Nancy Choudhary
@nancy-choudhary.bsky.social
PhD student at IZMB, University of Bonn
Interested in Plant specialized metabolism, evolutionary biology and genomics
Interested in Plant specialized metabolism, evolutionary biology and genomics
Pinned
Have you ever wondered why pumpkins are never purple or blue like other plants? 🎃🌈
While most plants can produce pink, blue, and purple pigments (thanks to anthocyanins), the Cucurbitaceae family 🍈 🍉 🥒have lost all the pathway genes to produce these pigments.
🔗 doi.org/10.1101/2025...
While most plants can produce pink, blue, and purple pigments (thanks to anthocyanins), the Cucurbitaceae family 🍈 🍉 🥒have lost all the pathway genes to produce these pigments.
🔗 doi.org/10.1101/2025...
Reposted by Nancy Choudhary
We are looking for undergrads to visit us over the next summer!
If you study in the UK, USA, or Canada, you might be eligible for the DAAD-RISE program 🇩🇪🧬
Learn more 👉 www.izmb.uni-bonn.de/en/pbb/news#DR
Do excellent science in Bonn next summer!
@puckerlab.bsky.social @unibonn.bsky.social
If you study in the UK, USA, or Canada, you might be eligible for the DAAD-RISE program 🇩🇪🧬
Learn more 👉 www.izmb.uni-bonn.de/en/pbb/news#DR
Do excellent science in Bonn next summer!
@puckerlab.bsky.social @unibonn.bsky.social
November 18, 2025 at 10:35 AM
We are looking for undergrads to visit us over the next summer!
If you study in the UK, USA, or Canada, you might be eligible for the DAAD-RISE program 🇩🇪🧬
Learn more 👉 www.izmb.uni-bonn.de/en/pbb/news#DR
Do excellent science in Bonn next summer!
@puckerlab.bsky.social @unibonn.bsky.social
If you study in the UK, USA, or Canada, you might be eligible for the DAAD-RISE program 🇩🇪🧬
Learn more 👉 www.izmb.uni-bonn.de/en/pbb/news#DR
Do excellent science in Bonn next summer!
@puckerlab.bsky.social @unibonn.bsky.social
Reposted by Nancy Choudhary
Yesterday, Nancy shared her Cucurbitaceae anthocyanin loss story with colleagues at our institute. Comprehensive talk highlighting the most striking discoveries. Please find the full story here:
doi.org/10.1101/2025...
#PlantSci #Evolution
doi.org/10.1101/2025...
#PlantSci #Evolution
November 5, 2025 at 6:05 AM
Yesterday, Nancy shared her Cucurbitaceae anthocyanin loss story with colleagues at our institute. Comprehensive talk highlighting the most striking discoveries. Please find the full story here:
doi.org/10.1101/2025...
#PlantSci #Evolution
doi.org/10.1101/2025...
#PlantSci #Evolution
Reposted by Nancy Choudhary
🎃 Why are (Halloween) pumpkins orange – and not pink or blue? This secret is explored by @bpucker.bsky.social, @nancy-choudhary.bsky.social and Marie Hagedorn. Their research examines how carotenoids took over, making Jack O’Lanterns forever orange: www.uni-bonn.de/en/news/colo.... Happy Halloween!
October 31, 2025 at 1:07 PM
🎃 Why are (Halloween) pumpkins orange – and not pink or blue? This secret is explored by @bpucker.bsky.social, @nancy-choudhary.bsky.social and Marie Hagedorn. Their research examines how carotenoids took over, making Jack O’Lanterns forever orange: www.uni-bonn.de/en/news/colo.... Happy Halloween!
Reposted by Nancy Choudhary
We are looking for curious undergrads to join our research team next summer!
If you study in the UK, USA, or Canada, you might be eligible for the DAAD-RISE program 🇩🇪🧬
Learn more 👉 www.izmb.uni-bonn.de/en/pbb/news#DR
Come do science in Bonn next summer!
@puckerlab.bsky.social @unibonn.bsky.social
If you study in the UK, USA, or Canada, you might be eligible for the DAAD-RISE program 🇩🇪🧬
Learn more 👉 www.izmb.uni-bonn.de/en/pbb/news#DR
Come do science in Bonn next summer!
@puckerlab.bsky.social @unibonn.bsky.social
October 26, 2025 at 8:44 AM
We are looking for curious undergrads to join our research team next summer!
If you study in the UK, USA, or Canada, you might be eligible for the DAAD-RISE program 🇩🇪🧬
Learn more 👉 www.izmb.uni-bonn.de/en/pbb/news#DR
Come do science in Bonn next summer!
@puckerlab.bsky.social @unibonn.bsky.social
If you study in the UK, USA, or Canada, you might be eligible for the DAAD-RISE program 🇩🇪🧬
Learn more 👉 www.izmb.uni-bonn.de/en/pbb/news#DR
Come do science in Bonn next summer!
@puckerlab.bsky.social @unibonn.bsky.social
Reposted by Nancy Choudhary
New preprint from the group:
🧬 Large-scale Phylogenomics Reveals Systematic Loss of Anthocyanin Biosynthesis Genes at the Family Level in Cucurbitaceae
👉 doi.org/10.1101/2025...
@nancy-choudhary.bsky.social @bpucker.bsky.social
🧬 Large-scale Phylogenomics Reveals Systematic Loss of Anthocyanin Biosynthesis Genes at the Family Level in Cucurbitaceae
👉 doi.org/10.1101/2025...
@nancy-choudhary.bsky.social @bpucker.bsky.social
October 11, 2025 at 2:29 PM
New preprint from the group:
🧬 Large-scale Phylogenomics Reveals Systematic Loss of Anthocyanin Biosynthesis Genes at the Family Level in Cucurbitaceae
👉 doi.org/10.1101/2025...
@nancy-choudhary.bsky.social @bpucker.bsky.social
🧬 Large-scale Phylogenomics Reveals Systematic Loss of Anthocyanin Biosynthesis Genes at the Family Level in Cucurbitaceae
👉 doi.org/10.1101/2025...
@nancy-choudhary.bsky.social @bpucker.bsky.social
Have you ever wondered why pumpkins are never purple or blue like other plants? 🎃🌈
While most plants can produce pink, blue, and purple pigments (thanks to anthocyanins), the Cucurbitaceae family 🍈 🍉 🥒have lost all the pathway genes to produce these pigments.
🔗 doi.org/10.1101/2025...
While most plants can produce pink, blue, and purple pigments (thanks to anthocyanins), the Cucurbitaceae family 🍈 🍉 🥒have lost all the pathway genes to produce these pigments.
🔗 doi.org/10.1101/2025...
October 10, 2025 at 11:35 AM
Have you ever wondered why pumpkins are never purple or blue like other plants? 🎃🌈
While most plants can produce pink, blue, and purple pigments (thanks to anthocyanins), the Cucurbitaceae family 🍈 🍉 🥒have lost all the pathway genes to produce these pigments.
🔗 doi.org/10.1101/2025...
While most plants can produce pink, blue, and purple pigments (thanks to anthocyanins), the Cucurbitaceae family 🍈 🍉 🥒have lost all the pathway genes to produce these pigments.
🔗 doi.org/10.1101/2025...
Reposted by Nancy Choudhary
Excited to share our new preprint!
🧬 Large-scale Phylogenomics Reveals Systematic Loss of Anthocyanin Biosynthesis Genes at the Family Level in Cucurbitaceae
👉 doi.org/10.1101/2025...
A deep dive into the genomic evolution of color in cucurbits 🎃🍉 — feedback welcome!
@puckerlab.bsky.social
🧬 Large-scale Phylogenomics Reveals Systematic Loss of Anthocyanin Biosynthesis Genes at the Family Level in Cucurbitaceae
👉 doi.org/10.1101/2025...
A deep dive into the genomic evolution of color in cucurbits 🎃🍉 — feedback welcome!
@puckerlab.bsky.social
October 9, 2025 at 4:47 AM
Excited to share our new preprint!
🧬 Large-scale Phylogenomics Reveals Systematic Loss of Anthocyanin Biosynthesis Genes at the Family Level in Cucurbitaceae
👉 doi.org/10.1101/2025...
A deep dive into the genomic evolution of color in cucurbits 🎃🍉 — feedback welcome!
@puckerlab.bsky.social
🧬 Large-scale Phylogenomics Reveals Systematic Loss of Anthocyanin Biosynthesis Genes at the Family Level in Cucurbitaceae
👉 doi.org/10.1101/2025...
A deep dive into the genomic evolution of color in cucurbits 🎃🍉 — feedback welcome!
@puckerlab.bsky.social
Reposted by Nancy Choudhary
"Evolutionary Rewiring of Anthocyanin Biosynthesis Pathway in Poaceae" 🎨
We describe how grasses have reorganized the anthocyanin biosynthesis pathway through gene loss, regulatory shifts, and independent evolution:
🔗 doi.org/10.1101/2025...
@bpucker.bsky.social @nancy-choudhary.bsky.social
We describe how grasses have reorganized the anthocyanin biosynthesis pathway through gene loss, regulatory shifts, and independent evolution:
🔗 doi.org/10.1101/2025...
@bpucker.bsky.social @nancy-choudhary.bsky.social
Evolutionary Rewiring of Anthocyanin Biosynthesis Pathway in Poaceae
Poaceae is a species-rich family of plants in the monocots harboring many important crop species. As grasses, these plants lack striking flowers that are typically pigmented by anthocyanins. Here, we ...
doi.org
September 23, 2025 at 8:15 AM
"Evolutionary Rewiring of Anthocyanin Biosynthesis Pathway in Poaceae" 🎨
We describe how grasses have reorganized the anthocyanin biosynthesis pathway through gene loss, regulatory shifts, and independent evolution:
🔗 doi.org/10.1101/2025...
@bpucker.bsky.social @nancy-choudhary.bsky.social
We describe how grasses have reorganized the anthocyanin biosynthesis pathway through gene loss, regulatory shifts, and independent evolution:
🔗 doi.org/10.1101/2025...
@bpucker.bsky.social @nancy-choudhary.bsky.social
Reposted by Nancy Choudhary
Evolutionary Rewiring of Anthocyanin Biosynthesis Pathway in Poaceae www.biorxiv.org/content/10.1...
Evolutionary Rewiring of Anthocyanin Biosynthesis Pathway in Poaceae
Poaceae is a species-rich family of plants in the monocots harboring many important crop species. As grasses, these plants lack striking flowers that are typically pigmented by anthocyanins. Here, we ...
www.biorxiv.org
September 22, 2025 at 1:05 AM
Evolutionary Rewiring of Anthocyanin Biosynthesis Pathway in Poaceae www.biorxiv.org/content/10.1...
If you're new to plant genomics research, don't miss the supplementary hands-on manual we included - it walks you through the major data analysis steps in a typical plant genomics project! ☘️ 🧬
#PlantScience #GenomeAssembly #OpenScience
#PlantScience #GenomeAssembly #OpenScience
🚀 Exciting update: "Cookbook for Plant Genome Sequences" now includes an updated overview figure! 🌱🔬
Check out how to run a plant genome sequencing project:
www.preprints.org/manuscript/2...
#Genomics #LongReads #Bioinformatics
@puckerlab.bsky.social
Check out how to run a plant genome sequencing project:
www.preprints.org/manuscript/2...
#Genomics #LongReads #Bioinformatics
@puckerlab.bsky.social
September 16, 2025 at 1:52 PM
If you're new to plant genomics research, don't miss the supplementary hands-on manual we included - it walks you through the major data analysis steps in a typical plant genomics project! ☘️ 🧬
#PlantScience #GenomeAssembly #OpenScience
#PlantScience #GenomeAssembly #OpenScience
Reposted by Nancy Choudhary
Thinking of starting a plant genome sequencing project?
Check out this step-by-step guide:
Cookbook for Plant Genome Sequences
📖 www.preprints.org/manuscript/2...
#Genomics #Bioinformatics #LongReads
@puckerlab.bsky.social
Check out this step-by-step guide:
Cookbook for Plant Genome Sequences
📖 www.preprints.org/manuscript/2...
#Genomics #Bioinformatics #LongReads
@puckerlab.bsky.social
www.preprints.org
August 22, 2025 at 5:08 AM
Thinking of starting a plant genome sequencing project?
Check out this step-by-step guide:
Cookbook for Plant Genome Sequences
📖 www.preprints.org/manuscript/2...
#Genomics #Bioinformatics #LongReads
@puckerlab.bsky.social
Check out this step-by-step guide:
Cookbook for Plant Genome Sequences
📖 www.preprints.org/manuscript/2...
#Genomics #Bioinformatics #LongReads
@puckerlab.bsky.social
Reposted by Nancy Choudhary
KIPEs3: Automatic annotation of biosynthesis pathways
doi.org/10.1371/jour...
#PlantSci #Bioinformatics #Genomics #DataScience #AI
doi.org/10.1371/jour...
#PlantSci #Bioinformatics #Genomics #DataScience #AI
KIPEs3: Automatic annotation of biosynthesis pathways
Flavonoids and carotenoids are pigments involved in stress mitigation and numerous other processes. Both pigment classes can contribute to flower and fruit coloration. Flavonoid aglycones and caroteno...
doi.org
July 26, 2025 at 6:28 PM
KIPEs3: Automatic annotation of biosynthesis pathways
doi.org/10.1371/jour...
#PlantSci #Bioinformatics #Genomics #DataScience #AI
doi.org/10.1371/jour...
#PlantSci #Bioinformatics #Genomics #DataScience #AI
Reposted by Nancy Choudhary
Conserved amino acid residues and gene expression patterns associated with the substrate preferences of the competing enzymes FLS and DFR
doi.org/10.1371/jour...
#Metabolism #PlantSci #GeneExpression #Flavonoids #Flavonols #Anthocyanins #Evolution #Bioinformatics #BigData
doi.org/10.1371/jour...
#Metabolism #PlantSci #GeneExpression #Flavonoids #Flavonols #Anthocyanins #Evolution #Bioinformatics #BigData
Conserved amino acid residues and gene expression patterns associated with the substrate preferences of the competing enzymes FLS and DFR
Background Flavonoids, an important class of specialized metabolites, are synthesized from phenylalanine and present in almost all plant species. Different branches of flavonoid biosynthesis lead to p...
doi.org
July 26, 2025 at 9:12 PM
Conserved amino acid residues and gene expression patterns associated with the substrate preferences of the competing enzymes FLS and DFR
doi.org/10.1371/jour...
#Metabolism #PlantSci #GeneExpression #Flavonoids #Flavonols #Anthocyanins #Evolution #Bioinformatics #BigData
doi.org/10.1371/jour...
#Metabolism #PlantSci #GeneExpression #Flavonoids #Flavonols #Anthocyanins #Evolution #Bioinformatics #BigData
Reposted by Nancy Choudhary
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
doi.org/10.1038/s414...
#Genomics #Withanolides #SpecializedMetabolism #BiosyntheticGeneCluster #LongReadSequencing #MetabolicEngineering #OpenAccess #OpenData
doi.org/10.1038/s414...
#Genomics #Withanolides #SpecializedMetabolism #BiosyntheticGeneCluster #LongReadSequencing #MetabolicEngineering #OpenAccess #OpenData
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis - Nature Communications
Withanolides are plant steroids with potent bioactivities found in many medicinal plants including Withania somnifera, but their biosynthetic pathway is largely unknown. Here, the authors report the g...
doi.org
July 26, 2025 at 10:34 PM
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
doi.org/10.1038/s414...
#Genomics #Withanolides #SpecializedMetabolism #BiosyntheticGeneCluster #LongReadSequencing #MetabolicEngineering #OpenAccess #OpenData
doi.org/10.1038/s414...
#Genomics #Withanolides #SpecializedMetabolism #BiosyntheticGeneCluster #LongReadSequencing #MetabolicEngineering #OpenAccess #OpenData
Reposted by Nancy Choudhary
ICYMI: We explored the biosynthesis of withanolides 🧪
Here’s the official press release by @unihannover.bsky.social & @unibonn.bsky.social:
🔗 www.uni-bonn.de/en/news/130-...
📄 Original research: doi.org/10.1038/s414...
#Science #NaturalProducts
@frankelab.bsky.social @puckerlab.bsky.social
Here’s the official press release by @unihannover.bsky.social & @unibonn.bsky.social:
🔗 www.uni-bonn.de/en/news/130-...
📄 Original research: doi.org/10.1038/s414...
#Science #NaturalProducts
@frankelab.bsky.social @puckerlab.bsky.social
July 19, 2025 at 4:46 AM
ICYMI: We explored the biosynthesis of withanolides 🧪
Here’s the official press release by @unihannover.bsky.social & @unibonn.bsky.social:
🔗 www.uni-bonn.de/en/news/130-...
📄 Original research: doi.org/10.1038/s414...
#Science #NaturalProducts
@frankelab.bsky.social @puckerlab.bsky.social
Here’s the official press release by @unihannover.bsky.social & @unibonn.bsky.social:
🔗 www.uni-bonn.de/en/news/130-...
📄 Original research: doi.org/10.1038/s414...
#Science #NaturalProducts
@frankelab.bsky.social @puckerlab.bsky.social
Reposted by Nancy Choudhary
Withanolide #biosynthesis from nightshade plants decoded. Withanolide steroids are used as a basis for medications for centuries.
Now published by a team around @frankelab.bsky.social + @puckerlab.bsky.social in @natcomms.nature.com (DOI: 10.1038/s41467-025-61686-1).
Now published by a team around @frankelab.bsky.social + @puckerlab.bsky.social in @natcomms.nature.com (DOI: 10.1038/s41467-025-61686-1).
July 14, 2025 at 4:35 PM
Withanolide #biosynthesis from nightshade plants decoded. Withanolide steroids are used as a basis for medications for centuries.
Now published by a team around @frankelab.bsky.social + @puckerlab.bsky.social in @natcomms.nature.com (DOI: 10.1038/s41467-025-61686-1).
Now published by a team around @frankelab.bsky.social + @puckerlab.bsky.social in @natcomms.nature.com (DOI: 10.1038/s41467-025-61686-1).