Masataka Yanagawa
myanagawa.bsky.social
Masataka Yanagawa
@myanagawa.bsky.social
Associate Prof., Tohoku Univ. Single-molecule biophysics, Pharmacology, GPCR, RTK, TRP, Signaling
Congratulations to Ritsuki and thanks to all collaborators and our teams! Your combined expertise in MD simulations, biochemistry, cell-based assays, and single-molecule imaging made these GPCR signaling discoveries possible.
August 6, 2025 at 2:07 PM
Check out our three-color single-molecule time-lapse imaging! We simultaneously track V2R, β-arrestin, and PIP2 probe dynamics before and after ligand stimulation in real-time. Watch these molecules co-accumulate into immobile membrane domains upon receptor activation!
August 6, 2025 at 2:07 PM
This video is the original data from Yoda et al. 2024 BPPB.
”Four-color single-molecule imaging system for tracking GPCR dynamics with fluorescent HiBiT peptide" #Biophysics
doi.org/10.2142/biop...
Four-color single-molecule imaging system for tracking GPCR dynamics with fluorescent HiBiT peptide
Single-molecule imaging provides information on diffusion dynamics, oligomerization, and protein-protein interactions in living cells. To simultaneous …
doi.org
January 11, 2025 at 12:39 PM