@mkappelman.bsky.social
Reposted
Excited to share our preprint on #HemeSky: "MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia"! @delwelruud.bsky.social and co-authors! www.biorxiv.org/content/10.1... [1/15]
MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia
Enhancer translocations, due to 3q26 rearrangements, drive out-of-context MECOM expression in an aggressive subtype of acute myeloid leukemia (AML). Direct depletion of MECOM using an endogenous auxin...
www.biorxiv.org
January 6, 2025 at 3:46 PM
Excited to share our preprint on #HemeSky: "MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia"! @delwelruud.bsky.social and co-authors! www.biorxiv.org/content/10.1... [1/15]