Nael Nadif Kasri
@naelnadifkasri-lab.bsky.social
Neurobiologist interested in synaptic communication, neuronal networks, neurodevelopmental disorders, stem cell models and much more | Professor Group leader Radboudumc | http://www.nadifkasri-lab.com/Home.html
-Patient-derived organoids from individuals with Koolen-de Vries syndrome reveal impaired DNA replication and reduced synapse formation, driven by excess R-loops.
August 30, 2025 at 7:37 AM
-Patient-derived organoids from individuals with Koolen-de Vries syndrome reveal impaired DNA replication and reduced synapse formation, driven by excess R-loops.
Key insights:
-The NSL complex prevents R-loop accumulation at weakly transcribed promoters, safeguarding DNA replication.
-Loss of NSL disrupts S-phase progression and causes replication stress.
-The NSL complex prevents R-loop accumulation at weakly transcribed promoters, safeguarding DNA replication.
-Loss of NSL disrupts S-phase progression and causes replication stress.
August 30, 2025 at 7:37 AM
Key insights:
-The NSL complex prevents R-loop accumulation at weakly transcribed promoters, safeguarding DNA replication.
-Loss of NSL disrupts S-phase progression and causes replication stress.
-The NSL complex prevents R-loop accumulation at weakly transcribed promoters, safeguarding DNA replication.
-Loss of NSL disrupts S-phase progression and causes replication stress.
It was a pleasure of having @cedricboeckx.bsky.social visiting us on his way to the Max Planck in Nijmegen. He even wanted to help @ellylewerissa.bsky.social in the lab. Look at her reaction.
July 2, 2025 at 4:59 PM
It was a pleasure of having @cedricboeckx.bsky.social visiting us on his way to the Max Planck in Nijmegen. He even wanted to help @ellylewerissa.bsky.social in the lab. Look at her reaction.
Deeply honoured to receive this grant from the Coalition to Cure CHD2 to advance our work on CHD2-related disorders.
Together with my outstanding PhD student, @ellylewerissa.bsky.social , we’re excited to embark on this project
Together with my outstanding PhD student, @ellylewerissa.bsky.social , we’re excited to embark on this project
June 27, 2025 at 6:20 AM
Deeply honoured to receive this grant from the Coalition to Cure CHD2 to advance our work on CHD2-related disorders.
Together with my outstanding PhD student, @ellylewerissa.bsky.social , we’re excited to embark on this project
Together with my outstanding PhD student, @ellylewerissa.bsky.social , we’re excited to embark on this project
Wishing everyone a lovely holiday season.
Warm MEA- Xmas greetings from the lab!
Warm MEA- Xmas greetings from the lab!
December 20, 2024 at 5:03 PM
Wishing everyone a lovely holiday season.
Warm MEA- Xmas greetings from the lab!
Warm MEA- Xmas greetings from the lab!
