reactive machine learning potentials
jobs.ethz.ch
November 21, 2024 at 12:43 PM
What better first post than to advertise this position. Come join our group!
Our group is recruiting a postdoctoral researcher for a project on reactive machine learning potentials. Reposts and spreading the word to interested people in your network appreciated!
jobs.ethz.ch/job/view/JOP...
Our group is recruiting a postdoctoral researcher for a project on reactive machine learning potentials. Reposts and spreading the word to interested people in your network appreciated!
jobs.ethz.ch/job/view/JOP...
Happy to see my Medicinal Chemistry and Chemical Biology Highlight out in the current CHIMIA and online. Thank you to @klanglab.bsky.social for the invitation!
www.chimia.ch/chimia/artic...
www.chimia.ch/chimia/artic...
A New Era for Peptide Therapeutics: Innovations, Challenges, and Future Directions: Medicinal Chemistry and Chemical Biology Highlights
| CHIMIA
www.chimia.ch
November 29, 2024 at 12:39 PM
Happy to see my Medicinal Chemistry and Chemical Biology Highlight out in the current CHIMIA and online. Thank you to @klanglab.bsky.social for the invitation!
www.chimia.ch/chimia/artic...
www.chimia.ch/chimia/artic...
Are you curious to see what my team and I are up to? Check out our group website here: peptide-discovery.ethz.ch
Homepage
peptide-discovery.ethz.ch
November 21, 2024 at 2:28 PM
Are you curious to see what my team and I are up to? Check out our group website here: peptide-discovery.ethz.ch