Matthew Seetin
mseetin.bsky.social
Matthew Seetin
@mseetin.bsky.social
Bioinformatics Scientist at PacBio
Reposted by Matthew Seetin
#PacBio announces major upcoming advances for #Revio and #Vega designed to lower genome costs, expand multiomic capabilities, and support regulated research.

The SPRQ-Nx chemistry, now in beta access, delivers complete genomes for under $300 at scale.

View the press release: bit.ly/4o06eyH
October 14, 2025 at 3:33 PM
Reposted by Matthew Seetin
Just in: #PacBio HiFi long-read sequencing is powering the National Institute on Aging’s Long Life Family Study.

Up to 7,800 genomes and epigenomes will be sequenced on Revio systems to uncover rare variants, methylation patterns, and other factors linked to healthy aging.

🔗 bit.ly/3IUDdFo
October 8, 2025 at 3:02 PM
Reposted by Matthew Seetin
One concern I've heard for long-read #metagenomic sequencing is the amount of DNA needed.

New Ampli-Fi protocol from #PacBio now allows as little as 1ng input for library prep - that's kind of a game changer for low biomass samples.
Unlock new possibilities in #genomics with the #PacBio Ampli-Fi protocol! Sequence ultra-limited samples, like insects and preserved specimens, with as little as 1 ng DNA. Explore how this innovation is reshaping #HiFisequencing for diverse species. 🌿🦥

Blog here: bit.ly/3Cidm6R

#PAG32
New Ampli-Fi ultra-low-input protocol will support HiFi sequencing from as little as 1 ng of DNA - PacBio
The Ampli-Fi protocol is a new workflow that will enable HiFi sequencing from as little as 1 ng of genomic DNA.
bit.ly
January 13, 2025 at 7:40 PM
Reposted by Matthew Seetin
“StarPhase: Comprehensive Phase-Aware Pharmacogenomic Diplotyper for Long-Read Sequencing Data” is now on biorxiv! In this work, we explore the use of long-read sequencing (#PacBio #HiFi) for #pharmacogenomics #PGx. 1/N

Pre-print: doi.org/10.1101/2024...
Repo: github.com/PacificBiosc...
GitHub - PacificBiosciences/pb-StarPhase: A phase-aware pharmacogenomic diplotyper for PacBio datasets
A phase-aware pharmacogenomic diplotyper for PacBio datasets - PacificBiosciences/pb-StarPhase
github.com
December 11, 2024 at 2:30 PM
Reposted by Matthew Seetin
A bright new day for plant and animal #genomics is here! Join #PacBio at PAG 2025 in San Diego to explore the power of #HiFisequencing. Visit our booth, attend our workshop, or schedule a one-on-one meeting.

Details here: bit.ly/41hR9Qw

#PAG32
December 11, 2024 at 4:27 PM
Reposted by Matthew Seetin

If you were interested but missed it: www.pacb.com/wp-content/u...
www.pacb.com
November 13, 2024 at 7:00 PM
Reposted by Matthew Seetin
A little birdie told us we should migrate to bluer skies. 😉 Hello Bluesky world. 👋🌎 Please re-share this post so we can follow you and help to grow the genomics community on here! 🧬✨
November 12, 2024 at 4:15 PM