Moin Sheam
banner
moinsheam.bsky.social
Moin Sheam
@moinsheam.bsky.social
PhD student at UNC Charlotte l Marine microbial ecologist l Study giant viruses 🦠
🎓 Ghent University / Sorbonne alum
He/him
https://sites.google.com/uncc.edu/microbial-ecology-lab/home
Pinned
My first PhD paper is out in @isme-microbes.bsky.social
We found that giant viruses are associated with carbon export to the deep ocean, supporting the viral shuttle hypothesis.

Thanks to @oceanmicrobes.bsky.social for supervising the study!

academic.oup.com/ismej/articl...
Vertical transport and spatiotemporal dynamics of giant viruses in the North Pacific subtropical gyre
Abstract. Nucleocytoplasmic large DNA viruses, or “giant viruses,” are prevalent in marine environments, infecting diverse eukaryotic lineages and influenc
academic.oup.com
Reposted by Moin Sheam
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
www.science.org
October 6, 2025 at 11:31 AM
Reposted by Moin Sheam
Reposted by Moin Sheam
Very proud of the work from lab members and collaborators that coincidentally came out today www.pnas.org/doi/10.1073/... and www.nature.com/articles/s41.... A bacterial and viral pathogen associated with mass mortality in seastars and oysters. @kevinzhong2006.bsky.social @rhizalyssa.bsky.social
August 5, 2025 at 12:44 AM
Reposted by Moin Sheam
our paper is online! rdcu.be/exXBX . Who would have thought that some #giantviruses not only have #histones, but even histone variants that make weird #nucleosomes (pdb 9CVT). Fantastic work from Ale Villalta and Chelsea Toner, with Hugo Bisio @molbiolgv.bsky.social and Chantal Abergel
Melbournevirus encodes a shorter H2B-H2A doublet histone variant that forms structurally distinct nucleosome structures
Nature Communications - Melbournevirus encodes a conserved shorter H2B-H2A doublet variant. Here the authors report a cryo-EM structure of a nucleosome-like particle reconstituted with viral H4-H3...
rdcu.be
July 26, 2025 at 1:43 PM
Reposted by Moin Sheam
Funded postdoc + PhD opportunities in marine microbial ecology! Please share with folks that might be interested.

Start date is flexible (fall 2025 to summer 2026)

More about the lab + applying (Postdoc rolling, PhD apps due Oct/Jan):
sites.google.com/uncc.edu/mic...
Luo Lab - Microbial Ecology - join
The Luo Lab is accepting applications for funded Postdoc and PhD opportunities. Details below. Lab members will have access to state-of-the art wet lab, and computing, and sequencing resources, inclu...
sites.google.com
July 8, 2025 at 2:52 PM
Reposted by Moin Sheam
PhD opportunity in marine virus eco-evo dynamics

Joint CNRS–UBC program: @cnrsbiologie.bsky.social × @ubcoceans.bsky.social

📍 Banyuls-sur-Mer, France (LBBM UMR8176)
🗓️ Start: Oct 2025 | Duration: 3 years
🔍 Skills: Modelling, Bioinformatics, Marine Virology

🔗 Apply: emploi.cnrs.fr/Offres/Docto...
Portail Emploi CNRS - Offre d'emploi - Contract doctoral M/F- integrative biology of photosynthetic organisms and associated microorganisms
emploi.cnrs.fr
June 17, 2025 at 11:07 AM
My first PhD paper is out in @isme-microbes.bsky.social
We found that giant viruses are associated with carbon export to the deep ocean, supporting the viral shuttle hypothesis.

Thanks to @oceanmicrobes.bsky.social for supervising the study!

academic.oup.com/ismej/articl...
Vertical transport and spatiotemporal dynamics of giant viruses in the North Pacific subtropical gyre
Abstract. Nucleocytoplasmic large DNA viruses, or “giant viruses,” are prevalent in marine environments, infecting diverse eukaryotic lineages and influenc
academic.oup.com
June 26, 2025 at 6:34 PM
Reposted by Moin Sheam
Lab’s first publication as #newPI @isme-microbes.bsky.social 😃

We observed evidence supporting the viral shuttle hypothesis in giant viruses. We also observed convergent evolution amongst giant viruses and bacteriophages to light-energy and nutrient limitation.

academic.oup.com/ismej/articl...
Vertical transport and spatiotemporal dynamics of giant viruses in the North Pacific subtropical gyre
Abstract. Nucleocytoplasmic large DNA viruses, or “giant viruses,” are prevalent in marine environments, infecting diverse eukaryotic lineages and influenc
academic.oup.com
June 26, 2025 at 12:22 AM
Reposted by Moin Sheam
Terrific PhD science opportunity in the world of marine viral ecology and evolution with a stellar team in S. France working with Marcelino Suzuki, David Demory, and Sheree Yau.

Applications due July 8.

👇
PhD opportunity in marine virus eco-evo dynamics

Joint CNRS–UBC program: @cnrsbiologie.bsky.social × @ubcoceans.bsky.social

📍 Banyuls-sur-Mer, France (LBBM UMR8176)
🗓️ Start: Oct 2025 | Duration: 3 years
🔍 Skills: Modelling, Bioinformatics, Marine Virology

🔗 Apply: emploi.cnrs.fr/Offres/Docto...
Portail Emploi CNRS - Offre d'emploi - Contract doctoral M/F- integrative biology of photosynthetic organisms and associated microorganisms
emploi.cnrs.fr
June 17, 2025 at 8:18 PM
Reposted by Moin Sheam
New from the Carter Lab!

Led by @bhuwanabbot.bsky.social, we sequenced almost twice as many complete genomes as were available for the endofungal Mycetohabitans genus.

Unsurprisingly, they are a little weird, giving us insight into endosymbiotic genome changes 🧬 🦠
www.biorxiv.org/content/10.1...
www.biorxiv.org
June 17, 2025 at 8:55 PM
Reposted by Moin Sheam
Happy to have contributed to this great article: #Protist genomics: key to understanding eukaryotic evolution. Congrats Alexandra Schoenle et al. #ProtistsOnSky
authors.elsevier.com/sd/article/S...
June 13, 2025 at 6:43 AM
Reposted by Moin Sheam
June 7, 2025 at 2:48 AM
Reposted by Moin Sheam
Vertical transport and spatiotemporal dynamics of giant viruses in the North Pacific Subtropical Gyre | The ISME Journal | Oxford Academic https://academic.oup.com/ismej/advance-article/doi/10.1093/ismejo/wraf094/8140627?login=true
Vertical transport and spatiotemporal dynamics of giant viruses in the North Pacific Subtropical Gyre
Abstract. Nucleocytoplasmic large DNA viruses, or “giant viruses,” are prevalent in marine environments, infecting diverse eukaryotic lineages and influenc
dx.doi.org
May 26, 2025 at 4:33 AM
Reposted by Moin Sheam
Lab's first preprint! #newPI

We show that viruses are active agents that recycle carbon fixed by productive chemoautotrophs, shaping our understanding of carbon cycling in redox-active ecosystems.

www.biorxiv.org/content/10.1...

@julesdeep.bsky.social @gtrubl.bsky.social @mepjoe.bsky.social
Virus-mediated recycling of chemoautotrophic biomass
Aquatic environments absorb ~2.5 gigatonnes of atmospheric carbon each year, more than the carbon stored in the atmosphere, soils, and all biomass combined. Primary producers transform this dissolved ...
www.biorxiv.org
May 28, 2025 at 9:36 PM
Reposted by Moin Sheam
Another position within the PHYVIR project 😁.
Are you looking for an interesting Postdoc (45 month!) on marine viral ecology? Check out the ad below.
workingat.nioz.nl/o/postdoc-po...
NIOZ - Postdoc position (45 months):“Marine phytoplankton – virus interactions and loss rates from small to ocean scale”
The Department of Marine Microbiology and Biogeochemistry (MMB; principal investigator and PHYVIR project coordinator Prof. Dr. Corina Brussaard) of NIOZ is looking for a talented and dedicated Postdo
workingat.nioz.nl
May 3, 2025 at 6:40 AM
Reposted by Moin Sheam
Latest findings on cryptic infection of giant viruses published in @ScienceMagazine. We discovered a large virus hiding within a green algal genome producing virions.
www.science.org/doi/10.1126/...
Cryptic infection of a giant virus in a unicellular green alga
Latency is a common strategy in a wide range of viral lineages, but its prevalence in giant viruses remains unknown. Here we describe a 617 kbp integrated giant viral element in the model green alga C...
www.science.org
April 12, 2025 at 7:56 AM