Mychael Lourenco
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mvlourenco.bsky.social
Mychael Lourenco
@mvlourenco.bsky.social
870 followers 680 following 21 posts
Neuroscientist studying molecular mechanisms of Alzheimer’s disease and related disorders. Assistant Professor at UFRJ, Brazil.
www.lourencolab.org
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Reposted by Mychael Lourenco
labwaggoner.bsky.social
Aging activates escape of the silent X chromosome in the female mouse hippocampus
www.science.org/doi/10.1126/...
Aging activates escape of the silent X chromosome in the female mouse hippocampus
Aging activates the silent X chromosome, increasing escape expression, and potentially cognitive resilience, in the female mouse.
www.science.org
March 5, 2025 at 8:15 PM
mvlourenco.bsky.social
You can also read the original paper here:
elifesciences.org/articles/99862
Dysfunctional S1P/S1PR1 signaling in the dentate gyrus drives vulnerability of chronic pain-related memory impairment
RNA-Seq analysis and molecular biological approaches reveal a novel mechanism and provide a promising preventive and therapeutic molecular target for vulnerability to chronic pain-related memory impai...
elifesciences.org
January 27, 2025 at 8:44 PM
mvlourenco.bsky.social
We had essential collaborations with D'Or Institute (Brazil) and @elizabethhead.bsky.social @ucirvine.bsky.social and very much appreciate the important funding by NIH, @serrapilheira.org and Alzheimer's Association.
January 9, 2025 at 5:06 PM
mvlourenco.bsky.social
Plasma carnitine also associate with Aβ and tau accumulation and further improved AD classification when combined with CSF Aβ and tau. Check it out if you're interested! #ENDALZ
January 9, 2025 at 5:06 PM