Mike Johansen
@mikejohansenmd.medsky.social
Primary Care doc, likes research, teaches residents, #HSR, #MEPS, #FamilyMedicine
APS exists! I've found it a couple of times.
ALS community has a push (at least locally) to get people diagnosed earlier. If you know who the subspecialists are, they'll likely work to get patients seen. In Columbus (region of a few million people), I think there are 2 clinics (that I know of).
ALS community has a push (at least locally) to get people diagnosed earlier. If you know who the subspecialists are, they'll likely work to get patients seen. In Columbus (region of a few million people), I think there are 2 clinics (that I know of).
November 11, 2025 at 12:44 PM
APS exists! I've found it a couple of times.
ALS community has a push (at least locally) to get people diagnosed earlier. If you know who the subspecialists are, they'll likely work to get patients seen. In Columbus (region of a few million people), I think there are 2 clinics (that I know of).
ALS community has a push (at least locally) to get people diagnosed earlier. If you know who the subspecialists are, they'll likely work to get patients seen. In Columbus (region of a few million people), I think there are 2 clinics (that I know of).
Other studies haven't looked at this in the HD population. I find it somewhat reassuring that it's a multi-center study. The effect size is in line with lots of CVD prevention agents (primary outcome is different than normal). I wish they had made the dataset public, so others could interrogate it.
November 11, 2025 at 12:32 PM
Other studies haven't looked at this in the HD population. I find it somewhat reassuring that it's a multi-center study. The effect size is in line with lots of CVD prevention agents (primary outcome is different than normal). I wish they had made the dataset public, so others could interrogate it.
Yeah-he put it in one of my threads on this. I think he overstates the risk that the data is biased in some manner, but I see the possibility.
November 11, 2025 at 12:27 PM
Yeah-he put it in one of my threads on this. I think he overstates the risk that the data is biased in some manner, but I see the possibility.
But what if I want it to work like this?
November 11, 2025 at 12:21 PM
But what if I want it to work like this?
So are we pretending that taking estrogen is without adverse events?
November 11, 2025 at 12:06 PM
So are we pretending that taking estrogen is without adverse events?
The end of the season was laughably bad. I was watching in 2 min increments just to finish.
November 11, 2025 at 1:41 AM
The end of the season was laughably bad. I was watching in 2 min increments just to finish.
All you need is an online portal! Just know that the launch will be terrible and you'll need to bring people in to make it work.
November 11, 2025 at 12:19 AM
All you need is an online portal! Just know that the launch will be terrible and you'll need to bring people in to make it work.
I tend to think we got lucky with statins/pak9i's as there are many lipid improvers that don't do much to reduce outcomes.
November 11, 2025 at 12:13 AM
I tend to think we got lucky with statins/pak9i's as there are many lipid improvers that don't do much to reduce outcomes.
My priors are that dialysis population is not the same as dialysis. I am curious if this is a dialysis difference or an esrd difference.
November 11, 2025 at 12:12 AM
My priors are that dialysis population is not the same as dialysis. I am curious if this is a dialysis difference or an esrd difference.
Alternatively, he could move to the beach w/a nice income.
November 10, 2025 at 7:29 PM
Alternatively, he could move to the beach w/a nice income.
Everytime I go to the ringer (which is no longer common), it feels like they spent more time on the cover art than the content.
November 10, 2025 at 5:53 PM
Everytime I go to the ringer (which is no longer common), it feels like they spent more time on the cover art than the content.
Reposted by Mike Johansen
Comically, I bet that certain patients benefit from different oil intakes. After thousands of people randomized to fish oil, we have no idea.
November 10, 2025 at 4:49 PM
Comically, I bet that certain patients benefit from different oil intakes. After thousands of people randomized to fish oil, we have no idea.
i.e. even if it is an outlier, the likelihood of benefit in a super high risk population is presumably worth the risk.
November 10, 2025 at 4:47 PM
i.e. even if it is an outlier, the likelihood of benefit in a super high risk population is presumably worth the risk.
I wouldn't be writing it into guidelines, but I'd use it clinically.
The challenge with this is that further data will likely bring the PE back closer to 1, but would require a lot of data to show this isn't beneficial.
I was dissappointed the authors didn't make the dataset public.
The challenge with this is that further data will likely bring the PE back closer to 1, but would require a lot of data to show this isn't beneficial.
I was dissappointed the authors didn't make the dataset public.
November 10, 2025 at 4:47 PM
I wouldn't be writing it into guidelines, but I'd use it clinically.
The challenge with this is that further data will likely bring the PE back closer to 1, but would require a lot of data to show this isn't beneficial.
I was dissappointed the authors didn't make the dataset public.
The challenge with this is that further data will likely bring the PE back closer to 1, but would require a lot of data to show this isn't beneficial.
I was dissappointed the authors didn't make the dataset public.
"Selective Bayesianism" is a common variant over at sensible.
November 10, 2025 at 4:30 PM
"Selective Bayesianism" is a common variant over at sensible.
I actually lied, I wouldn't start it today. I'd have started it on Saturday b/c I didn't have any sitting around the house on Friday night.
November 10, 2025 at 2:54 PM
I actually lied, I wouldn't start it today. I'd have started it on Saturday b/c I didn't have any sitting around the house on Friday night.