Nature Biomedical Engineering
@natbiomedeng.nature.com
A scientific journal publishing cutting-edge advances at the intersection of the life and physical sciences. Posts by the editors.
We at Nature Biomedical Engineering sincerely wish you all a wonderful holiday season! We are enjoying a much-needed break and looking forward to a wonderful 2026!
December 24, 2025 at 2:40 PM
We at Nature Biomedical Engineering sincerely wish you all a wonderful holiday season! We are enjoying a much-needed break and looking forward to a wonderful 2026!
We are thrilled to share our December issue, which features our editorial covering some of our favorite papers from 2025! www.nature.com/articles/s41...
December 16, 2025 at 10:24 PM
We are thrilled to share our December issue, which features our editorial covering some of our favorite papers from 2025! www.nature.com/articles/s41...
From Lie and Zhu -- Nonexpansive biodegradable matrix promotes blood vessel organoid development for neurovascular repair and functional recovery in ischaemic stroke
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 27, 2025 at 3:31 PM
From Lie and Zhu -- Nonexpansive biodegradable matrix promotes blood vessel organoid development for neurovascular repair and functional recovery in ischaemic stroke
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A computational method designs receptors called T-SenSERs, which have predictable signalling responses to tumour microenvironment soluble factors and can be co-expressed with conventional CARs in T cells to enhance their therapeutic activity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 4, 2025 at 1:04 AM
A computational method designs receptors called T-SenSERs, which have predictable signalling responses to tumour microenvironment soluble factors and can be co-expressed with conventional CARs in T cells to enhance their therapeutic activity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Hybrid gRNAs significantly increase targeted editing in the liver while simultaneously reducing unwanted bystander editing in humanized mouse models.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 4, 2025 at 1:03 AM
Hybrid gRNAs significantly increase targeted editing in the liver while simultaneously reducing unwanted bystander editing in humanized mouse models.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A recombinant adeno-associated virus system for restricted gene expression in brain endothelial cells enables cerebrovascular disease modelling.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 4, 2025 at 1:01 AM
A recombinant adeno-associated virus system for restricted gene expression in brain endothelial cells enables cerebrovascular disease modelling.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Kidney organoids derived from human pluripotent stem cells are infused in a normothermic machine perfusion system to condition explanted porcine kidneys, and the feasibility and viability of their in vivo engraftment are demonstrated. www.nature.com/articles/s41...
November 4, 2025 at 12:56 AM
Kidney organoids derived from human pluripotent stem cells are infused in a normothermic machine perfusion system to condition explanted porcine kidneys, and the feasibility and viability of their in vivo engraftment are demonstrated. www.nature.com/articles/s41...
Amazing organoids! Thoracic vertebral segment-specific spinal cord organoids transplanted in a spinal cord injury mouse model can precisely match the transplantation site, establish synaptic connections, enhance neuroelectric conduction and restore motor function. www.nature.com/articles/s41...
October 24, 2025 at 11:15 PM
Amazing organoids! Thoracic vertebral segment-specific spinal cord organoids transplanted in a spinal cord injury mouse model can precisely match the transplantation site, establish synaptic connections, enhance neuroelectric conduction and restore motor function. www.nature.com/articles/s41...
Please check out our October issue which went live today! www.nature.com/natbiomedeng...
October 17, 2025 at 6:41 PM
Please check out our October issue which went live today! www.nature.com/natbiomedeng...
The deep generative model PepMimic achieves sequence and structure co-design of all-atom peptide binders conditioned on a protein target and another known binder. www.nature.com/articles/s41...
October 1, 2025 at 7:49 PM
The deep generative model PepMimic achieves sequence and structure co-design of all-atom peptide binders conditioned on a protein target and another known binder. www.nature.com/articles/s41...
We really hope the field benefits from this comparative study. A comprehensive benchmarking of 19 histopathology foundation models finds that a vision-language foundation model outperforms vision-only models. www.nature.com/articles/s41...
October 1, 2025 at 7:48 PM
We really hope the field benefits from this comparative study. A comprehensive benchmarking of 19 histopathology foundation models finds that a vision-language foundation model outperforms vision-only models. www.nature.com/articles/s41...
CAR-T cells engineered with αPD-L1–IL-12 fusion proteins show antitumour activity in mouse models of prostate and ovarian cancer. www.nature.com/articles/s41...
October 1, 2025 at 7:47 PM
CAR-T cells engineered with αPD-L1–IL-12 fusion proteins show antitumour activity in mouse models of prostate and ovarian cancer. www.nature.com/articles/s41...
A brain–heart–eye axis is generated through integration of multi-omics and multi-organ data from UKBB, BLSA, FinnGen and PGC, revealing phenotypic landscapes and genetic arcitectures of disease. www.nature.com/articles/s41...
October 1, 2025 at 7:46 PM
A brain–heart–eye axis is generated through integration of multi-omics and multi-organ data from UKBB, BLSA, FinnGen and PGC, revealing phenotypic landscapes and genetic arcitectures of disease. www.nature.com/articles/s41...
A modularized open-source pipeline for invasive brain signal decoding bridges the gap between closed-loop neuromodulation and clinical brain–computer interface approaches in a large patient cohort. www.nature.com/articles/s41...
October 1, 2025 at 7:43 PM
A modularized open-source pipeline for invasive brain signal decoding bridges the gap between closed-loop neuromodulation and clinical brain–computer interface approaches in a large patient cohort. www.nature.com/articles/s41...
How cool is this paper! Artificial cilia array devices are developed for sound frequency decoding and executing tasks such as drug release. www.nature.com/articles/s41...
October 1, 2025 at 7:42 PM
How cool is this paper! Artificial cilia array devices are developed for sound frequency decoding and executing tasks such as drug release. www.nature.com/articles/s41...
A paper out today shows that monocytes derived from bone marrow leucocytes chemically conjugated with a Tau-specific aptamer enable systemic delivery across the blood–brain barrier and targeted clearance of extracellular Tau in Alzheimer’s disease mouse models. www.nature.com/articles/s41...
October 1, 2025 at 1:50 PM
A paper out today shows that monocytes derived from bone marrow leucocytes chemically conjugated with a Tau-specific aptamer enable systemic delivery across the blood–brain barrier and targeted clearance of extracellular Tau in Alzheimer’s disease mouse models. www.nature.com/articles/s41...
Please check out our new paper on Advanced Sensing of Aggregates—Parkinson’s Disease, an imaging method to generate large-scale α-synuclein aggregate maps in post-mortem human brain tissue. www.nature.com/articles/s41...
October 1, 2025 at 1:47 PM
Please check out our new paper on Advanced Sensing of Aggregates—Parkinson’s Disease, an imaging method to generate large-scale α-synuclein aggregate maps in post-mortem human brain tissue. www.nature.com/articles/s41...
One of many cool papers out today in nBME! A nanoparticle-based microfluidic assay enables rapid sterility testing of biopharmaceuticals. www.nature.com/articles/s41...
October 1, 2025 at 1:45 PM
One of many cool papers out today in nBME! A nanoparticle-based microfluidic assay enables rapid sterility testing of biopharmaceuticals. www.nature.com/articles/s41...
Nature Biomedical Engineering is hiring! We are open to scientists will all relevant expertise, but we will prioritize applicants with experience in machine learning. Deadline is Oct 20. Please RT! springernature.wd3.myworkdayjobs.com/SpringerNatu...
September 30, 2025 at 7:14 PM
Nature Biomedical Engineering is hiring! We are open to scientists will all relevant expertise, but we will prioritize applicants with experience in machine learning. Deadline is Oct 20. Please RT! springernature.wd3.myworkdayjobs.com/SpringerNatu...