Moritz Mall
@moritzmall.bsky.social
Research group leader @German Cancer Research Center, reconstructing human development and disease using cell fate engineering
🎉 Herzlichen Dank für den @gscnoffice.bsky.social-Preis „Publication of the Year 2025“ zu unserer @natgenet.nature.com Publikation: www.nature.com/articles/s41...
Diese Auszeichnung ist echte Teamleistung—danke an alle Mitwirkenden. Auf zu den nächsten Schritten im Kampf gegen Krebs!
Diese Auszeichnung ist echte Teamleistung—danke an alle Mitwirkenden. Auf zu den nächsten Schritten im Kampf gegen Krebs!
August 22, 2025 at 4:26 PM
🎉 Herzlichen Dank für den @gscnoffice.bsky.social-Preis „Publication of the Year 2025“ zu unserer @natgenet.nature.com Publikation: www.nature.com/articles/s41...
Diese Auszeichnung ist echte Teamleistung—danke an alle Mitwirkenden. Auf zu den nächsten Schritten im Kampf gegen Krebs!
Diese Auszeichnung ist echte Teamleistung—danke an alle Mitwirkenden. Auf zu den nächsten Schritten im Kampf gegen Krebs!
🚨 @dkfz.bsky.social Postdoctoral Fellowships 2025 — Postdoc opening (Mall Lab)
Work at the interface of neurodevelopment, epigenetic repression & cancer neuroscience.
Apply: jobs.dkfz.de/en/jobs/1679...
#Postdoc #Plasticity #Neurodegeneration #CancerNeuroscience
Work at the interface of neurodevelopment, epigenetic repression & cancer neuroscience.
Apply: jobs.dkfz.de/en/jobs/1679...
#Postdoc #Plasticity #Neurodegeneration #CancerNeuroscience
August 21, 2025 at 2:34 PM
🚨 @dkfz.bsky.social Postdoctoral Fellowships 2025 — Postdoc opening (Mall Lab)
Work at the interface of neurodevelopment, epigenetic repression & cancer neuroscience.
Apply: jobs.dkfz.de/en/jobs/1679...
#Postdoc #Plasticity #Neurodegeneration #CancerNeuroscience
Work at the interface of neurodevelopment, epigenetic repression & cancer neuroscience.
Apply: jobs.dkfz.de/en/jobs/1679...
#Postdoc #Plasticity #Neurodegeneration #CancerNeuroscience
Hands down the best meeting this year so far! Thanks for the fantastic organization @matlupien.bsky.social @shenhui1986.bsky.social Bonus was a musical finale - who said science cannot be fun :)
May 25, 2025 at 12:36 PM
Hands down the best meeting this year so far! Thanks for the fantastic organization @matlupien.bsky.social @shenhui1986.bsky.social Bonus was a musical finale - who said science cannot be fun :)
What keeps cancer cells in check—and can we tame them? In 2 collaborative preprints, we trace glioblastoma cell transitions in space and decode what regulates their plasticity 🧠👇
📍 Spatial & multi-omic atlas: www.biorxiv.org/content/10.1...
📍 Regulatory logic: www.biorxiv.org/content/10.1...
📍 Spatial & multi-omic atlas: www.biorxiv.org/content/10.1...
📍 Regulatory logic: www.biorxiv.org/content/10.1...
May 16, 2025 at 3:57 PM
What keeps cancer cells in check—and can we tame them? In 2 collaborative preprints, we trace glioblastoma cell transitions in space and decode what regulates their plasticity 🧠👇
📍 Spatial & multi-omic atlas: www.biorxiv.org/content/10.1...
📍 Regulatory logic: www.biorxiv.org/content/10.1...
📍 Spatial & multi-omic atlas: www.biorxiv.org/content/10.1...
📍 Regulatory logic: www.biorxiv.org/content/10.1...
Movement for prevention, nature for inspiration 🌿🌍
Today's @dkfz.bsky.social Lunch Walk took us to the Botanical Garden—a perfect match for #EarthWeek and our goal to promote #CancerPrevention through regular activity. Thanks to all who joined!
#DKFZgeht #HealthyWorkplace #Heidelberg
Today's @dkfz.bsky.social Lunch Walk took us to the Botanical Garden—a perfect match for #EarthWeek and our goal to promote #CancerPrevention through regular activity. Thanks to all who joined!
#DKFZgeht #HealthyWorkplace #Heidelberg
April 25, 2025 at 11:22 AM
Movement for prevention, nature for inspiration 🌿🌍
Today's @dkfz.bsky.social Lunch Walk took us to the Botanical Garden—a perfect match for #EarthWeek and our goal to promote #CancerPrevention through regular activity. Thanks to all who joined!
#DKFZgeht #HealthyWorkplace #Heidelberg
Today's @dkfz.bsky.social Lunch Walk took us to the Botanical Garden—a perfect match for #EarthWeek and our goal to promote #CancerPrevention through regular activity. Thanks to all who joined!
#DKFZgeht #HealthyWorkplace #Heidelberg
🚨 Postdoc position open!
Join our organoid engineering team in Heidelberg to advance disease modeling & drug testing in cancer & brain disorders using AI, single-cell tech & assembloids.
🧠 5 yrs funding (CZS)
🌐 Apply: bit.ly/heidelberg-o...
#Postdoc #Organoids #Neuroscience
Join our organoid engineering team in Heidelberg to advance disease modeling & drug testing in cancer & brain disorders using AI, single-cell tech & assembloids.
🧠 5 yrs funding (CZS)
🌐 Apply: bit.ly/heidelberg-o...
#Postdoc #Organoids #Neuroscience
April 16, 2025 at 2:29 PM
🚨 Postdoc position open!
Join our organoid engineering team in Heidelberg to advance disease modeling & drug testing in cancer & brain disorders using AI, single-cell tech & assembloids.
🧠 5 yrs funding (CZS)
🌐 Apply: bit.ly/heidelberg-o...
#Postdoc #Organoids #Neuroscience
Join our organoid engineering team in Heidelberg to advance disease modeling & drug testing in cancer & brain disorders using AI, single-cell tech & assembloids.
🧠 5 yrs funding (CZS)
🌐 Apply: bit.ly/heidelberg-o...
#Postdoc #Organoids #Neuroscience
Want to decode #cancer & #autism with organoids, stem cells & genomics?
We’re hiring PhD students @dkfz.bsky.social via the fully funded International PhD Program!
🌍 Heidelberg
🔗 www.dkfz.de/en/career/in...
#PhDopportunity #CancerNeuroscience #Genomics
We’re hiring PhD students @dkfz.bsky.social via the fully funded International PhD Program!
🌍 Heidelberg
🔗 www.dkfz.de/en/career/in...
#PhDopportunity #CancerNeuroscience #Genomics
April 15, 2025 at 9:48 AM
Want to decode #cancer & #autism with organoids, stem cells & genomics?
We’re hiring PhD students @dkfz.bsky.social via the fully funded International PhD Program!
🌍 Heidelberg
🔗 www.dkfz.de/en/career/in...
#PhDopportunity #CancerNeuroscience #Genomics
We’re hiring PhD students @dkfz.bsky.social via the fully funded International PhD Program!
🌍 Heidelberg
🔗 www.dkfz.de/en/career/in...
#PhDopportunity #CancerNeuroscience #Genomics
Join us on April 4 at 11:00 for a @dkfz.bsky.social Distinguished Lecture by Filipe Pereira from
@lunduniversity-med.bsky.social: "In Vivo Dendritic Cell Reprogramming for Cancer Immunotherapy" 📍DKFZ Lecture Hall, Heidelberg. Filipe is pioneering #cellreprogramming to evolve #cancer #immunotherapy.
@lunduniversity-med.bsky.social: "In Vivo Dendritic Cell Reprogramming for Cancer Immunotherapy" 📍DKFZ Lecture Hall, Heidelberg. Filipe is pioneering #cellreprogramming to evolve #cancer #immunotherapy.
March 31, 2025 at 2:04 PM
Join us on April 4 at 11:00 for a @dkfz.bsky.social Distinguished Lecture by Filipe Pereira from
@lunduniversity-med.bsky.social: "In Vivo Dendritic Cell Reprogramming for Cancer Immunotherapy" 📍DKFZ Lecture Hall, Heidelberg. Filipe is pioneering #cellreprogramming to evolve #cancer #immunotherapy.
@lunduniversity-med.bsky.social: "In Vivo Dendritic Cell Reprogramming for Cancer Immunotherapy" 📍DKFZ Lecture Hall, Heidelberg. Filipe is pioneering #cellreprogramming to evolve #cancer #immunotherapy.
Deadline Approaching (Mar 15)! @dkfz.bsky.social Clinician-Scientist Fellowships open for applications—study #autism & brain/liver #cancer by exploring cell fate plasticity. 2-year contract with protected research time.
Apply now: www.dkfz.de/clinicianscientist
#CancerResearch #Neuroscience #Autism
Apply now: www.dkfz.de/clinicianscientist
#CancerResearch #Neuroscience #Autism
March 11, 2025 at 12:08 PM
Deadline Approaching (Mar 15)! @dkfz.bsky.social Clinician-Scientist Fellowships open for applications—study #autism & brain/liver #cancer by exploring cell fate plasticity. 2-year contract with protected research time.
Apply now: www.dkfz.de/clinicianscientist
#CancerResearch #Neuroscience #Autism
Apply now: www.dkfz.de/clinicianscientist
#CancerResearch #Neuroscience #Autism
Big congrats to @karowlab.bsky.social for this well-deserved promotion! I can even share a more authentic picture capturing this fantastic moment. Keep on rocking the world of cell fate reprogramming and stem cell-based disease modeling!
February 21, 2025 at 4:45 PM
Big congrats to @karowlab.bsky.social for this well-deserved promotion! I can even share a more authentic picture capturing this fantastic moment. Keep on rocking the world of cell fate reprogramming and stem cell-based disease modeling!
If you enjoyed our @naturegenet.bsky.social paper on how PROX1 safeguards hepatocyte identity, check out the behind-the-scenes Research Briefing—both free to read:
Paper: rdcu.be/d9IFg
Briefing: rdcu.be/eaLYL
#CellPlasticity #CancerResearch
Paper: rdcu.be/d9IFg
Briefing: rdcu.be/eaLYL
#CellPlasticity #CancerResearch
February 21, 2025 at 1:23 PM
If you enjoyed our @naturegenet.bsky.social paper on how PROX1 safeguards hepatocyte identity, check out the behind-the-scenes Research Briefing—both free to read:
Paper: rdcu.be/d9IFg
Briefing: rdcu.be/eaLYL
#CellPlasticity #CancerResearch
Paper: rdcu.be/d9IFg
Briefing: rdcu.be/eaLYL
#CellPlasticity #CancerResearch
Only 1 week left to register for the International Heidelberg Organoid Meeting (iHOME) 2025, March 20–21!
Don’t miss the keynote by @kimbakjensen.bsky.social (ReNEW Copenhagen) on guiding intestinal stem cell fate in health & disease. Register now: indico.dkfz.de/event/1249/ #Organoids #StemCells
Don’t miss the keynote by @kimbakjensen.bsky.social (ReNEW Copenhagen) on guiding intestinal stem cell fate in health & disease. Register now: indico.dkfz.de/event/1249/ #Organoids #StemCells
February 21, 2025 at 10:22 AM
Only 1 week left to register for the International Heidelberg Organoid Meeting (iHOME) 2025, March 20–21!
Don’t miss the keynote by @kimbakjensen.bsky.social (ReNEW Copenhagen) on guiding intestinal stem cell fate in health & disease. Register now: indico.dkfz.de/event/1249/ #Organoids #StemCells
Don’t miss the keynote by @kimbakjensen.bsky.social (ReNEW Copenhagen) on guiding intestinal stem cell fate in health & disease. Register now: indico.dkfz.de/event/1249/ #Organoids #StemCells
Don’t miss #iHOME2025 on March 20–21 in Heidelberg! Keynote speaker Dr. Joep Beumer (Institute of Human Biology, Basel) will share how advanced #organoid engineering reveals intestinal cell states and functions. Register for this and more by Feb 28: indico.dkfz.de/event/1249/
#Organoids #Conference
#Organoids #Conference
February 20, 2025 at 12:47 PM
Don’t miss #iHOME2025 on March 20–21 in Heidelberg! Keynote speaker Dr. Joep Beumer (Institute of Human Biology, Basel) will share how advanced #organoid engineering reveals intestinal cell states and functions. Register for this and more by Feb 28: indico.dkfz.de/event/1249/
#Organoids #Conference
#Organoids #Conference
Thrilled to announce another #iHOME2025 (Mar 20–21) keynote: Maximilian Reichert @tum.de discussing “Mapping Tumor Cell States in Pancreatic Cancer with Advanced Organoid Technology.” Hear how organoid approaches reveal key cancer plasticity mechanisms! Register here: indico.dkfz.de/event/1249/
February 19, 2025 at 12:11 PM
Thrilled to announce another #iHOME2025 (Mar 20–21) keynote: Maximilian Reichert @tum.de discussing “Mapping Tumor Cell States in Pancreatic Cancer with Advanced Organoid Technology.” Hear how organoid approaches reveal key cancer plasticity mechanisms! Register here: indico.dkfz.de/event/1249/
Join iHOME 2025 (Mar 20–21 in Heidelberg) for cutting-edge organoid research spanning basic to clinical science! One of many highlights is the keynote speaker, Barbara Treutlein, ETH Zurich, discussing using single-cell tech to map organoid development. Register by Feb 28: indico.dkfz.de/event/1249/
February 18, 2025 at 12:01 PM
Join iHOME 2025 (Mar 20–21 in Heidelberg) for cutting-edge organoid research spanning basic to clinical science! One of many highlights is the keynote speaker, Barbara Treutlein, ETH Zurich, discussing using single-cell tech to map organoid development. Register by Feb 28: indico.dkfz.de/event/1249/
Huge thanks to our #collaborators, colleagues & funding partners for supporting the work: #HITBR @ERC_Research @dfg_public @DKFZ @zi_mannheim. Special thanks to our teams @DKFZ @EMBL @UniBasel_en @zauggj, esp. @ecyrblim & @AryanKamal_ for leading the way! rdcu.be/d9IFg
February 13, 2025 at 12:16 PM
Huge thanks to our #collaborators, colleagues & funding partners for supporting the work: #HITBR @ERC_Research @dfg_public @DKFZ @zi_mannheim. Special thanks to our teams @DKFZ @EMBL @UniBasel_en @zauggj, esp. @ecyrblim & @AryanKamal_ for leading the way! rdcu.be/d9IFg
Our findings show that active repression preserves cell identity. PROX1 is just one example—uncovering more #SafeguardRepressors could reshape regenerative medicine & cancer therapy. Stay tuned for what’s next! 🚀 #CancerTherapy #StemCells www.embopress.org/doi/full/10....
February 13, 2025 at 12:16 PM
Our findings show that active repression preserves cell identity. PROX1 is just one example—uncovering more #SafeguardRepressors could reshape regenerative medicine & cancer therapy. Stay tuned for what’s next! 🚀 #CancerTherapy #StemCells www.embopress.org/doi/full/10....
Beyond #cancer, PROX1 enhances hepatocyte #reprogramming, repressing alternate fate regulators & aiding liver #regeneration after injury. This highlights how active repression supports cancer prevention & tissue #repair. #RegenerativeMedicine #Reprogramming
February 13, 2025 at 12:16 PM
Beyond #cancer, PROX1 enhances hepatocyte #reprogramming, repressing alternate fate regulators & aiding liver #regeneration after injury. This highlights how active repression supports cancer prevention & tissue #repair. #RegenerativeMedicine #Reprogramming
Manipulating #PROX1 switched mouse liver tumors between #hepatocellularcarcinoma and #cholangiocarcinoma states, nearly doubling survival in both. This underscores a new principle: actively stopping unwanted plasticity is crucial to #prevent disease.
February 13, 2025 at 12:16 PM
Manipulating #PROX1 switched mouse liver tumors between #hepatocellularcarcinoma and #cholangiocarcinoma states, nearly doubling survival in both. This underscores a new principle: actively stopping unwanted plasticity is crucial to #prevent disease.
We screened 1,296 transcription factors in 18 cell types to predict #Safeguards—#Repressors that silence plasticity. PROX1 emerged as key for hepatocytes, shutting down alternate fates & preventing #LiverCancer. Check your favorite TF here apps.embl.de/safeguard/ #GeneRegulation
February 13, 2025 at 12:16 PM
We screened 1,296 transcription factors in 18 cell types to predict #Safeguards—#Repressors that silence plasticity. PROX1 emerged as key for hepatocytes, shutting down alternate fates & preventing #LiverCancer. Check your favorite TF here apps.embl.de/safeguard/ #GeneRegulation
#CellPlasticity—the ability of cells to change their identity—is vital for tissue growth and repair. But when it goes unchecked, it can fuel #cancer. Our latest study examines how to block #LiverCancer by actively suppressing plasticity. www.nature.com/articles/s41... #CancerBiology
February 13, 2025 at 12:16 PM
#CellPlasticity—the ability of cells to change their identity—is vital for tissue growth and repair. But when it goes unchecked, it can fuel #cancer. Our latest study examines how to block #LiverCancer by actively suppressing plasticity. www.nature.com/articles/s41... #CancerBiology