Molecular Microbiology, University of Sheffield
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molmicrosheffield.bsky.social
Molecular Microbiology, University of Sheffield
@molmicrosheffield.bsky.social
430 followers 870 following 10 posts
A multi-disciplinary research cluster studying the machinery of microbial life - from their fine molecular structure to interactions with their hosts and the environment.

https://www.sheffield.ac.uk/biosciences/research/areas/molecular-microbiology
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Reposted by Molecular Microbiology, University of Sheffield
robfagan.bsky.social
1. Characterising the role of the dual-function VanT in C. difficile vancomycin resistance.
A collaboration between our group in @molmicrosheffield.bsky.social and the groups of @gavinhthomas.bsky.social and Marjan van der Woude at the University of York

www.findaphd.com/phds/project...
A simplified version of Figure 4 from our paper https://doi.org/10.1371/journal.pbio.3002741 describing the evolution of vancomycin resistance in C. difficile. The shows phase contract and fluorescence microscopy images of a wild type and a vancomycin resistant C. difficile. In the fluorescence channel can be seen vancomycin -bodipy binding to the mid-cells of wild type cells but this labelling is absent in the resistant bacteria
October 31, 2025 at 3:44 PM
Reposted by Molecular Microbiology, University of Sheffield
perbullough.bsky.social
Beautiful CryoEM work by our University of Sheffield colleagues @molmicrosheffield.bsky.social

Structural basis of multitasking by the apicoplast DNA polymerase from Plasmodium falciparum url: academic.oup.com/nar/article/...
Structural basis of multitasking by the apicoplast DNA polymerase from Plasmodium falciparum
Abstract. Plasmodium falciparum is a eukaryotic pathogen responsible for the majority of malaria-related fatalities. Plasmodium belongs to the phylum Apico
academic.oup.com
October 17, 2025 at 9:53 AM
molmicrosheffield.bsky.social
Our four 3rd year PhD students all gave great presentations at our School of Biosciences symposium. Thanks to @helenkmatthews.bsky.social for being an excellent chair
September 25, 2025 at 11:28 AM
Reposted by Molecular Microbiology, University of Sheffield
iandealidbury.bsky.social
Our latest paper on the identification of a key GBT demethylase present in aerobic environmental bacteria. Multi-domain enzyme linking methionine synthesis and osmolyte consumption. @michiamausz.bsky.social @molmicrosheffield.bsky.social @warwicklifesci.bsky.social www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
September 16, 2025 at 6:20 PM
Reposted by Molecular Microbiology, University of Sheffield
microsos.bsky.social
We are happy to announce 2 more keynote speakers for #PMS2025!

We’re excited to welcome:

🔬 @gillesvanwezel.bsky.social – @unileiden.bsky.social
🦠 @iandealidbury.bsky.social – @sheffielduni.bsky.social

Join us at in Malaga on 3-7 November!
Register now: 6thplantmicrobiomesymposium2025.com
September 2, 2025 at 3:16 PM
Reposted by Molecular Microbiology, University of Sheffield
drn-sheffield.bsky.social
Congratulations to Dr Claire Turner @molmicrosheffield.bsky.social and DRN's Professor Ivana Barbaric on their excellent talks in the University of Sheffield @sheffielduni.bsky.social School of Biosciences Inaugural Lecture series today.

www.sheffield.ac.uk/biosciences/...

www.thebarbariclab.com
May 21, 2025 at 9:15 PM
molmicrosheffield.bsky.social
www.sheffield.ac.uk/biosciences/.... New PhD positions in our @sheffieldpps.bsky.social research cluster
World class training - International dual award PhDs in Plant & Soil Science now open
These new studentships offer a unique opportunity to join a vibrant and collaborative research community spanning two world-class institutions in Sheffield, UK and Sydney, Australia.
www.sheffield.ac.uk
May 8, 2025 at 9:18 AM
Reposted by Molecular Microbiology, University of Sheffield
robfagan.bsky.social
New paper alert 🚨
We've solved the complete structure of a C. difficile-infecting phage using cryo-EM, in both extended and contracted conformations - published today in Life Science Alliance

www.life-science-alliance.org/content/8/6/...
Molecular mechanism of bacteriophage contraction structure of an S-layer–penetrating bacteriophage
The molecular details of phage tail contraction and bacterial cell envelope penetration remain poorly understood and are completely unknown for phages infecting bacteria enveloped by proteinaceous S-l...
www.life-science-alliance.org
March 26, 2025 at 2:21 PM
molmicrosheffield.bsky.social
We recently had the pleasure of Vicky Gold presenting her labs work on filamentous phage structure #structuralbiology #phage @exeter.ac.uk @exeterunispeccoll.bsky.social
March 10, 2025 at 7:17 AM
Reposted by Molecular Microbiology, University of Sheffield
claireyt.bsky.social
The #WellcomeTrust CDA Fellowship team is fully assembled! Saikou Bah, Henna Khalid, Sona Jabang & Jess Buddle, let the #StrepA research commence 🥳🎉 @molmicrosheffield.bsky.social #UniversityofSheffield
Five people standing in front of a building
March 7, 2025 at 2:25 PM
molmicrosheffield.bsky.social
Exciting times ahead for @claireyt.bsky.social
claireyt.bsky.social Claire Turner @claireyt.bsky.social · Mar 7
The #WellcomeTrust CDA Fellowship team is fully assembled! Saikou Bah, Henna Khalid, Sona Jabang & Jess Buddle, let the #StrepA research commence 🥳🎉 @molmicrosheffield.bsky.social #UniversityofSheffield
Five people standing in front of a building
March 7, 2025 at 3:05 PM
molmicrosheffield.bsky.social
Meet our Independent Research Fellows funded by @ukri.org @wellcometrust.bsky.social @royalsociety.org @sheffielduni.bsky.social housed within our cluster (including affiliated). We are always open to discuss future opportunities for scientists wishing to start their independent research groups.
February 18, 2025 at 12:47 PM
Reposted by Molecular Microbiology, University of Sheffield
jpjhall.bsky.social
I'm delighted to announce that the 2025 @microbiologysociety.org meeting on "Understanding and predicting microbial evolutionary dynamics" will be held in Liverpool 26-27 November 2025! Abstract submission will open soon... #microsky 🧪🧫🦠 microbiologysociety.org/event/societ...
Understanding and predicting microbial evolutionary dynamics - 2025 meeting
microbiologysociety.org
February 18, 2025 at 9:50 AM
Reposted by Molecular Microbiology, University of Sheffield
iandealidbury.bsky.social
academic.oup.com/ismej/advanc... advanced online release of our new paper. Great work from 2 undergraduates, 1 masters, 1 PhD @hannahmartin.bsky.social , and my research tech @lailamoushtaq.bsky.social ! smashed it. #glycobiology #plantmicrobiome #Bacteroidota @molmicrosheffield.bsky.social
Metabolism of hemicelluloses by root-associated Bacteroidota species
Abstract. Bacteroidota species are enriched in the plant microbiome and provide several beneficial functions for their host, including disease suppression.
academic.oup.com
February 7, 2025 at 10:55 AM
Reposted by Molecular Microbiology, University of Sheffield
robfagan.bsky.social
Every now and then we manage to nab one of the really nice meeting rooms for our regular @molmicrosheffield.bsky.social cluster catch up
A photo of the Council Room in Firth Court at the University of Sheffield. The room has a modern interior but retains the original stone-framed picture windows overlooking Weston Park The view from one of the picture windows showing the park and the corner of the VCs octagonal tower
February 7, 2025 at 6:47 PM
molmicrosheffield.bsky.social
www.nature.com/articles/s41... a timely commentary on microbiome research
www.nature.com
February 1, 2025 at 11:37 AM
Reposted by Molecular Microbiology, University of Sheffield
corrigar.bsky.social
We're hiring! Two new tenure track fellowships available in AMR at the UCD School of Medicine and the Vet School

www.ucd.ie/adastrafello...
Becoming an Ad Astra Fellow - UCD Ad Astra Fellows
www.ucd.ie
January 29, 2025 at 7:04 AM
molmicrosheffield.bsky.social
A few weeks back we had the pleasure of @javierabellon.bsky.social from @newcastleuni.bsky.social presenting work on vitamin B12 import in gut bacteria
January 31, 2025 at 4:06 PM
molmicrosheffield.bsky.social
Fantastic weather for a fantastic talk from @pstansfeld.bsky.social #moleculardynamics @davidroper2.bsky.social you are doing some great stuff down there
January 30, 2025 at 7:29 PM