mitenjain.bsky.social
@mitenjain.bsky.social
Reposted by mitenjain.bsky.social
As mentioned above this is still very early R&D work, not ready for release yet.
We are generating more data and @stoibs11.bsky.social's team has got plenty of ML magic tricks to significantly improve the performance of the models.
We are generating more data and @stoibs11.bsky.social's team has got plenty of ML magic tricks to significantly improve the performance of the models.
November 28, 2024 at 12:12 PM
As mentioned above this is still very early R&D work, not ready for release yet.
We are generating more data and @stoibs11.bsky.social's team has got plenty of ML magic tricks to significantly improve the performance of the models.
We are generating more data and @stoibs11.bsky.social's team has got plenty of ML magic tricks to significantly improve the performance of the models.
Reposted by mitenjain.bsky.social
We have been busing working on models to detect all 2'Ome-RNA modified nucleotides on top of PseudoU, m6A, m5C and Inosine using @nanoporetech.com direct RNA sequencing.
This is still very preliminary but here are a few examples of what it looks like on Human #rRNA prepared with standard lib prep 🤩
This is still very preliminary but here are a few examples of what it looks like on Human #rRNA prepared with standard lib prep 🤩
November 28, 2024 at 12:12 PM
We have been busing working on models to detect all 2'Ome-RNA modified nucleotides on top of PseudoU, m6A, m5C and Inosine using @nanoporetech.com direct RNA sequencing.
This is still very preliminary but here are a few examples of what it looks like on Human #rRNA prepared with standard lib prep 🤩
This is still very preliminary but here are a few examples of what it looks like on Human #rRNA prepared with standard lib prep 🤩
Reposted by mitenjain.bsky.social
We are proud to announce a collaboration with UK Biobank to create the world’s first large-scale #epigenetic dataset of 50k participants. The dataset will unlock crucial insights into how #epigenetics drives disease & the breakthroughs to treat them.
Read more: nanoporetech.com/news/oxford-...
Read more: nanoporetech.com/news/oxford-...
November 27, 2024 at 9:16 AM
We are proud to announce a collaboration with UK Biobank to create the world’s first large-scale #epigenetic dataset of 50k participants. The dataset will unlock crucial insights into how #epigenetics drives disease & the breakthroughs to treat them.
Read more: nanoporetech.com/news/oxford-...
Read more: nanoporetech.com/news/oxford-...
Reposted by mitenjain.bsky.social
This is worth looking at. Trying some genomes we have assembled with earlier versions of hifiasm, hifiasm plus herro and then this new version of hifiasm. The early assembly results suggest that now hifiasm alone is equivalent to what we got with herro but with less compute!
Exciting news! The latest hifiasm release from Haoyu Cheng and Heng Li adds beta support for @nanoporetech.com simplex R10 reads. Initial results look very promising. 🚀
Check it out: github.com/chhylp123/hi...
Check it out: github.com/chhylp123/hi...
Release Hifiasm-0.21.0-r686 · chhylp123/hifiasm
Since Hifiasm-0.20.0 (r639):
New Feature: Introduced a beta module for ONT assembly using ONT simplex R10 reads. To enable this feature, add the --ont option as shown below:
hifiasm -t64 --ont -o...
github.com
November 28, 2024 at 12:58 PM
This is worth looking at. Trying some genomes we have assembled with earlier versions of hifiasm, hifiasm plus herro and then this new version of hifiasm. The early assembly results suggest that now hifiasm alone is equivalent to what we got with herro but with less compute!
Thank you @theoreticalfun.bsky.social and @danrdanny.bsky.social!
September 14, 2023 at 1:29 PM
Thank you @theoreticalfun.bsky.social and @danrdanny.bsky.social!