Miguel Ruiz Cruz
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miguel-ruiz-cruz.bsky.social
Miguel Ruiz Cruz
@miguel-ruiz-cruz.bsky.social
Postdoctoral fellow at the Manuel Tena-Sempere’s lab @pubmetts.bsky.social, biochemist and guitar player 🎸
Thank you to the Journal of Neuroendocrinology for supporting my attendance at the 7th International Melanocortin Conference through the ECR Scholarship Award. Excited to give my talk today and continue great discussions with the melanocortin community!
My pleasure to present the ECR scholarship awards sponsored by the Journal of Neuroendocrinology @jne-editor.bsky.social at the 7th International Melanocortin Conference to @albuquerquejp85.bsky.social @anikakmueller.bsky.social @miguel-ruiz-cruz.bsky.social, Roger Fan,Tanya Kaur & Isabelle Smith
September 17, 2025 at 5:59 AM
Reposted by Miguel Ruiz Cruz
NEW! Postdoctoral Fellowship Grant Writing Toolbox🖋️

Created by our early career researcher Sub-committee, this toolbox gives tips and guidance for writing your first fellowship application.

DOWNLOAD: www.neuroendo.org.uk...

Special thanks @miguel-ruiz-cruz.bsky.social
September 11, 2025 at 8:37 AM
Reposted by Miguel Ruiz Cruz
NEW! Postdoctoral Fellowship Grant Writing Toolbox🖋️

Created by our early career researcher Sub-committee, this toolbox gives tips and guidance for writing your first fellowship application.

DOWNLOAD: www.neuroendo.org.uk...

Special thanks @miguel-ruiz-cruz.bsky.social
August 21, 2025 at 1:51 PM
Reposted by Miguel Ruiz Cruz
Proud to announce the publication of our new paper describing the design, chemical synthesis and testing of a novel class of Complement 3a Receptor (C3aR) agonists and antagonists derived from the TLQP-21 peptide

@pubs.acs.org Journal of Medicinal Chemistry

pubs.acs.org/doi/10.1021/...
September 4, 2025 at 12:43 PM
Reposted by Miguel Ruiz Cruz
Great to see so many ECRs turning up to #BSNBradford2025 a day early for our career transitions workshops on academic branding and sci-comms.

Looking forward to all the exciting neuroendocrine research from all our amazing @bsneuroendo.bsky.social ECR members, in person and on science bluesky!

🧠📈🧪
August 31, 2025 at 4:34 PM
Reposted by Miguel Ruiz Cruz
🏆 CONGRATULATIONS to Celine Camon, 2025 winner of the Julia Buckingham Award!

Celine will speak at #BSNBradford2025 on DHED, a brain specific 17βE2 prodrug, targets the hypothalamus but does not protect against metabolic dysfunction.

Register: bsnbradford2025.oa-e...
July 23, 2025 at 6:08 PM
🎉 Excited to share a new resource I’ve coordinated as the Early Career Researcher Rep for @bsneuroendo.bsky.social — a practical toolbox to support ECRs writing their first postdoctoral fellowship applications! Hope you find it helpful!
📄 Download it here:
www.neuroendo.org.uk/vendor/ckfin...
www.neuroendo.org.uk
July 29, 2025 at 10:12 PM
Reposted by Miguel Ruiz Cruz
🧠🍽️ Glp1r-Lepr coexpressing neurons in the dorsomedial hypothalamus modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist

🔗 www.science.org/doi/10.1126/...

#ingestivebehavior #weightloss #neuroskyence
Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist
Orthogonal murine models demonstrate the bioactivity and neuronal targets of a GLP-1/leptin coagonist in relation to food intake and body weight.
www.science.org
December 10, 2024 at 8:56 AM
Reposted by Miguel Ruiz Cruz
Check out our new ✨preprint ✨📝 describing extraordinary convergence of autism proteins at the cilium, a 🧵
www.biorxiv.org/content/10.1... (1/ )
Convergence of autism proteins at the cilium
Hundreds of high confidence autism genes have been identified, yet the relevant etiological mechanisms remain unclear. Gene ontology analyses have repeatedly identified enrichment of proteins with ann...
www.biorxiv.org
December 9, 2024 at 11:24 PM
Reposted by Miguel Ruiz Cruz
I am glad you didn’t show the Supplementary 😱
Abstract Vs. Results
December 8, 2024 at 10:24 PM
Reposted by Miguel Ruiz Cruz
Muchas gracias @fdescubre.bsky.social y @canalsurradio.bsky.social / @canalsurnoticias.bsky.social por permitirme compartir un poquito de ciencia con Andalucia y poder explicar nuestro último Science paper desarrollado en @dikiclab.bsky.social
www.canalsur.es/multimedia.h...
Fundación Descubre con Cristian Prieto
El investigador andaluz Cristian Prieto García publica en la prestigiosa revista 'Science' un artículo sobre una investigación en torno a la retinitis pigmentosa, una afección de la vista de carácter ...
www.canalsur.es
December 8, 2024 at 11:48 AM
Reposted by Miguel Ruiz Cruz
When you're having a nice dinner and make the mistake of taking a quick look at your phone only to see that your grant was rejected
December 9, 2024 at 3:22 PM
Reposted by Miguel Ruiz Cruz
Introducing my lab: we study how social stress impacts the brain and how these changes affect social behavior. We study California mice which are great for studying social stress in females and pubertal development (doesn't start until post-natal day 50).
December 7, 2024 at 5:21 PM
Reposted by Miguel Ruiz Cruz
Excited to share our new paper out now @natureportfolio.bsky.social, where we identified neural signatures of stress susceptibility and resilience in the amygdala-ventral hippocampal network to enable control of anhedonia!

Thread below:
December 4, 2024 at 5:46 PM
Reposted by Miguel Ruiz Cruz
Latest from our group in collaboration with Lotte Bjerre Knudsen and other Novo scientists. They developed a GLP-1/Leptin co-agonist that we put through its paces in a number of mouse models to prove that both parts of the molecule matter. More options on the table!
www.science.org/doi/10.1126/...
Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist
Orthogonal murine models demonstrate the bioactivity and neuronal targets of a GLP-1/leptin coagonist in relation to food intake and body weight.
www.science.org
December 4, 2024 at 8:27 PM
Reposted by Miguel Ruiz Cruz
🚨PhD opportunity in my lab🚨
I am thrilled to announce that I’m offering a fully funded PhD position in the prestigious BBSRC MIBTP (Midlands Integrative Biosciences Training Partnership) program!
💡Project Focus: The pregnant brain and the effects of high fat diet👇🏼
warwick.ac.uk/fac/cross_fa...
Dr Isadora Clivatti Furigo
Dr Isadora Clivatti Furigo
warwick.ac.uk
November 27, 2024 at 7:59 PM
Reposted by Miguel Ruiz Cruz
Happy to share with you our latest publication on the use of GLP-1 agonists in the treatment of metabolic disorders associated with polycystic ovary syndrome. We hope you enjoy it as much as we do! 🤩 @pubmetts.bsky.social

#PCOS #GLP1 #Hyperandrogenism #Obesity

www.nature.com/articles/s41...
Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy - Nature Communications
Metabolic complications are common in patients suffering PCOS, including obesity, insulin resistance and type-2 diabetes. Here the authors show the efficacy of GLP1-based multi-agonists, and superiori...
www.nature.com
December 4, 2024 at 5:07 PM
Reposted by Miguel Ruiz Cruz
Interested in lipid and metabolic sensing in the neuroendocrine control of weight and reproduction? 🧠 🍔🤰 Don’t miss out my latest review! @pubmetts.bsky.social

www.frontiersin.org/journals/end...
Frontiers | Emerging roles of lipid and metabolic sensing in the neuroendocrine control of body weight and reproduction
The hypothalamus lies at the intersection of brain and hormonal mechanisms governing essential bodily functions, including metabolic/body weight homeostasis ...
www.frontiersin.org
December 4, 2024 at 11:03 AM