Nabina Pun
@nabinapun.bsky.social
Postdoctoral Researcher @witherslab.bsky.social at University of Oxford | Immuno-oncology
Reposted by Nabina Pun
This study was fantastically led by @NabinaPun98 working together with @UCytlak. Nabina did an amazing job leading the charge into a new area for our lab and is now at the start of what is going to be a truly fantastic career in research, watch this space for more to come!
October 29, 2025 at 5:23 PM
This study was fantastically led by @NabinaPun98 working together with @UCytlak. Nabina did an amazing job leading the charge into a new area for our lab and is now at the start of what is going to be a truly fantastic career in research, watch this space for more to come!
🙏 Huge thanks to all my co-authors and collaborators - this was a truly team effort!
Grateful for the support of the Dyer, Illidge and Travis lab and everyone in RadNet who helped make this project possible. @cruk-mi.bsky.social
#Immunology #Radiobiology #Monocytes #TissueRepair #Research #Science
Grateful for the support of the Dyer, Illidge and Travis lab and everyone in RadNet who helped make this project possible. @cruk-mi.bsky.social
#Immunology #Radiobiology #Monocytes #TissueRepair #Research #Science
October 29, 2025 at 5:51 PM
🙏 Huge thanks to all my co-authors and collaborators - this was a truly team effort!
Grateful for the support of the Dyer, Illidge and Travis lab and everyone in RadNet who helped make this project possible. @cruk-mi.bsky.social
#Immunology #Radiobiology #Monocytes #TissueRepair #Research #Science
Grateful for the support of the Dyer, Illidge and Travis lab and everyone in RadNet who helped make this project possible. @cruk-mi.bsky.social
#Immunology #Radiobiology #Monocytes #TissueRepair #Research #Science
💡 Big picture:
Immune cell recruitment isn’t always harmful.
Here, CCR2⁺ monocytes actually protect against injury by supporting IL-17 production and maintaining the intestinal barrier after radiation.
Immune cell recruitment isn’t always harmful.
Here, CCR2⁺ monocytes actually protect against injury by supporting IL-17 production and maintaining the intestinal barrier after radiation.
October 29, 2025 at 5:51 PM
💡 Big picture:
Immune cell recruitment isn’t always harmful.
Here, CCR2⁺ monocytes actually protect against injury by supporting IL-17 production and maintaining the intestinal barrier after radiation.
Immune cell recruitment isn’t always harmful.
Here, CCR2⁺ monocytes actually protect against injury by supporting IL-17 production and maintaining the intestinal barrier after radiation.
🔍 Why it matters:
Radiotherapy saves lives, but gut toxicity often limits how much treatment patients can tolerate.
By revealing how monocytes and ILC3s cooperate to protect intestinal tissue, we identify new therapeutic opportunities to reduce side effects and improve outcomes.
Radiotherapy saves lives, but gut toxicity often limits how much treatment patients can tolerate.
By revealing how monocytes and ILC3s cooperate to protect intestinal tissue, we identify new therapeutic opportunities to reduce side effects and improve outcomes.
October 29, 2025 at 5:51 PM
🔍 Why it matters:
Radiotherapy saves lives, but gut toxicity often limits how much treatment patients can tolerate.
By revealing how monocytes and ILC3s cooperate to protect intestinal tissue, we identify new therapeutic opportunities to reduce side effects and improve outcomes.
Radiotherapy saves lives, but gut toxicity often limits how much treatment patients can tolerate.
By revealing how monocytes and ILC3s cooperate to protect intestinal tissue, we identify new therapeutic opportunities to reduce side effects and improve outcomes.
🧬 What we found:
Abdominal/pelvic radiotherapy can damage healthy intestinal tissue - a major challenge in cancer care.
We discovered a protective immune pathway:
CCR2 → monocyte recruitment → ILC3 → IL-17 → barrier protection
This axis helps the gut resist radiation-induced injury.
Abdominal/pelvic radiotherapy can damage healthy intestinal tissue - a major challenge in cancer care.
We discovered a protective immune pathway:
CCR2 → monocyte recruitment → ILC3 → IL-17 → barrier protection
This axis helps the gut resist radiation-induced injury.
October 29, 2025 at 5:51 PM
🧬 What we found:
Abdominal/pelvic radiotherapy can damage healthy intestinal tissue - a major challenge in cancer care.
We discovered a protective immune pathway:
CCR2 → monocyte recruitment → ILC3 → IL-17 → barrier protection
This axis helps the gut resist radiation-induced injury.
Abdominal/pelvic radiotherapy can damage healthy intestinal tissue - a major challenge in cancer care.
We discovered a protective immune pathway:
CCR2 → monocyte recruitment → ILC3 → IL-17 → barrier protection
This axis helps the gut resist radiation-induced injury.