Mike Lacy
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mlacyphd.bsky.social
Mike Lacy
@mlacyphd.bsky.social
1.1K followers 1.1K following 140 posts
#OpenScience supporter, I work @Addgene.bsky.social curating DNA and web content. Previously worked at ASCB, publishing, Yale Biophysics PhD. He/him
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mlacyphd.bsky.social
reposting with alt text - Top cited antibodies are not always the best option! (and link to the paper cited: doi.org/10.7554/eLif...) 🧪
A photo of a presentation slide titled "Top cited antibodies are not always the best option". Two pie charts and their annotations indicate "31% of publications used antibodies that passed our KO validation" and "69% used antibodies that failed KO validation" for western blot; and "22% of publications used antibodies that passed our KO validation" and "78% used antibodies that failed KO validation" for Immunofluorescence. The slide includes a reference to Ayoubi et al. eLife 2023 (link to paper: https://doi.org/10.7554/eLife.91645.2).
September 12, 2025 at 1:50 PM
mlacyphd.bsky.social
Screenshot of an array of biomedical icons, including viruses, anatomical parts, cells, proteins, lab equipment and more. Image from NIH Bioart homepage https://bioart.niaid.nih.gov/.
October 30, 2024 at 1:52 PM
mlacyphd.bsky.social
It's a beautiful day to share plasmids - blue skies at the @addgene.bsky.social office!
Photo of Addgene's lab/office building, with bright blue sky and white fluffy clouds visible both above and reflected in the windows.
August 21, 2024 at 4:57 PM
mlacyphd.bsky.social
Super cool - Unreal video game engine renderings of biological systems. Be sure to check out the supplemental videos! 👀
www.biorxiv.org/content/10.1...
Figure 3 from Chen 2023. Four panels showing cryoET data of NL63 coronavirus spike proteins, viral protein model based on subtomogram averages, and two renderings of atomic models of the viral particle floating in the sunny sky.
February 29, 2024 at 1:48 PM
mlacyphd.bsky.social
Wrapped up #CellBio2023 with some very cool talks on biosensors, optogenetic tools, and more. Plus one more meetup with my former advisor @berrolab.bsky.social
Photo of me and Julien Berro
December 6, 2023 at 5:38 PM
mlacyphd.bsky.social
Ready for another day of #CellBio2023! It's nice to be local - doing my part to reduce the carbon footprint of this conference 🚲
Me, wearing a bike helmet, sunglasses, and jacket, in front of a bike parked at the convention center.
December 5, 2023 at 2:16 PM
mlacyphd.bsky.social
Kicking off day 2 of #CellBio2023 with a packed house for the Porter Prize lecture, David Drubin.
December 4, 2023 at 2:43 PM
mlacyphd.bsky.social
Open sharing speeds science! #ILovebioRxiv #CellBio2023 @biorxivpreprint.bsky.social
Did you know that you can deposit plasmids @addgene.bsky.social before they are published? We love preprints! (or you can even deposit plasmids without a manuscript at all)
Me standing in front of a backdrop with bioRxiv logo, holding a whiteboard that says "I love bioRxiv because... open sharing speeds science!"
December 3, 2023 at 6:25 PM
mlacyphd.bsky.social
Our both is open! @addgene.bsky.social (next to the Career Center) stop by to chat about plasmids, antibodies, viruses, open science, and more!
Conference exhibit hall, with an arrow pointing out Addgene's booth next to the career center
December 3, 2023 at 2:46 PM
mlacyphd.bsky.social
It may be a rainy day out there, but I'm ready for some science! #CellBio2023
Rainy cityscape view of South Boston Me, wearing an Addgene branded shirt and jacket, face mask, and conference name badge.
December 3, 2023 at 1:37 PM
mlacyphd.bsky.social
I'll be live and in person at ASCB #CellBio2023! Find me at the @addgene.bsky.social booth (no. 204), checking out some sessions, or wandering the posters👀
Banner image with the text "Cell Bio 23, an ASCB|EMBO Meeting. December 2-6, Boston, MA"
November 20, 2023 at 3:18 PM
mlacyphd.bsky.social
"High JIF does not correlate with lasting impact"
Smart analysis of long-term impact by Heiko Heerklotz:
www.cell.com/biophysj/ful...
Scatter plot of Cited half-life (years) versus Journal Impact Factor, with a variety of journals' data highlighted. Many high-impact factor journals (like Cell, Nature, Science, PNAS) have lower cited half-life than lower impact factor journals (like Biophysical Journal, FEBS Letters, JMB, Biopolymers).
October 5, 2023 at 1:38 PM