Mona Wellhäusser
LightNews LightNews
banner
mofrawe.bsky.social
Mona Wellhäusser
@mofrawe.bsky.social
30 followers 23 following 1 posts
PhD Student @ Karlsruhe Institute of Technology.
Investigating structural changes in zebrafish nuclei upon gene activation.
Posts Replies Media Videos
Reposted by Mona Wellhäusser
lennarthilbert.bsky.social
Last night Science Slam with a full house at Tollhaus, as part of @kit.edu Science Week. As one of four slammers, our PhD student Mona Wellhäusser @mofrawe.bsky.social entertained a huge audience, putting fish in jello for microscopy, (optically) slicing a pumpkin. Great show, fantastic atmosphere!
October 18, 2025 at 6:58 AM
Reposted by Mona Wellhäusser
lennarthilbert.bsky.social
If you are at GBM compact "Focus on Condensate Biology", we will be happy to talk to you at our lab's posters:

Mona Wellhäuser, MC15 @mofrawe.bsky.social
Yuzhi Bao, CA03 @yuzhibao.bsky.social
Lennart Hilbert, MC06

Conference abstracts:

gbm-compact.org/abstracts.html

*sketch added as click bait
September 18, 2025 at 11:52 AM
Reposted by Mona Wellhäusser
kit.edu
Molekulare #Bionik: Der Zellkern als Vorbild für DNS-basierte #Computerchips. Forschende des #KITKarlsruhe (u. a. @lennarthilbert.bsky.social) nutzen zelluläre Informationsverarbeitung als Inspiration für die #Biotechnologie. www.kit.edu/kit/pi_2025_...
Um das Verhalten der DNS nachvollziehbar und vorhersagbar zu machen, kombinieren die Forschenden Laborexperimente mit Computersimulationen.
September 9, 2025 at 11:02 AM
Reposted by Mona Wellhäusser
lennarthilbert.bsky.social
"Chromatin-associated condensates as an inspiration for the system architecture of future DNA computers"

Highly conceptual Perspective article, supported by fresh data & simulations from our group. Containing my now 40 years of accumulated "wisdom".

nyaspubs.onlinelibrary.wiley.com/doi/10.1111/...
An analogy between the architectures of electronic computers and transcription factories. (A) Von Neumann computer architecture, in which a CPU is connected to different blocks in a working memory. (B) A transcription factory centrally stores the molecular transcription machinery and can selectively access genes. (C) The operation principle of a CPU-memory architecture based on synthetic DNA nanostructures.
September 8, 2025 at 1:50 PM
Reposted by Mona Wellhäusser
lennarthilbert.bsky.social
Our first expansion microscopy results. Imaged today on "normal" Zeiss LSM 900, revealing chromatin and RNA polymerase II clusters at an unreal level of detail.

Our PhD student @mofrawe.bsky.social learned the protocol from amazing @mpownall.bsky.social 🙏

Months of preparation are paying off now!
August 14, 2025 at 6:28 PM
Reposted by Mona Wellhäusser
lennarthilbert.bsky.social
Posters & pizza workshop event between @kreysinglab.bsky.social , Levkin lab, and ourselves Hilbert lab, also joined by Miha Modic @paraspeckle.bsky.social

Now already the second annual repeat, third will make it a tradition 😀

It also happened to be Pavel’s bday, hence cake and champagne 🥂
July 18, 2025 at 9:04 PM
Reposted by Mona Wellhäusser
lennarthilbert.bsky.social
Guten Morgen an unsere deutschsprachigen Lesenden 🌞

Hier die @kit.edu Pressemitteilung zu unserer kürzlich erschienenen Arbeit im Biophysical Journal.

Wir untersuchen, wie bewegliche Gensequenzen das Genom “umkrempeln“

www.linkedin.com/posts/lennar...
Genetik: Wie springende DNA das Erbgut umkrempelt | Lennart Hilbert
KIT Pressemitteilung zu unserer kürzlich veröffentlichten Studie im Biophysical Journal. Mit Roshan Prizak und Aaron Gadzekpo als Erstautoren, super Arbeit! https://lnkd.in/esdBphJ5
www.linkedin.com
May 24, 2025 at 6:49 AM
Reposted by Mona Wellhäusser
lennarthilbert.bsky.social
#FluorescenceFriday fixed cell data over the cell cycle in zebrafish embryo, Hoechst & IG against active enhancers and recruited Pol II. Recorded by @mofrawe.bsky.social on @visitech.bsky.social iSIM, prepared during Masters practical, credit also to @yuzhibao.bsky.social & TA Alicia Günthel
January 31, 2025 at 2:07 PM
Reposted by Mona Wellhäusser
lennarthilbert.bsky.social
A developing @zebrafishrock.bsky.social egg for the weekend ☺️

youtu.be/8Jm-CrbtXYY?...

Recorded and prepared by PhD student @mofrawe & Bachelor student Timo Schreiber.

For full data and description: doi.org/10.5281/zeno...
One-cell-stage to 21-somite-stage development of a zebrafish embryo
The video shows the development of a zebrafish embryo from one-cell-stage to 21-somite-stage. Unedited videos, as well as a sped-up version are available. Videos were recorded and edited by Mona Wellhäusser and Timo Schreiber in the research group headed by Lennart Hilbert at the Institute of Biological and Chemical Systems, Karlsruhe Institute of Technology. Full data and citable version on Zenodo: https://doi.org/10.5281/zenodo.12547356
youtu.be
June 28, 2024 at 6:40 PM