mschlack.bsky.social
@mschlack.bsky.social
The point is not to eliminate discussion of diversity, but diversity itself. Let's revise history, airbrush out all the non-white and female people who made important contributions. Then we can say, see, we don't need those other "people."

Witness trolling Amy Cony Barrett as a "DEI hire."
March 7, 2025 at 8:07 PM
Further update: 538 has been killed off by Disney. Was it just an economic decision or is this another corporate de-controversy move? I hope there will be some reporting on that.
www.theguardian.com/us-news/2025...
Political poll news site 538 to close amid larger shuttering across ABC and Disney
Disney is reportedly cutting staff across ABC News Group and its entertainment network as media layoffs continue
www.theguardian.com
March 6, 2025 at 12:08 AM
Update: it's now buried within the site at projects.fivethirtyeight.com/polls/. And sure enough, Trump is now 0.3% net DISAPPROVAL. Fishy that it's now off the homepage.
Latest Polls
The latest political polls and polling averages from FiveThirtyEight.
projects.fivethirtyeight.com
March 5, 2025 at 9:29 PM
I like the old Chinese saying (allegedly): Even a broken clock is right twice a day.
March 5, 2025 at 7:31 PM
I have seen a number of articles like this one in recent years, all of which suggest that the basic science behind the amyloid hypothesis is flawed. Instead of funding for trials of flawed drugs, maybe fund more basic research in other directions?
pmc.ncbi.nlm.nih.gov/articles/PMC...
Failure of current Alzheimer’s disease hypotheses
pmc.ncbi.nlm.nih.gov
February 27, 2025 at 9:42 PM
But as yet there are no drugs that prevent amyloid plaque formation, correct? And that the drugs under trial may slow symptomatic progression but cannot remove enough plaque to stop or reverse the disease?
February 27, 2025 at 8:56 PM
Well, I'd agree, in the sense no other theory better explains the disease. But results increasingly suggest that amyloid tangles are a symptom with a deeper cause. Treating the tangles so far only brings limited, in depth and time, relief. That doesn't confirm the hypothesis, either. You disagree?
February 27, 2025 at 5:36 PM
My understanding is that there is increasing skepticism about the amyloid hypothesis among biologists. While tangled amyloid clearly accompanies Alzheimers and may cause some of its symptoms, it remains elusive what causes the amyloid tangles (or tau, or alpha synuclein in Parkinsons). Not so?
February 27, 2025 at 5:32 PM
No, that was another failed drug, intepirdine. And that drug worked differently than leqembi. But it seems that investors pray on the desperation of Alzheimer patients' relatives to help push drugs through approvals even though they have very low efficacy and dangerous side effects.
February 26, 2025 at 7:56 PM