Seema
@molbioinfo.bsky.social
Loves Bioinformatics and Computational biology to the 🍵.
Pan-cancer systems biology, LncRNA interactions with proteins and mRNA, molecular dynamics, immunoinformatics.
Member, The National Academy of Sciences, India
Pan-cancer systems biology, LncRNA interactions with proteins and mRNA, molecular dynamics, immunoinformatics.
Member, The National Academy of Sciences, India
🧪
Thought of the day:
Penned by me: "An abstract Abstract doesn't age well". Or does it?
#science
#NobelPrize
#abstract
Thought of the day:
Penned by me: "An abstract Abstract doesn't age well". Or does it?
#science
#NobelPrize
#abstract
October 8, 2025 at 10:09 AM
🧪
Thought of the day:
Penned by me: "An abstract Abstract doesn't age well". Or does it?
#science
#NobelPrize
#abstract
Thought of the day:
Penned by me: "An abstract Abstract doesn't age well". Or does it?
#science
#NobelPrize
#abstract
Reposted by Seema
📣 Don't miss this new Review!
Interplay between RNA-protein interactions and RNA structures in gene regulation
🔓 buff.ly/pu6TpVa
🖊️ @rnaminni.bsky.social
#RBPs #RNA #RNAbiology #RNAbindingproteins #RNAbinding #RNAstructure
Interplay between RNA-protein interactions and RNA structures in gene regulation
🔓 buff.ly/pu6TpVa
🖊️ @rnaminni.bsky.social
#RBPs #RNA #RNAbiology #RNAbindingproteins #RNAbinding #RNAstructure
September 29, 2025 at 9:01 AM
📣 Don't miss this new Review!
Interplay between RNA-protein interactions and RNA structures in gene regulation
🔓 buff.ly/pu6TpVa
🖊️ @rnaminni.bsky.social
#RBPs #RNA #RNAbiology #RNAbindingproteins #RNAbinding #RNAstructure
Interplay between RNA-protein interactions and RNA structures in gene regulation
🔓 buff.ly/pu6TpVa
🖊️ @rnaminni.bsky.social
#RBPs #RNA #RNAbiology #RNAbindingproteins #RNAbinding #RNAstructure
Hello RNA world! Any new news?
October 2, 2025 at 12:44 PM
Hello RNA world! Any new news?
MtDNA incorporating ribonucleotides and not deoxyribonucleotides increases inflammation. Interesting article:
x.com/davidasincla...
x.com/davidasincla...
x.com
September 30, 2025 at 3:58 AM
MtDNA incorporating ribonucleotides and not deoxyribonucleotides increases inflammation. Interesting article:
x.com/davidasincla...
x.com/davidasincla...
🧪Intellectuals,
Selection for the prestigious National Academy of Sciences (India) Membership is a joy!
Yours truly, Ph.D, MNASc 😀
Grateful to everyone who have stood by me rock solid in this scenic and transformative journey. Heartfelt Thank you to The National Academy of Sciences, India...
Selection for the prestigious National Academy of Sciences (India) Membership is a joy!
Yours truly, Ph.D, MNASc 😀
Grateful to everyone who have stood by me rock solid in this scenic and transformative journey. Heartfelt Thank you to The National Academy of Sciences, India...
July 27, 2025 at 11:03 AM
🧪Intellectuals,
Selection for the prestigious National Academy of Sciences (India) Membership is a joy!
Yours truly, Ph.D, MNASc 😀
Grateful to everyone who have stood by me rock solid in this scenic and transformative journey. Heartfelt Thank you to The National Academy of Sciences, India...
Selection for the prestigious National Academy of Sciences (India) Membership is a joy!
Yours truly, Ph.D, MNASc 😀
Grateful to everyone who have stood by me rock solid in this scenic and transformative journey. Heartfelt Thank you to The National Academy of Sciences, India...
Happy to share our latest paper using machine-learning-QSAR on ChEMBL dataset. We identified and designed novel inhibitors for Acid Ceramidase inhibition in Glioblastoma using SHAP-based mechanistic interpretations. Thankful to proactive Reviewers and Editors.
rdcu.be/exD3a
rdcu.be/exD3a
An innovative machine learning-based QSAR approach for prediction and structural analysis of novel/repurposed acid ceramidase (ASAH1) inhibitors for glioblastoma therapy
rdcu.be
July 24, 2025 at 9:09 AM
Happy to share our latest paper using machine-learning-QSAR on ChEMBL dataset. We identified and designed novel inhibitors for Acid Ceramidase inhibition in Glioblastoma using SHAP-based mechanistic interpretations. Thankful to proactive Reviewers and Editors.
rdcu.be/exD3a
rdcu.be/exD3a
Interesting, so sharing here:
x.com/nlarusstone/...
x.com/nlarusstone/...
x.com
x.com
January 3, 2025 at 3:33 PM
Interesting, so sharing here:
x.com/nlarusstone/...
x.com/nlarusstone/...
And here I was wondering RNA Capping at the first mention of the word 'cap'...caps impart efficient translation and stability to mRNA... 🤔
I strongly disagree with the idea of caps. Caps are always brought up because "mega-labs are bad!!" Regardless of whether they are good or bad, mega-labs are rarely affected by caps. Instead, it is middle-class labs that are shifted towards subsistence. That is bad for the scientific ecosystem, IMO.
Dear @pnas.org ,
I strongly disagree. I believe that in the current funding environment, caps to individual labs and PIs are and would be absolutely crucial for sustaining scientific innovation. Would you consider a counter opinion piece? Who’d be interested in writing one with me?
I strongly disagree. I believe that in the current funding environment, caps to individual labs and PIs are and would be absolutely crucial for sustaining scientific innovation. Would you consider a counter opinion piece? Who’d be interested in writing one with me?
November 28, 2024 at 3:07 AM
And here I was wondering RNA Capping at the first mention of the word 'cap'...caps impart efficient translation and stability to mRNA... 🤔
Reposted by Seema
The great Matterhorn in all its glory… A classic shot from the Swiss alps, but the light was too good to not click this one.
#bluesky #photography #mountains #nature #landscape #landscapephotography #naturephotography
#bluesky #photography #mountains #nature #landscape #landscapephotography #naturephotography
November 26, 2024 at 9:55 AM
The great Matterhorn in all its glory… A classic shot from the Swiss alps, but the light was too good to not click this one.
#bluesky #photography #mountains #nature #landscape #landscapephotography #naturephotography
#bluesky #photography #mountains #nature #landscape #landscapephotography #naturephotography
Zhu et al. discovered that tRNAs also play an important role in regulating mRNA degradation during translation. Data revealed that specific tRNAs that decode arginine codons directly recruit the CCR4-NOT complex to translating ribosomes, thereby promoting mRNA turnover.
November 22, 2024 at 12:51 AM
RNA aficianados,
Just attended my first seminar series at RNA Collaborative - The RNA Institute, SUNY University at Albany yesterday. It is awesome science and a great way to stay updated in everything RNA. Registration is free:
www.rnasociety.org/rna-collabor...
#rnabiology
#rnasky
🧪
Just attended my first seminar series at RNA Collaborative - The RNA Institute, SUNY University at Albany yesterday. It is awesome science and a great way to stay updated in everything RNA. Registration is free:
www.rnasociety.org/rna-collabor...
#rnabiology
#rnasky
🧪
RNA Collaborative Seminar Series
www.rnasociety.org
November 21, 2024 at 12:32 AM
RNA aficianados,
Just attended my first seminar series at RNA Collaborative - The RNA Institute, SUNY University at Albany yesterday. It is awesome science and a great way to stay updated in everything RNA. Registration is free:
www.rnasociety.org/rna-collabor...
#rnabiology
#rnasky
🧪
Just attended my first seminar series at RNA Collaborative - The RNA Institute, SUNY University at Albany yesterday. It is awesome science and a great way to stay updated in everything RNA. Registration is free:
www.rnasociety.org/rna-collabor...
#rnabiology
#rnasky
🧪
Reposted by Seema
Here is a paper where I would just like to say "Thank you" to the authors.
I thoroughly enjoyed this.
I hope you do too.
#GENESky
#RNAsky
#CANsky
#genomics
#bioinformatics
🧪
🧬💻
🔎 microproteins
www.cell.com/cell-reports...
I thoroughly enjoyed this.
I hope you do too.
#GENESky
#RNAsky
#CANsky
#genomics
#bioinformatics
🧪
🧬💻
🔎 microproteins
www.cell.com/cell-reports...
RNA splicing junction landscape reveals abundant tumor-specific transcripts in human cancer
Li et al. thoroughly analyzed RNA splicing junctions in 34,775 samples and identified
29,051 tumor-specific transcripts that may serve as cancer driver genes, neoantigens,
and circulating biomarkers.
www.cell.com
November 16, 2024 at 7:54 PM
Here is a paper where I would just like to say "Thank you" to the authors.
I thoroughly enjoyed this.
I hope you do too.
#GENESky
#RNAsky
#CANsky
#genomics
#bioinformatics
🧪
🧬💻
🔎 microproteins
www.cell.com/cell-reports...
I thoroughly enjoyed this.
I hope you do too.
#GENESky
#RNAsky
#CANsky
#genomics
#bioinformatics
🧪
🧬💻
🔎 microproteins
www.cell.com/cell-reports...
November 20, 2024 at 4:59 PM
...to resurrect an old blog post from 2015:
Your Operating System on a Thumbdrive – A Snippet
At the heart of every cell's 'operating system' you find the ribosomes, these ingenious nano‑machines that translate messenger RNA (mRNA) into all kinds of...
schaechter.asmblog.org/schaechter/2...
Your Operating System on a Thumbdrive – A Snippet
At the heart of every cell's 'operating system' you find the ribosomes, these ingenious nano‑machines that translate messenger RNA (mRNA) into all kinds of...
schaechter.asmblog.org/schaechter/2...
November 20, 2024 at 4:51 PM
Molecular dynamics aficionados! Which is the most accurate RNA force-field currently?
#rnabiology
#computationalbiology
#rnasky
🧪
#rnabiology
#computationalbiology
#rnasky
🧪
November 20, 2024 at 4:50 PM
Molecular dynamics aficionados! Which is the most accurate RNA force-field currently?
#rnabiology
#computationalbiology
#rnasky
🧪
#rnabiology
#computationalbiology
#rnasky
🧪
November 18, 2024 at 10:49 AM
Reposted by Seema
Got birds?
Reply or quote this with your pics; we’d love to see them
📷🪶
Reply or quote this with your pics; we’d love to see them
📷🪶
November 13, 2024 at 6:27 PM
Got birds?
Reply or quote this with your pics; we’d love to see them
📷🪶
Reply or quote this with your pics; we’d love to see them
📷🪶
Reposted by Seema
Let's make a thread of RNA-related conferences in 2025 🧵 (add missing!)
November 13, 2024 at 6:03 AM
Let's make a thread of RNA-related conferences in 2025 🧵 (add missing!)
@ijayas.bsky.social please add me to Biophysics starter pack. Thanks.
November 13, 2024 at 12:46 AM
@ijayas.bsky.social please add me to Biophysics starter pack. Thanks.
