@mitchell-lab.bsky.social
Regulation of transcription, stem cells, and trying to figure out the regulatory code. The Mitchell Lab at the U of Toronto.
Come work with us in this vibrant and diverse department csb.utoronto.ca
Department of Cell & Systems Biology
The Department of Cell & Systems Biology (CSB) advances research and teaching in some of the most dynamic and vital areas of biological research.
csb.utoronto.ca
September 19, 2025 at 9:33 PM
Come work with us in this vibrant and diverse department csb.utoronto.ca
Welcome Felix, we’re thrilled to have you join CSB@UofT
July 8, 2025 at 7:20 PM
Welcome Felix, we’re thrilled to have you join CSB@UofT
This was a big collaborative effort started by Sakthi D Moorthy, now at CCRM, and brought to the finish by @itobiaslab.bsky.social now at @uofguelph.bsky.social
Thank you to all the team and to CIHR for funding our efforts to understand gene expression regulation in the brain!
Thank you to all the team and to CIHR for funding our efforts to understand gene expression regulation in the brain!
January 30, 2025 at 1:49 AM
This was a big collaborative effort started by Sakthi D Moorthy, now at CCRM, and brought to the finish by @itobiaslab.bsky.social now at @uofguelph.bsky.social
Thank you to all the team and to CIHR for funding our efforts to understand gene expression regulation in the brain!
Thank you to all the team and to CIHR for funding our efforts to understand gene expression regulation in the brain!
The cells missing SRR2-18 shift their transcriptome and accessible chromatin away from the developing forebrain to a state more similar to the neural tube.
January 30, 2025 at 1:39 AM
The cells missing SRR2-18 shift their transcriptome and accessible chromatin away from the developing forebrain to a state more similar to the neural tube.
Deleting the Sox2 SRR2-18 enhancer cluster on both alleles causes a loss of neural stem cell self renewal at higher passages.
January 30, 2025 at 1:35 AM
Deleting the Sox2 SRR2-18 enhancer cluster on both alleles causes a loss of neural stem cell self renewal at higher passages.